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NATURAL KILLER CELL EFFECTS UPON ANGIOGENESIS UNDER CONDITIONS OF CONTACT-DEPENDENT AND DISTANT CO-CULTURING WITH ENDOTHELIAL AND TROPHOBLAST CELLS
Published 2019-07-01“…Introduction of NK cells to the co-culture of endothelial and trophoblast cells under conditions of both contact and distance-dependent culturing did not change the length of tube-like structures formed by endothelial cells. During contact-dependent culturing of NK cells with co-culture of endothelial and trophoblast cells in presence of IL-1β, the length of tubule-like structures remained unchanged, compared with the length of tube-like structures formed under the same culturing conditions, but without the cytokine added. …”
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1643
Comparative Analysis of ARIMA, Prophet, and Glmnet for Long Term Evolution (LTE) Base Station Traffic Forecasting
Published 2024-12-01“…Its ability to handle complex data structures, manage multicollinearity, and deliver robust and accurate predictions makes it the preferred choice for forecasting cellular network traffic in the telecommunications domain. …”
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1644
Using Small Molecules to Reprogram RPE Cells in Regenerative Medicine for Degenerative Eye Disease
Published 2024-11-01“…Depending on the goal, which can be the preservation or the replacement of lost RPE cells and cellular structures, various small molecules are used to influence certain biological processes at different levels of cellular regulation. …”
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1645
Progressive multifocal leukoencephalopathy in HIV-infected patients: clinical features and diagnosis (literature review)
Published 2019-10-01“…Progressive multifocal leukoencephalopathy (PML) is one of the most severe opportunistic diseases of the central nervous system, which leads to multiple demyelination of brain structures, neurological symptoms and frequent death or disability of the patient. …”
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1646
The TIP60-CD44 Axis Modulates Colorectal Cancer Stemness
Published 2025-05-01“…The depletion of <i>TIP60</i> resulted in a marked decrease in cellular proliferation, highlighting TIP60’s involvement in the progression of CRC. …”
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Prion Protein Misfolding, Strains, and Neurotoxicity: An Update from Studies on Mammalian Prions
Published 2013-01-01“…The central event in TSE pathogenesis is the conformational conversion of the cellular prion protein, PrPC, into the aggregate, β-sheet rich, amyloidogenic form, PrPSc. …”
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1648
Research advances of single-cell RNA sequencing in kidney
Published 2021-01-01“…Composed of multiple cell types,kidney is an organ with highly complex structures and functions.Thus it is quite important to clarify the gene transcription map and changes of various types and subtypes of cells under physiological and pathological conditions to elucidate the structure,function and pathogenesis of the diseases.The development of single-cell RNA sequencing has triggered a shift in transcriptomic researches from analyzing the average level of gene transcription in various tissues to transcribing single-cell genes in specific organs(or tissues)at the cellular level.Based upon the elaboration of scRNA-seq technology and the newly discovered subtypes and functions of kidney cells,this review focused upon research advances of scRNA-seq of immune cells in kidney tissues of common kidney diseases.…”
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Ways to Implement Non-Antibacterial Effects of Antibiotics Widely Used in Clinical Practice
Published 2020-05-01“…A dose-dependent effect of structural modifications of cells, determined by the time of interaction with antibiotics and their chemical structure, was revealed. …”
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Ticking time: How does aging affect tympanal organ integrity in female crickets? A descriptive study
Published 2025-08-01“…We hypothesized that structural degradation of the posterior tympanal membrane (PTM) increases with age, potentially impairing auditory perception. …”
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Genome Instability and Senescence Are Markers of Cornelia de Lange Syndrome Cells
Published 2024-12-01“…Pathogenic variants in genes encoding the structural subunits and regulatory proteins of the cohesin complex (<i>NIPBL</i>, <i>SMC1A</i>, <i>SMC3</i>, <i>HDAC8</i>, and <i>RAD21</i>) are the primary contributors to the pathogenesis of CdLS. …”
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Analysis of biofilm assembly by large area automated AFM
Published 2025-05-01“…While atomic force microscopy (AFM) offers critically important high-resolution insights on structural and functional properties at the cellular and even sub-cellular level, its limited scan range and labor-intensive nature restricts the ability to link these smaller scale features to the functional macroscale organization of the films. …”
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Cerebellar microglia: On the edge between neuroinflammation and neuroregulation
Published 2026-01-01“…These immune cells communicate with intrinsic and systemic factors and contribute to the structural and functional compartmentalization of the cerebellum. …”
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Mitigating Cell Cycle Effects in Multi‐Omics Data: Solutions and Analytical Frameworks
Published 2025-08-01“…Abstract Cell cycle structures vary significantly across cell types, which exhibit distinct phase compositions. …”
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Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity
Published 2025-03-01“…By exploiting a modular structure-based framework and molecular dynamics simulations, we investigated the effect of five TRAP1 mutations on its structure and stability. …”
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Guanine quadruplexes mediate mitochondrial RNA polymerase pausing
Published 2025-05-01“…Abstract Background The information content within nucleic acids extends beyond the primary sequence to include secondary structures with functional roles in transcription regulation. …”
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Spatial dimension of macrophage heterogeneity in liver diseases
Published 2023-08-01“…The structural and cellular organisation of the liver has unique features that define it as both a metabolic and an immunological organ. …”
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Workflow for Fluorescence-Targeted Lamella Milling From Vitrified Cells With a Coincident Fluorescence, Electron, and Ion Beam Microscope
Published 2025-07-01“…Cryo-electron tomography (cryo-ET) is the main technique to image the structure of biological macromolecules inside their cellular environment. …”
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Engineering of ATP synthase for enhancement of proton-to-ATP ratio
Published 2025-07-01“…This study not only provides valuable insights into the H+-transport mechanism of FoF1 but also opens up possibilities for engineering the foundation of cellular bioenergetics.…”
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