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    Pharmacokinetic Properties and Therapeutic Effectiveness of Remimazolam in ICU Patients With Mechanical Ventilation: A Preliminary Study by Jing Hu, Yuhan Zhao, Litao Shao, Wenhui Zhang, Han Wang, Yun Liu, Mengxiang Su, Xiangrong Zuo

    Published 2025-06-01
    “…Sedation levels were mild to moderate at dosed of 0.1–0.3 mg/kg/h. Liver function significantly affected remimazolam metabolism, influencing the half‐life (R2 = 0.36, p = 0.00013) and clearance (R2 = 0.13, p = 0.04). …”
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  20. 3260

    A Prediction Model of Stable Warfarin Doses in Patients After Mechanical Heart Valve Replacement Based on a Machine Learning Algorithm by Bowen Guo, Cong Chen, Junhang Jia, Jubing Zheng, Yue Song, Taoshuai Liu, Kui Zhang, Yang Li, Ran Dong

    Published 2025-06-01
    “…Background: The narrow therapeutic range of warfarin, alongside the response of numerous influencing factors and significant inter-individual variability, presents major challenges for personalized medication. …”
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