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    Interorgan and Transcellular Communication in Metabolic Disease: Insights From Recent CMGH Studies by Tien S. Dong, Emeran Mayer

    Published 2025-01-01
    “…The gut microbiome and its metabolites, enteroendocrine signaling, bile acid regulation, and epithelial barrier functions now occupy center stage in dissecting the pathophysiology not only of gastroenterologic conditions, such as obesity, metabolic dysfunction-associated steatotic liver disease, and cirrhosis, but also of several disorders making up the chronic noncontagious disease epidemic.This paradigm shift is being driven by advances in molecular biology, systems biology, and computational modeling, which have enabled a holistic understanding of how communication between organs orchestrates metabolic homeostasis.1 Key to this understanding is the realization that local perturbations in 1 organ, such as gut microbial dysbiosis, can have systemic repercussions that affect distant organs, such as the liver or brain.2,3 This has redefined how researchers conceptualize disease progression and therapeutic interventions. …”
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    Feedback Regulation of sPLA2-COX/5-LOX-Ca2+ in Seminal Plasma and Its Impact on Sperm Quality Parameters by Liu Y, Dai L, Zhang F, Liu Y, Li X, Ma W

    Published 2025-06-01
    “…Yongjie Liu, Liang Dai, Fan Zhang, Yang Liu, Xu Li, Wenzhi Ma Reproductive Medical Center, Yinchuan Maternity and Child Health Care Hospital, Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, People’s Republic of ChinaCorrespondence: Wenzhi Ma, Reproductive Medical Center, Yinchuan Maternity and Child Health Care Hospital, Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, School of Basic Medical Sciences, Ningxia Medical University, No. 56 Wenhua West Street, Yinchuan, Ningxia, People’s Republic of China, Email mawenzhi126@126.com Yongjie Liu, Reproductive Medical Center, Yinchuan Maternity and Child Health Care Hospital, Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, School of Basic Medical Sciences, Ningxia Medical University, No. 56 Wenhua West Street, Yinchuan, Ningxia, People’s Republic of China, Email lyj1722006@126.comBackground: Male reproductive health is of growing concern. …”
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