Suggested Topics within your search.
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1621
Morphological and immunohistochemical peculiarities of oncomarkers in placental barrier
Published 2012-04-01“…In 1st investigation group in I pregnancy trimester in placental barrier structures there were pronounced expression of proliferative marker (Ki-67), protein p53 and decrease of these markers in III trimester that is proved by indexes of proliferation and it is caused by regulating infl uence of these factors on the processes of growth, development, differentiation and cell death in placental barrier structures in pregnancy course. …”
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1622
BiP Proteins from Symbiodiniaceae: A “Shocking” Story
Published 2024-10-01“…More than four decades ago, the discovery of a companion protein of immunoglobulins in myeloma cells and soon after, of their ability to associate with heavy chains, made the term immunoglobulin binding protein (BiP) emerge, prompting a tremendous amount of effort to understand their versatile cellular functions. BiPs belong to the heat shock protein (Hsp) 70 family and are crucial for protein folding and cellular stress responses. …”
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1623
In vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoforms.
Published 2009-06-01“…Prion diseases are incurable neurodegenerative disorders in which the normal cellular prion protein (PrP(C)) converts into a misfolded isoform (PrP(Sc)) with unique biochemical and structural properties that correlate with disease. …”
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1624
The Memory Lag Regulates the Threshold Effect Within the Repressor Gene Module
Published 2025-03-01“…Here, we try to investigate a prototypical regulatory network coupled with random fluctuations (noise) and nonlinear structures to focus on the impact of protein abundance fluctuations within bacteriophages on cellular phenotypic transitions and energy dissipation throughout the process. …”
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1625
Modifying treatment of degenerative retinal diseases. Part 1. Adaptive and non-adaptive retinal plasticity
Published 2023-07-01“…In many cases, the response to these damages is identical at both the cellular and molecular levels, involves similar sets of cellular signals, and is associated with a change in the structure of the retina and remodeling of the neural connections. …”
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1626
Phototherapy in treatment of rare dermatoses
Published 2024-12-01“…The similarities and differences of the effects on cellular structures of different spectral ranges are described. …”
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1627
APOBEC affects tumor evolution and age at onset of lung cancer in smokers
Published 2025-05-01Get full text
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1628
A Review of Natural and Synthetic Chalcones as Anticancer Agents Targeting Topoisomerase Enzymes
Published 2025-06-01“…These compounds are characterized by an open-chain structure and an α,β-unsaturated carbonyl moiety that enables interaction with cellular targets. …”
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1629
Heat application in live cell imaging
Published 2024-12-01“…Thermal heating of biological samples allows to reversibly manipulate cellular processes with high temporal and spatial resolution. …”
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1630
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1631
Fatty acid composition of total lipids and phospholipids of muscular tissue and brain of rats under the impact of vibration
Published 2016-06-01“…Fatty acids are important structural components of biological membranes, energy substrate of cells involved in fixing phospholipid bilayer proteins, and acting as regulators and modulators of enzymatic activity. …”
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1632
The Notch pathway in Metazoa: a comparative analysis across cnidarians and beyond
Published 2025-06-01“…Abstract The Notch signalling pathway is a conserved regulator of cellular processes, including differentiation, proliferation, and apoptosis, across Metazoa. …”
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1634
In Silico Design and Characterization of a Multiepitope Vaccine Candidate Against Brucella canis Using a Reverse Vaccinology Approach
Published 2025-01-01“…Validation of its secondary and tertiary structures, along with molecular docking analysis, revealed a high binding affinity to the TLR4 receptor. …”
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1635
Combined Mulberry Leaf Polysaccharide-Caged Liposomes for Effective Oral Drug Delivery in Rat Model
Published 2025-04-01“…MLP-CL also enabled more effective co-delivery of MLP and liposomes to MDCK cells, indicating improved structural integrity and cellular uptake. Transcellular transport assay confirmed that MLP-CL was transported across cells more efficiently. …”
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1636
Progress in the Study of Dry Shrinkage Deformation and Drying Stress of Raw Bamboo
Published 2025-02-01“…It reviews literature on bamboo drying and cellular structural changes, evaluating the evolution of stress and strain testing methods, from traditional sectioning techniques to advanced methods such as digital imaging and acoustic emission. …”
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1637
Advances in the Development of Mitochondrial Pyruvate Carrier Inhibitors for Therapeutic Applications
Published 2025-02-01“…This review provides an overview of the MPC complex, examining its structural components, regulatory mechanisms, and biological functions. …”
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1638
The Role of the Pathoanatomical Diagnosis «Chronic Gastritis» in the System of Personified Cancer Prevention
Published 2018-09-01“…The aim of the review is to systematize the principles of interpretation of morphological and molecular-cellular signs underlying the biopsy diagnosis of chronic gastritis from the standpoint of personified prevention of gastric cancer.Background. …”
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1639
A Transcriptomic Dataset of Embryonic Murine Telencephalon of Fmr1-Deficient Mice
Published 2025-06-01Get full text
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1640
Tumor Niche Influences the Activity and Delivery of Anticancer Drugs: Pharmacology Meets Chemistry
Published 2025-07-01“…These structures include both cellular and matrix components and have been shown to protect and promote cancer formation and progression. …”
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