The landscape of cell regulatory and communication networks in the human dental follicle by Jia-Ning Liu, Jia-Ning Liu, Jiong-Yi Tian, Lu Liu, Lu Liu, Yuan Cao, Yuan Cao, Xiao Lei, Xiao Lei, Xiao-Hui Zhang, Xiao-Hui Zhang, Zi-Qi Zhang, Zi-Qi Zhang, Jun-Xi He, Jun-Xi He, Chen-Xi Zheng, Chao Ma, Sheng-Feng Bai, Bing-Dong Sui, Fang Jin, Ji Chen, Ji Chen

“…IntroductionThe dental follicle localizes the surrounding enamel organ and dental papilla of the developing tooth germ during the embryonic stage. It can differentiate and develop to form the periodontal ligament, cementum, and alveolar bone tissues. …”
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Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling by Xi Xiao Huang, Ley Moy Ng, Po-Hsien Lee, Peiyong Guan, Mun Juinn Chow, Aisyah Binte Mohamed Bashir, Meina Lau, Kenric Yi Shu Tan, Zhimei Li, Jason Yongsheng Chan, Jing Han Hong, Sheng Rong Ng, Tun Kiat Ko, Hong Lee Heng, Hsiang Ling Teo, Daniela Rhodes, Patrick Tan, Puay Hoon Tan, Donald P. McDonnell, Bin Tean Teh

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A prospective multi-site study to evaluate the performance and usability of an oral fluid-based HIV self-test in Canada by Richard A. Galli, Darshanand Maraj, Kristin McBain, Jason M. Lo Hog Tian, Abbey McFarland, Wangari Tharao, Nontobeko P. Nkala, Arlene Chan, Mark da Silva, Rejean Thomas, Anne-Fanny Vassal, Martin Lepage, Laurie Ireland, Mike Payne, Jared Starr, Chris Fraser, Marion Selfridge, Mona Loutfy, Roberta Halpenny, Nirubini Jeyarajah, Vanessa Tran, Tony Mazzulli, Sean B. Rourke

Subjects: “…HIV testing…”
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Expanding first-line options for depression: Protocol of a pragmatic comparative effectiveness trial of yoga vs. behavioral activation (the COMPARE study) by Louisa G. Sylvia, Andrew M. Busch, Dustin J. Rabideau, Alexandra Gold, Suzanne C. Danhauer, Heather T. Schatten, Douglas Katz, Lauren M. Weinstock, Jennifer Dahne, Sabine P. Schmid, Zainab Soetan, Roberta Tovey, Kedie Pintro, Adrienne Kvaka, Antonietta Alvarez Hernandez, Ingrid Hsu, Alba Melendez, Melissa Adkins-Hempel, Angela Grubb, Odalys Lozado, Atefeh Alavi Fili, Giuliana Chau, Lisa A. Uebelacker

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Sustained immunogenicity of bivalent protein COVID-19 vaccine SCTV01C against antigen matched and mismatched variants by Guiqiang Wang, Kexin Zhao, Xiuli Zhao, Yimin Cui, Peng He, Tianzuo Zhang, Yanchao Wang, Rui Shi, Yanhua Li, Qian Wang, Yanping Ren, Zhisong Chen, Xuedan Zhao, Zekang Xie, Yufei Liang, Qingyun Tian, Jing Pan, Chao Zhang, Ying Han, Yuyang Dai, Siyang Ni, Yun Zhang, Xinjie Yang, Yongpan Fu, Dongfang Liu, Jing Li, Miaomiao Zhang, Zhongyu Hu, Liangzhi Xie

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Preclinical study and parallel phase II trial evaluating antisense STAT3 oligonucleotide and checkpoint blockade for advanced pancreatic, non-small cell lung cancer and mismatch re... by Heather Lin, Vivek Subbiah, Siqing Fu, Aung Naing, Courtney Nicholas, Shubham Pant, Chad Tang, Michael A Curran, David S Hong, Ying Yuan, Sarina A Piha-Paul, Jordi Rodon Ahnert, Timonthy A Yap, Apostolia M Tsimberidou, Daniel D Karp, Anupallavi Srinivasamani, Coline Couillault, Genevieve P Hartley, James Dai, Ecaterina E Ileana Dumbrava, Paola Guerrero, Sarah Dhebat, Theresa Proia

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A 10-year review of isoniazid-resistant TB management in Uzbekistan 2009-2020 by M.L. Rekart, P. Thit, M. Oluya, S. Moe, T. Hasan, N. Parpieva, K. Safaev, A. Khristusev, T. Zinaida, J. Singh, S. Allamuratova, I. Azamat, C.G. Restrepo, N. Sitali, J. Achar, J.L. Alvaraez, A. Sinha

“…Uzbekistan has a high burden of TB (62/100,000 population) and multidrug-resistant TB (12/100,000 population). …”
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Antioxidant, Physiochemical, and Sensory Properties of Functional Marshmallow Produced from Honey, Strawberry Concentrates, and Hibiscus Extract by Maher M. Al-Dabbas, Etaf G. Abu Samaan, Sehar Iqbal, Hani J. Hamad, Rawan Al-Jaloudi, Mohammad Shahein, Bha’a Aldin Al-Nawasrah, Abdalrahman Al-Zabt, Doa`a Al-Refaie, Nisreen Shehadeh, Mahmoud Abughoush

“…The results show that all formulations containing functional ingredients had significantly higher total phenolic and flavonoid contents, along with stronger antioxidant activities in a dose-dependent manner compared to the control. …”
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Durvalumab, Tremelimumab, and Platinum Chemotherapy in EGFR Mutation–Positive NSCLC: An Open-Label Phase 2 Trial (ILLUMINATE) by Chee Khoon Lee, PhD, Bin-Chi Liao, MD, Shalini Subramaniam, MMed (Clin Epi), Chao-Hua Chiu, MD, Antony J. Mersiades, MMed (Clin Epi), Chao-Chi Ho, MD, PhD, Chris Brown, MBiostats, Chun-Liang Lai, MD, PhD, Brett G.M. Hughes, M.B.B.S. (Hons), Tsung-Ying Yang, MD, PhD, Ken O’Byrne, MD, Yung-Hung Luo, MD, PhD, Sonia Yip, PhD, Ching-Liang Ho, MD, Victoria Bray, PhD, Wu-Chou Su, MD, PhD, Melissa Moore, PhD, Wei-Lien Feng, MS, Ya-Ying Bai, MS, Kate Ford, MHSc, Michelle M. Cummins, PhD, Martin R. Stockler, MSc (Clin Epi), Benjamin J. Solomon, PhD, Thomas John, PhD, James Chih-Hsin Yang, MD, PhD

“…The T790M− cohort had higher ORR and a longer duration of response. …”
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Clinical implementation of next-generation sequencing testing and genomically-matched therapy: a real-world data in a tertiary hospital by Jin Won Kim, Hee Young Na, Sejoon Lee, Ji-Won Kim, Koung Jin Suh, Se Hyun Kim, Yu Jung Kim, Keun-Wook Lee, Jong Seok Lee, Jaihwan Kim, Jin-Hyeok Hwang, Kihwan Hwang, Chae-Yong Kim, Yong Beom Kim, Soomin Ahn, Kyu Sang Lee, Hyojin Kim, Hye Seung Lee, So Yeon Park, Gheeyoung Choe, Jee Hyun Kim, Jin-Haeng Chung

“…Abstract Next-generation sequencing (NGS) cancer profiling has gained traction in routine clinical practice in South Korea. …”
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Extreme migratory connectivity and apparent mirroring of non-breeding grounds conditions in a severely declining breeding population of an Afro-Palearctic migratory bird by Máire Kirkland, Nathaniel N. D. Annorbah, Lee Barber, John Black, Jeremy Blackburn, Michael Colley, Gary Clewley, Colin Cross, Mike Drew, Oliver J. L. Fox, Vicky Gilson, Steffen Hahn, Chas Holt, Mark F. Hulme, John Jarjou, Dembo Jatta, Emmanuel Jatta, Kevin Leighton, Ernestina Mensah-Pebi, Chris Orsman, Naffie Sarr, Roger Walsh, Leo Zwarts, Robert J. Fuller, Philip W. Atkinson, Chris M. Hewson

“…Extremely low levels of population mixing were also detected, so any impacts on this population on the non-breeding grounds are unlikely to be shared with more distant breeding populations, corresponding to the observed patterns of European population change. According to a species distribution model using independent field data, this population’s non-breeding grounds had lower suitability than others and likely declined before the period we were able to assess. …”
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Application of molecular approach in combination with providing treatment and control measures for combating Babesia bovis and Babesia bigemina infections in small scale livestock... by Nutsuda Klinkaew, Pairpailin Jhaiaun, Giang Thi Nguyen, Ruttayaporn Ngasaman, Domechai Keawnoi, Niorn Rattanapob, Pipat Arunvipas, Meyanee Kanjanaphan, Nuttapon Manojai, Suwitcha Panchakhan, Julaluk Jaiboon, Piyavadee Numnual, Prattana Tong-in, Thongphanchang Khanthong, Paween Srirarai, Chutima Chantarakot, Pattarakitti Noenchat, Jaroonwit Napornram, Somtat Yangsuk, Tanakrit Cham-iam, Phuncharat Nilsuwan, Supicha Jindarut, Kanokrat Boonyok, Nipa Thammasonthijarern, Wissanuwat Chimnoi, Tawin Inpankaew, Burin Nimsuphan, Jumnongjit Phasuk, Ketsarin Kamyingkird

“…Molecular characterization of B. bovis SBP4 and B. bigemina RAP1a sequences showed that B. bigemina and B. bovis Thai isolates were closely related among geographical areas and shared genetic similarity among different hosts but were genetically distinct from B. bigemina and B. bovis from other countries. …”
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Real-world outcomes of Defocus Incorporated Multiple Segments lenses on retarding axial elongation in myopic children and adolescents by Rachel K. M. Chun, Rachel K. M. Chun, Rachel K. M. Chun, Kryshell Y. Q. Wong, Carly S. Y. Lam, Carly S. Y. Lam, Carly S. Y. Lam, Chi-ho To, Chi-ho To, Chi-ho To, Chi-ho To, Kenneth K. K. Liu, Yin-zhi Wong, Wing-chun Tang, Nicole Chan, Dora Kwok, Max Cheung, David Yung, Andrew K. C. Lam, Andrew K. C. Lam, Andrew K. C. Lam

“…The normalized annual changes in SER and AL in DIMS wearers were significantly smaller than those in SV wearers (DIMS; SER change vs. …”
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Radiofrequency ablation vs. cryoablation for pediatric atrioventricular nodal reentrant tachycardia in the era of three-dimensional electroanatomical mapping by Yao-Wei Chan, Chieh-Mao Chuang, Chieh-Mao Chuang, Pi-Chang Lee, I-Hsin Tai, I-Hsin Tai, I-Hsin Tai, Ying-Hsuan Peng, Ying-Hsuan Peng, Wen-Po Fan, Wen-Po Fan, Yu-Shin Lee, Ming-Chih Lin, Ming-Chih Lin, Sheng-Ling Jan, Sheng-Ling Jan, Yun-Ching Fu, Yun-Ching Fu, Shih-Ann Chen, Shih-Ann Chen

“…No major complications, such as permanent atrioventricular (AV) block, were observed. The minor complication rates, including transient AV block, did not differ significantly (14.5% vs. 11.5%, p > 0.99). …”
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Impact of primary care benefits on healthcare utilisation and estimated out-of-pocket expenses in urban, rural and remote settings in the Philippines by Antonio L Dans, Arianna Maever L Amit, Leonila F Dans, Gillian Sandigan, Regine Ynez H De Mesa, Mia P Rey, Josephine T Sanchez, Cara Lois T Galingana, Nannette Bernal-Sundiang, Maria Rhodora N Aquino, Johanna Faye E Lopez, Janelle Micaela S Panganiban, Romelei Camiling-Alfonso, Jose Rafael A Marfori, Ramon Pedro Paterno, Carol Stephanie Chua Tan-Lim, Noleen Marie Fabian, Chad Lester Lastrilla, Miguel Callo

“…In this study, two key outcomes were monitored: (1) monthly healthcare utilisation measured by the total number of outpatient consultations per site and (2) change in OOP expenses from baseline to endline within a 1 year study period.Results All sites had a positive trend in monthly outpatient consultations in healthcare utilisation over 1 year. …”
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Implementation of a goal-directed Care Bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial. by Menglu Ouyang, Anila Anjum, Francisca Gonzalez Mc Cawley, Mohammad Wasay, Lu Ma, Xin Hu, Xiaoying Chen, Alejandra Malavera, Xi Li, Paula Muñoz Venturelli, H Asita de Silva, Nguyen Huy Thang, Kolawole W Wahab, Jeyaraj D Pandian, Octavio M Pontes-Neto, Carlos Abanto, Venessa Cano-Nigenda, Antonio Arauz, Chao You, Stephen Jan, Lili Song, Craig S Anderson, Hueiming Liu, INTERACT3 Investigators

“…Trial registration: INTERACT3 is registered at Clinicaltrials.gov (NCT03209258) and the Chinese Clinical Trial Registry (ChiCTR-IOC-17011787).…”
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Cutting-edge Bioinformatics strategies for synthesizing Cyclotriazadisulfonamide (CADA) analogs in next-Generation HIV therapies by Jay Gabriel B. Larga, Wrynan T. Munabirul, Abu Tayab Moin, Md Maisum Sarwar Jyoti, Mst Sanjida Nasrin, Minhaz Abdullah Al Mueid, Abdul Ahad, Anwar Parvez, Mst Sabrina Yeasmin, Rupali M. Barhate, Rajesh B. Patil, Margel C. Bonifacio

“…Furthermore, CADA has shown a synergistic effect with clinically approved anti-HIV drugs, offering potential for enhanced therapeutic strategies (Vermeire & Schols, [65]). …”
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Observation of minimal and maximal speed limits for few and many-body states by Zitian Zhu, Lei Gao, Zehang Bao, Liang Xiang, Zixuan Song, Shibo Xu, Ke Wang, Jiachen Chen, Feitong Jin, Xuhao Zhu, Yu Gao, Yaozu Wu, Chuanyu Zhang, Ning Wang, Yiren Zou, Ziqi Tan, Aosai Zhang, Zhengyi Cui, Fanhao Shen, Jiarun Zhong, Tingting Li, Jinfeng Deng, Xu Zhang, Hang Dong, Pengfei Zhang, Zhen Wang, Chao Song, Chen Cheng, Qiujiang Guo, Hekang Li, H. Wang, Hai-Qing Lin, Rubem Mondaini

“…Inspired by the energy-time uncertainty principle, bounds have been demonstrated on the maximal speed at which a quantum state can change, resulting in immediate and practical tasks. …”
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Could cough hypersensitivity symptom profile differentiate phenotypes of chronic cough? by Mi-Yeong Kim, Ha-Kyeong Won, Ji-Yoon Oh, Ji-Hyang Lee, Eun-Jung Jo, Sung-Yoon Kang, Ji-Ho Lee, Seung-Eun Lee, Noeul Kang, Young-Chan Kim, Hwa Young Lee, Jin An, Youngsang Yoo, Ji-Su Shim, So-Young Park, Han-Ki Park, Min-Hye Kim, Sae-Hoon Kim, Sang-Heon Kim, Yoon-Seok Chang, Sang-Hoon Kim, Byung-Jae Lee, Surinder S. Birring, Woo-Jung Song

“…Background Recently, cough reflex hypersensitivity has been proposed as a common underlying feature of chronic cough in adults. …”
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APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology by Kristine M. Tran, Nellie E. Kwang, Claire A. Butler, Angela Gomez-Arboledas, Shimako Kawauchi, Cassandra Mar, Donna Chao, Rocio A. Barahona, Celia Da Cunha, Kate I. Tsourmas, Zechuan Shi, Shuling Wang, Sherilyn Collins, Amber Walker, Kai-Xuan Shi, Joshua A. Alcantara, Jonathan Neumann, Duc M. Duong, Nicholas T. Seyfried, Andrea J. Tenner, Frank M. LaFerla, Lindsay A. Hohsfield, Vivek Swarup, Grant R. MacGregor, Kim N. Green

“…Results In 5xFAD mice, ApoeCh enhances a Disease-Associated Microglia (DAM) phenotype in microglia surrounding plaques, and reduces plaque load, dystrophic neurites, and plasma neurofilament light chain. …”
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