BubR1 Controls Heart Development by Promoting Expression of Cardiogenesis Regulators by Renju Pun, Aradhana Thapa, Sylar R. Takafuji, Rexton M. Suzuki, Gabrielle F. Kay, Toni D. Howard, Michael H. Kim, Brian J. North

“…Methods To study morphological, structural, and cellular consequences of BubR1 deletion in the heart, we crossed mice carrying conditional alleles of Bub1b with Nkx2.5‐cre mice. …”
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All-natural ceramic composite bone scaffolds of whitlockite/wollastonite fibers: DLP additive manufacturing, microstructure, and performance by Wang Guo, Lei Zhao, Ping Li, Enyu Wang, Yuanheng Pang, Yanting Wei, Bowen Li, Yanjian Huang, Bin Liu, Shan Wang, Hui You, Yu Long

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Modulation of Nuclear Receptor Action and Regulation of Medicines Biotransformation by S. N. Larina, N. V. Chebyshev, E. V. Shikh

“…The structural basis of the receptor provides interaction with a variety of ligands which are agonists or antagonists. …”
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Endoplasmic reticulum-mitochondria crosstalk: new mechanisms in the development of atherosclerosis by Mingxiao Li, Yili Xiao, Ling Dai, Simin Chen, Wanjuan Pei, Chao Tan, Chao Tan

“…Recent studies have highlighted the significance of ER-mitochondria crosstalk in the progression of AS, as indicated by mitochondrial and ER structural and functional integrity, redox homeostasis, and calcium homeostasis. …”
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Coupling of ribosome biogenesis and translation initiation in human mitochondria by Marleen Heinrichs, Anna Franziska Finke, Shintaro Aibara, Angelique Krempler, Angela Boshnakovska, Peter Rehling, Hauke S. Hillen, Ricarda Richter-Dennerlein

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Mitochondrial disorders in children: toward development of small‐molecule treatment strategies by Werner JH Koopman, Julien Beyrath, Cheuk‐Wing Fung, Saskia Koene, Richard J Rodenburg, Peter HGM Willems, Jan AM Smeitink

“…We focus on pathologies due to mutations in nuclear DNA‐encoded structural and assembly factors of the mitochondrial oxidative phosphorylation (OXPHOS) system, with a particular emphasis on isolated mitochondrial complex I deficiency. …”
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Shock Energy Conversion from Translation to Rotation by Hongyuan Zhou, Xiaojuan Wang, Xuejian Zhang

“…Different from conventional methods with cellular solid/structure dissipating input translational kinetic energy to plastic strain energy with large compressive deformation, the proposed approach converts part of incident translational kinetic energy to rotational kinetic energy, which is not detrimental to the protected structure. …”
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Neuromorphic deviations associated with transcriptomic expression and specific cell type in Alzheimer’s disease by Jinzhong Peng, Qin Tang, Yilu Li, Lin Liu, Bharat Bhusan Biswal, Pan Wang

“…The study map the disease-specific structural alterations in AD down to the cellular level, offering a novel perspective on the linking surface-level changes to molecular mechanisms.…”
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MPicker: visualizing and picking membrane proteins for cryo-electron tomography by Xiaofeng Yan, Shudong Li, Weilin Huang, Hao Wang, Tianfang Zhao, Mingtao Huang, Niyun Zhou, Yuan Shen, Xueming Li

“…Abstract Advancements in cryo-electron tomography (cryoET) allow the structure of macromolecules to be determined in situ, which is crucial for studying membrane protein structures and their interactions in the cellular environment. …”
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Elucidating ATP’s role as solubilizer of biomolecular aggregate by Susmita Sarkar, Saurabh Gupta, Chiranjit Mahato, Dibyendu Das, Jagannath Mondal

“…Computer simulation links ATP’s solubilizing role to its ability to modulate protein’s structural plasticity by unwinding protein conformation. …”
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Nuclear lipid signalling Symposium by FA Manzoli

“… Since 46 years ago, when Hokin and Hokin presented the first evidence of an enhanced incorporation of [32P] orthophosphate only into phosphatidylinositol (PI) after stimulation of tissue slices with acetylcholine, the biological role of phospholipids has been confined to the structural organisation of cellular membranes. Stemming from this pionieristic observation an increasing body of evidence pointed out the essential role of inositol phospholipids in cellular signalling and more recently become clear that also other phospholipids contribute to the complex machinery of intracellular signalling, namely phosphatidylcholine (PC) and sphingomyelin (SM). …”
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Cytoarchitecture of the Hippocampal Subfields CA3, CA4, and the Dentate Gyrus in Human Cerebrum: A Detailed Histological Analysis by Suvarna Anil Rampelliwar, Anjali Sabnis, Manisha Tambekar

“…CA3, CA4, and dentate gyrus, its analysis of the thickness of layers (μ) and cellular dimensions (μ), and analysis of radial glial cells. …”
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Biological Functionalities of Transglutaminase 2 and the Possibility of Its Compensation by Other Members of the Transglutaminase Family by Benedict Onyekachi Odii, Peter Coussons

“…It is a unique member of the transglutaminase family owing to its specialized biochemical, structural and functional elements, ubiquitous tissue distribution and subcellular localization, and substrate specificity. …”
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Anterior tenting vs. whole wrapping technique for acellular dermal matrix in breast reconstruction under post-mastectomy radiotherapy in rats by Ji-Young Kim, Ung Sik Jin

“…In our rat model, the whole wrapping technique led to a greater increase in intraprosthetic pressure due to radiation-related structural changes in ADM, compared to the anterior-tenting technique.…”
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Harvesting decellularized liver extracellular matrix from rodents for 3D scaffold fabrication by Meghana Kasturi, Kirthanashri S. Vasanthan

“…Decellularization is a process to harvest the decellularized extra cellular matrix (dECM) that helps develop 3D scaffolds which mimic the native tissue composition. …”
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MESENTERIC LYMPH NODES IN SIMULATED RECTAL CANCER UNDER CONDITIONS OF CHEMOTHERAPY by N. B. Isakova, E. V. Starkova

“…Under conditions of tumor growth, significant changes in structural organization, activation of proliferative process and blast transformation in areas responsible for cellular and humoral immune response were found in mesenteric lymph nodes. …”
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Pathomorphological changes in the periodontal complex tissues in the period of experimental bacterial-immune periodontitis chronization by A. Ye. Demkovych, Yu. I. Bondarenko, T. K. Нolovata

“…Morphological analysis was used for estimation of the structural changes degree in the maxillofacial tissues. …”
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DeepCycle reconstructs a cyclic cell cycle trajectory from unsegmented cell images using convolutional neural networks by Luca Rappez, Alexander Rakhlin, Angelos Rigopoulos, Sergey Nikolenko, Theodore Alexandrov

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Dynamic fibrillar assembly of αB-crystallin induced by perturbation of the conserved NT-IXI motif resolved by cryo-EM by Russell McFarland, Rozhan Noroozi, Adam P. Miller, Steve L. Reichow

“…Abstract αB-crystallin is an archetypical member of the small heat shock proteins (sHSPs) vital for cellular proteostasis and mitigating protein misfolding diseases. …”
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The processes of lipid peroxidation in children with the attention deficit hyperactivity disorder and different interhemispheric relations of brain by E. V. Osipova, L. A. Grebyonkina, V. I. Mikhnovich, M. I. Dolgikh

“…The processes of lipid peroxidation have damaging effect on a cell by altering the structure of cell membranes. The aim of the study was to investigate peculiarities of the carbohydrate and lipid metabolism, peroxidation that determine the normal functioning of metabolic and cellular homeostasis in children with attention deficit hyperactivity disorder, and different hemispheric relations. 54 children of 7-11 years, living in Irkutsk, were examined. …”
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