Discoidin domain receptors; an ancient family of collagen receptors has major roles in bone development, regeneration and metabolism by Renny T. Franceschi, Shawn A. Hallett, Chunxi Ge

“…As the major ECM component in mineralized tissues, collagen has instructive as well as structural roles during bone development and is required for bone cell differentiation. …”
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Bronchial Asthma in Youth: A Brief Concept Review by Roberto W. Dal Negro

“…It is characterized by a huge personal, familial, and societal impact. Biological and cellular studies in recent decades define asthma as a chronic inflammatory disease of the airways. …”
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Dissection of surface area-dependent lipolysis at a single organelle level by Chengxin Ma, Yan Liang, Xinmeng Che, Yuqi Li, Jin Wu, Li Xu, Hongyuan Yang, Tong-Jin Zhao, Feng-Jung Chen, Peng Li

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Assay development and screening of inhibitors targeting the SARS-CoV-2 2′-O-methyltransferase NSP16 by Mengtong Cao, Carl W. Trieshmann, Subodh Kumar Samrat, Hongmin Li, Yifei Wu, Steven P. Maher, Angela A. Bae, Zhong-Ru Xie, Robert J. Hogan, Y. George Zheng

“…We identified potential hits that inhibit the NSP16 activity with cellular efficacy. Together with structural analysis and chemotype categorization, this study lays the groundwork for novel antiviral therapeutics development against SARS-CoV-2 and related coronaviruses.…”
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TET dioxygenases localize at splicing speckles and promote RNA splicing by Florian D. Hastert, Jasmin Weber, Christina Bauer, Andreas Zhadan, Deepanshu N. D. Singh, Thomas C. Dix, Roland Arnold, Sergey Bessonov, Matthias Soller, Heinrich Leonhardt, M. Cristina Cardoso, Maria Arroyo

“…The dynamic regulation of RNA metabolism plays a crucial part in cellular function, with emerging evidence suggesting an important role for RNA modifications in this process. …”
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Effect of solution-aging treatment on the microstructure and hydrogen embrittlement susceptibility in laser-powder bed fusion maraging steel by Nan Zhou, Youpeng Xie, Yuyan Xiao, Xiaoyu Wang, Zhixian Peng, Zhaoyang Cheng, Jing Liu, Feng Huang, Shiqi Zhang

“…The slow strain rate tests further reveal solution-aging reduces HE resistance, which primarily caused by the vanishment of cellular structures, grain coarsening, the additional reversible H-traps provided by precipitates, and the enhancement in strength. …”
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Genetic surveillance reveals low but sustained malaria transmission with clonal replacement in Sao Tome and Principe by Ying‑An Chen, Peng-Yin Ng, Daniel Garcia-Ruiz, Aaron Elliot, Brian Palmer, Ronalg Mendes Costa d’ Assunção Carvalho, Lien-Fen Tseng, Cheng-Sheng Lee, Kun-Hsien Tsai, Bryan Greenhouse, Hsiao-Han Chang

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Estimating Cell Count and Distribution in Labeled Histological Samples Using Incremental Cell Search by Oscar E. Meruvia-Pastor, Jung Soh, Eric J. Schmidt, Julia C. Boughner, Mei Xiao, Heather A. Jamniczky, Benedikt Hallgrímsson, Christoph W. Sensen

“…Cell proliferation is critical to the outgrowth of biological structures including the face and limbs. This cellular process has traditionally been studied via sequential histological sampling of these tissues. …”
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Exploring focal adhesion data: dynamic parameter extraction from FRAP and FLAP experiments using chemical master equation by Luciana Renata de Oliveira, Matheus Gimenez Fernandes, José Salvatore Leister Patane, Jean-Marc Schwartz, José Eduardo Krieger, Christoph Ballestrem, Ayumi Aurea Miyakawa

“…The dynamic behavior of proteins within cellular structures can be studied using fluorescence recovery after photobleaching (FRAP) and fluorescence loss after photobleaching (FLAP) experiments. …”
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Investigating the relationship between serum zinc levels and red blood cell indices in anemic patients referred to the laboratories in Gorgan, Iran by Zahra Eslami, Shayan Marhamaty, Seyyed Mehdi Jafari, Mohadese Khorasani, Mehdi Sheikh Arabi, Hamidreza Joshaghani

“…Specifically, zinc (Zn) assumes catalytic, structural, and regulatory roles in numerous biological processes. …”
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In situ magnetic-field-assisted bioprinting process using magnetorheological bioink to obtain engineered muscle constructs by Hanjun Hwangbo, SooJung Chae, Dongryeol Ryu, GeunHyung Kim

“…Herein, we propose the concept of a magnetorheological bioink to manipulate the cellular arrangement within a low-viscosity hydrogel. …”
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Effects of copper and copper oxide nanoparticles on cyanobacterium Nostoc linckia: an experimental study by Liliana Cepoi, Ludmila Rudi, Tatiana Chiriac, Ana Valuta, Svetlana Codreanu, Tatiana Mitina, Liviu Codreanu

“…Both nanoparticle types, however, caused notable bioaccumulation of copper and structural modification in Nostoc linckia cells expressed in trichome fragmentation, chromaticity changes, and variations in heterocyst numbers and size in treated samples.ConclusionCuNPs and CuONPs exhibit differential effects on Nostoc linckia, influencing biochemical composition, pigment profiles, and cellular structure. …”
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Innovative hydrogels in cutaneous wound healing: current status and future perspectives by Prasad Sawadkar, Prasad Sawadkar, Ferdinand Lali, Ferdinand Lali, Elena Garcia-Gareta, Elena Garcia-Gareta, Elena Garcia-Gareta, Elena Garcia-Gareta, Beatriz Gil Garrido, Abdullah Chaudhry, Priya Matharu, Christos Kyriakidis, Karin Greco, Karin Greco

“…Hydrogels, both of natural and synthetic origin, have emerged as versatile biomaterials for wound management due to their structural adaptability, biocompatibility, and tunable physicochemical properties. …”
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Tuning antibody stability and function by rational designs of framework mutations by Joseph C. F. Ng, Alicia Chenoweth, Maria Laura De Sciscio, Melanie Grandits, Anthony Cheung, Tooki Chu, Alexandra McCraw, Jitesh Chauhan, Yi Liu, Dongjun Guo, Semil Patel, Alice Kosmider, Daniela Iancu, Sophia N. Karagiannis, Franca Fraternali

“…We first showed that recent antibody-specific language models lacked insights in FW mutagenesis, in comparison to approaches that use antibody structure information. Using the widely used breast cancer therapeutic trastuzumab as a use case, we designed stabilizing mutants which were distal to the CDR and preserved the antibody’s functionality to engage its cognate antigen (HER2) and induce antibody-dependent cellular cytotoxicity. …”
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LncRNAs Regulate Vasculogenic Mimicry in Human Cancers by Eloísa Ibarra-Sierra, Mercedes Bermúdez, Carlos Esteban Villegas-Mercado, Macrina B. Silva-Cázares, César López-Camarillo

“…During VM, tumor cells align and organize themselves into three-dimensional (3D) channel-like structures to transport nutrients and oxygen to the internal layers of tumors. …”
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Extracellular vesicles: the “Trojan Horse” within breast cancer host microenvironments by Yue Kang, Ling’ao Meng, Shi Bai, Shenglong Li

“…Extracellular vesicles (EVs) are membrane-bound structures characterized by phospholipid bilayers, capable of secretion by a multitude of cell types. …”
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Advancing dimensionality reduction for enhanced visualization and clustering in single-cell transcriptomics by P. Sanju

“…Traditional techniques like principal component analysis, though fundamental, often struggle to capture the full complexity of diverse cellular populations. Nonlinear dimensionality reduction methods have emerged as powerful alternatives, offering a more detailed and accurate representation of cellular relationships. …”
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Molecular correlates of childhood adversity – a multi-omics perspective on stress regulation by Johannes C. S. Zang, Caroline May, Katrin Marcus, Robert Kumsta

“…In search of mediators of this relationship, alterations of bio-behavioral and cellular regulatory systems came into focus, including those dealing with basic gene regulatory processes. …”
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Heavy metal(loid) bioaccumulation in fish and its implications for human health by Dhary Alewy Almashhadany, Rzgar Farooq Rashid, Khalil Ibrahim Altaif, Sarhang Hayyas Mohammed, Hero Ismael Mohammed, Salah Mahdi Al-Bader

“…Their long-term accumulation can result in chronic toxicity even at low levels of exposure. HMs exert cellular cytotoxicity by disrupting essential cellular processes and structures. …”
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Multifaceted roles of Galectins: from carbohydrate binding to targeted cancer therapy by Nan Zhang, Qiao Liu, Daihan Wang, Xiaoyun Wang, Zhaoping Pan, Bo Han, Gu He

“…Abstract Galectins play pivotal roles in cellular recognition and signaling processes by interacting with glycoconjugates. …”
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