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Identification and functional characterization of cardiac pacemaker cells in zebrafish.
Published 2012-01-01“…Through their long interconnecting cellular protrusions the identified Isl1-positive cells form a ring-shaped structure. …”
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A dual binding mode for RhoGTPases in plexin signalling.
Published 2011-08-01“…We present two crystal structures of the human Plexin-B1 cytoplasmic region in complex with a constitutively active RhoGTPase, Rac1. …”
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1865
From cooperation to collapse: systemic failure in liver disease through a sociological lens
Published 2025-07-01“…Sociological frameworks provide concepts such as incentive structures and collective action, which can be applied to cellular behavior. …”
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1866
Synthetic heparan sulfate oligosaccharides inhibit endothelial cell functions essential for angiogenesis.
Published 2010-07-01“…However, the significance of precisely defined HS structures in regulating cytokine-dependent angiogenic cellular functions and signalling through receptors regulating angiogenic responses remains unclear. …”
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1867
Claudin 4 in pancreatic β cells is involved in regulating the functional state of adult islets
Published 2020-01-01“…Furthermore, the genetic deletion of Cldn4 impaired significantly the FS without apparently affecting pancreas morphology, islet architectural structure and cellular distribution, and secretion of enteroendocrine hormones. …”
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1868
Placenta and Placental Derivatives in Regenerative Therapies: Experimental Studies, History, and Prospects
Published 2018-01-01“…In this review, the main features of the placenta and its derivatives such as structure, cellular composition, immunological and endocrine aspects, and the ability to invasion and deportation are discussed. …”
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1869
Development and deployment of a functional 3D-bioprinted blood vessel
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1870
Cisplatin and dexamethasone separate and combined effect on nephrotoxic processes in female rats
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1871
Biophysical properties of intrinsically disordered p130Cas substrate domain--implication in mechanosensing.
Published 2014-04-01“…Mechanical stretch-induced tyrosine phosphorylation in the proline-rich 306-residue substrate domain (CasSD) of p130Cas (or BCAR1) has eluded an experimentally validated structural understanding. Cellular p130Cas tyrosine phosphorylation is shown to function in areas without internal actomyosin contractility, sensing force at the leading edge of cell migration. …”
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1872
Immunopurification of pathological prion protein aggregates.
Published 2009-11-01“…The key event in these diseases is misfolding of the cellular prion protein (PrP(C)) into a pathogenic isoform that is rich in beta-sheet structure. …”
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1873
Evolution of the PE_PGRS Proteins of Mycobacteria: Are All Equal or Are Some More Equal than Others?
Published 2025-02-01“…Computational analysis and structural annotation using AlphaFold3 combined with other tools reveals an exceptionally powerful and unprecedented ability to undergo phase separation by the PGRS domain. …”
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1874
To the Question about Migration of Impurity Atoms in Graphene
Published 2013-10-01“…The anisotropy of the early migration stage can act as an instrument of the matrix state diagnosis and also the formation of the specified impurity geometric structures which are jointed with graphene. The diffusive spread rate, which is compared with the rate of the cellular migration spread, is found. …”
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Stepwise order in protein complex assembly: approaches and emerging themes
Published 2025-01-01“…Protein-based nanomachines drive every cellular process. An explosion of high-resolution structures of multiprotein complexes has improved our understanding of what these machines look like and how they work, but we still know relatively little about how they assemble in living cells. …”
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Effect of <i>Satureja montana</i> Essential Oil on Model Lipid Membranes
Published 2024-12-01“…This antimicrobial effect is often attributed to its ability to penetrate cellular structures and disrupt them. Although these properties are recognized as playing a key role in the mechanism of action of this substance, many unresolved issues still exist, and fundamental studies focused on such aspects are scarce. …”
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Regulation of Blood–Brain Barrier Permeability via JNK Signaling Pathway: Mechanisms and Potential Therapeutic Strategies for Ischemic Stroke, Alzheimer’s Disease and Brain Tumors...
Published 2025-05-01“…In recent years, it has become clear that the c-Jun N-terminal kinase (JNK) signaling pathway is involved in disruption of the structural integrity of the BBB. Activation of the JNK signaling pathway has a negative effect on the functioning of the cellular elements of the neurovascular unit that form the BBB. …”
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HUMAN AMNIOTIC EPITHELIAL CELLS FOR RETINAL REGENERATION: INVESTIGATING THEIR DIFFERENTIATIVE POTENTIAL IN VITRO
Published 2025-08-01“…Its emerging application in retinal repair -particularly for macular holes, retinal tears, and age-related macular degeneration (AMD)- typically focuses on structural or paracrine support, often overlooking its cellular components. …”
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Conduction velocity, G-ratio, and extracellular water as microstructural characteristics of autism spectrum disorder.
Published 2024-01-01“…We conclude that ASD may be characterized by otherwise intact structural connectivity but that functional connectivity may be attenuated by network properties affecting neural transmission speed. …”
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Organization of the Interstitial Component of Gallbladder Muscle Tissue in Guinea Pigs
Published 2025-03-01“…It can be stated that there is no clear understanding of the structural and functional organization of ICCs and TCs or their probable role in maintaining the structural homeostasis of organs, which necessitates further research.…”
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