Small molecule BLVRB redox inhibitor promotes megakaryocytopoiesis and stress thrombopoiesis in vivo by Natasha M. Nesbitt, Gian Luca Araldi, Lisa Pennacchia, Natalia Marchenko, Zahra Assar, Kendall M. Muzzarelli, Rahul Raghavan Thekke Veedu, Brian Medel-Lacruz, Eunjeong Lee, Elan Z. Eisenmesser, Dale F. Kreitler, Wadie F. Bahou

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Unveiling the evolutionary pathways of Ochoterenella: a new species discovery and its phylogenetic implications by Gabriel Lima Rebêlo, Jorge Kevin Silva Neves, Fred Gabriel Haick, Ronald Ferreira Jesus, Karina Varella, Luiz Felipe Ferreira Trindade, Leticia de Aguiar da Costa, Fabrícia de Jesus Paiva da Fonseca Sizo, Arnaldo Maldonado Júnior, Carlos Eduardo Costa-Campos, Francisco Tiago Vasconcelos Melo

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De novo design of protein minibinder agonists of TLR3 by Chloe S. Adams, Hyojin Kim, Abigail E. Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Adri Tran-Pearson, Ho Min Kim, Neil P. King

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Morphological multiparameter filtration and persistent homology in mitochondrial image analysis. by Yu-Min Chung, Chuan-Shen Hu, Emily Sun, Henry C Tseng

“…We show that such filtrations contain both topological and geometric information about complex cellular organelle structures, which allows a software program to extract meaningful features. …”
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A high-throughput colorimetric screening assay for terpene synthase activity based on substrate consumption. by Maiko Furubayashi, Mayu Ikezumi, Jun Kajiwara, Miki Iwasaki, Akira Fujii, Ling Li, Kyoichi Saito, Daisuke Umeno

“…Terpene synthases catalyze the formation of a variety of terpene chemical structures. Systematic mutagenesis studies have been effective in providing insights into the characteristic and complex mechanisms of C-C bond formations and in exploring the enzymatic potential for inventing new chemical structures. …”
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Effect of elastic modulus of tumour and non-tumour cells on vibration-induced behaviours by BonHeon Ku, Jing Liu, Sungsoo Na, Hiroki Yokota, Chinsuk Hong, HeeChang Lim

“…This study investigates the vibration-induced mechanical behaviour in cellular structures with varying elastic moduli (E = 0.1 , 1 , and 10 kPa) and aspect ratios ( $$AR = 2$$ and 4), focusing on vertical and horizontal forced vibrations. …”
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Alteration of Tight and Adherens Junctions on 50-Hz Magnetic Field Exposure in Madin Darby Canine Kidney (MDCK) Cells by Zoltán Somosy, Zsolt Forgács, Gabriella Bognár, Katalin Horváth, Gyözo Horváth

“…They are responsible for cell-to-cell interactions and also have great importance in cellular signaling processes including Wnt protein-mediated signals. …”
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Magnesium-reinforced PMMA composite scaffolds: Synthesis, characterization, and 3D printing via stereolithography by Afridi Ambreen, Kalva Sumama Nuthana, Al Rashid Ans, Al-Maslamani Noor A., Koç Muammer

“…The primary focus of these research efforts has been on determining the optimal materials and methods for creating these scaffolds, ensuring that they are biocompatible, capable of withstanding structural strains, and can support cellular proliferation, tissue growth, and vascularization. …”
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Nuclear PKM2: a signal receiver, a gene programmer, and a metabolic modulator by Tsan-Jan Chen, Chun-Hsien Wu, Mien-Chie Hung, Wen-Ching Wang, Hsing-Jien Kung

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The peptidoglycan-associated protein NapA plays an important role in the envelope integrity and in the pathogenesis of the lyme disease spirochete. by Marisela M Davis, Aaron M Brock, Tanner G DeHart, Brittany P Boribong, Katherine Lee, Mecaila E McClune, Yunjie Chang, Nicholas Cramer, Jun Liu, Caroline N Jones, Brandon L Jutras

“…In many other Gram-negative bacteria, PG is bound by protein(s), which provide both structural integrity and continuity between envelope layers. …”
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Mitochondrial metabolism and cancer therapeutic innovation by Hongxiang Du, Tianhan Xu, Sihui Yu, Sufang Wu, Jiawen Zhang

“…Their structural complexity enables adaptive responses to diverse physiological demands. …”
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Molecular mechanism of pH sensing and activation in GPR4 reveals proton-mediated GPCR signaling by Chongzhao You, Shimeng Guo, Tianwei Zhang, Xinheng He, Tianyu Gao, Wenwen Xin, Zining Zhu, Yujie Lu, Youwei Xu, Zhen Li, Yumu Zhang, Xi Cheng, Yi Jiang, Xin Xie, H. Eric Xu

“…Abstract Maintaining pH homeostasis is critical for cellular function across all living organisms. Proton-sensing G protein-coupled receptors (GPCRs), particularly GPR4, play a pivotal role in cellular responses to pH changes. …”
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Morphological signs of the prophylactic effect of 1,3-diethylbenzimidazolium triiodide on the ectopic growth of sarcoma 45 in the lung by A. I. Shikhlyarova, L. K. Trepitaki, E. M. Frantsiyants, I. V. Kaplieva, E. M. Nepomnyashchaya, V. A. Bandovkina, I. V. Neskubina, E. I. Surikova

“…It was found out that, instead of the initial acute phase of blood flow reduction due to introduction of tumor cells resulting in neoplastic growth, activation of the immunity cellular link occurred under the influence of 1,3‑diethylbenzimidazolium triiodide along with a compensatory increase in bronchoalveolar structures, regression of tumor nodes and proliferation of connective tissue. …”
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RAB5 is a host dependency factor for the generation of SARS-CoV-2 replication organelles by Yuexuan Chen, Susanne Klute, Konstantin Maria Johannes Sparrer, Ruth Serra-Moreno

“…The successful propagation of SARS-CoV-2 in humans might have been facilitated by usurping evolutionarily conserved cellular factors to execute crucial steps in its life cycle, such as the generation of replication organelles—membrane structures where coronaviruses assemble their replication-transcription complex. …”
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Noncanonical role for the host Vps4 AAA+ ATPase ESCRT protein in the formation of Tomato bushy stunt virus replicase. by Daniel Barajas, Isabel Fernández de Castro Martín, Judit Pogany, Cristina Risco, Peter D Nagy

“…Deletion of Vps4p in yeast leads to the formation of crescent-like membrane structures instead of the characteristic spherule and vesicle-like structures. …”
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Placeholder factors in ribosome biogenesis: please, pave my way by Francisco J. Espinar-Marchena, Reyes Babiano, Jesús de la Cruz

“…The synthesis of cytoplasmic eukaryotic ribosomes is an extraordinarily energy-demanding cellular activity that occurs progressively from the nucleolus to the cytoplasm. …”
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Use of Liquid Nitrogen in Food Products: A Review by Fabiola Pesce, Lucia Parafati, Biagio Fallico, Rosa Palmeri

“…In vegetable products, LN2’s effects depend on cellular structure and water migration. While some studies report losses of polyphenols and flavonoids, others highlight improved vitamin C and antioxidant retention. …”
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Co-translational ribosome pairing enables native assembly of misfolding-prone subunits by Florian Wruck, Jaro Schmitt, Katharina Till, Kai Fenzl, Matilde Bertolini, Frank Tippmann, Alexandros Katranidis, Bernd Bukau, Günter Kramer, Sander J. Tans

“…Abstract Protein complexes are pivotal to most cellular processes. Emerging evidence indicating dimer assembly by pairs of ribosomes suggests yet unknown folding mechanisms involving two nascent chains. …”
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Evolutionary dynamics of predicted G-quadruplexes in human and other great apes by Saswat K. Mohanty, Francesca Chiaromonte, Kateryna D. Makova

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NPI-WGNN: A Weighted Graph Neural Network Leveraging Centrality Measures and High-Order Common Neighbor Similarity for Accurate ncRNA–Protein Interaction Prediction by Fatemeh Khoushehgir, Zahra Noshad, Morteza Noshad, Sadegh Sulaimany

“…Predicting ncRNA–protein interactions (NPIs) is essential for understanding regulatory roles in cellular processes and disease mechanisms, yet experimental methods are costly and time-consuming. …”
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