Comprehensive characterization of poplar HSP20 gene family: genome-wide identification, stress-induced expression profiling, and protein interaction verifications by Lincui Shi, Yude Kang, Ling Ding, Liejia Xu, Xiaojiao Liu, Anmin Yu, Aizhong Liu, Ping Li

“…Abstract Background Heat shock proteins (HSP20s) are crucial components in plant stress responses, acting as molecular chaperones to safeguard cellular integrity and prevent abnormal protein aggregation. …”
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Diverse Roles of the Multiple Phosphodiesterases in the Regulation of Cyclic Nucleotide Signaling in <i>Dictyostelium</i> by Pundrik Jaiswal, Alan R. Kimmel

“…Each PDE has a distinct structure, substrate specificity, regulatory input, cellular localization, and developmentally regulated expression pattern. …”
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SwinCell: a 3D transformer and flow-based framework for improved cell segmentation by Xiao Zhang, Zihan Lin, Liguo Wang, Yong S. Chu, Yang Yang, Xianghui Xiao, Yuewei Lin, Qun Liu

“…Abstract Segmentation of three-dimensional (3D) cellular images is fundamental for studying and understanding cell structure and function. …”
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Genomes of the autonomous parvovirus minute virus of mice induce replication stress through RPA exhaustion. by MegAnn K Haubold, Jessica N Pita Aquino, Sarah R Rubin, Isabella K Jones, Clairine I S Larsen, Edward Pham, Kinjal Majumder

“…The oncolytic autonomous parvovirus Minute Virus of Mice (MVM) establishes infection in the nuclear environment by usurping host DNA damage signaling proteins in the vicinity of cellular DNA break sites. MVM replication induces a global cellular DNA Damage Response (DDR) that is dependent on signaling by the ATM kinase and inactivates the cellular ATR-kinase pathway. …”
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The tumor microenvironment across four dimensions: assessing space and time in cancer biology by Christina R. Larson, Ayushi Mandloi, Satwik Acharyya, Satwik Acharyya, Julienne L. Carstens

“…Common dissociative techniques thoroughly characterize the heterogeneity of cellular populations but lack structural context. The recent boom in spatial analyses has exponentially accelerated our understanding of the structural complexity of these cellular populations. …”
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Interactive proteomics: what lies ahead? by Bernhard Suter, Saranya Kittanakom, Igor Stagljar

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The homodimerization domain of the Stl repressor is crucial for efficient inhibition of mycobacterial dUTPase by Zoé S. Tóth, Ibolya Leveles, Kinga Nyíri, Gergely N. Nagy, Veronika Harmat, Thapakorn Jaroentomeechai, Oliver Ozohanics, Rebecca L. Miller, Marina Ballesteros Álvarez, Beáta G. Vértessy, András Benedek

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Synaptic Functions of Invertebrate Varicosities: What Molecular Mechanisms Lie Beneath by Carlo Natale Giuseppe Giachello, Pier Giorgio Montarolo, Mirella Ghirardi

“…In mammalian brain, the cellular and molecular events occurring in both synapse formation and plasticity are difficult to study due to the large number of factors involved in these processes and because the contribution of each component is not well defined. …”
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Activity-dependent synthesis of Emerin gates neuronal plasticity by regulating proteostasis by Yi Xie, Ruoxi Wang, Daniel B. McClatchy, Yuanhui Ma, Jolene Diedrich, Manuel Sanchez-Alavez, Michael Petrascheck, John R. Yates, III, Hollis T. Cline

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Bright and photostable yellow fluorescent proteins for extended imaging by Jihwan Lee, Shujuan Lai, Shuyuan Yang, Shiqun Zhao, Francisco A. Blanco, Anne C. Lyons, Raquel Merino-Urteaga, John F. Ahrens, Nathan A. Nguyen, Haixin Liu, Zhuohe Liu, Gerard G. Lambert, Nathan C. Shaner, Liangyi Chen, Kimberley F. Tolias, Jin Zhang, Taekjip Ha, François St-Pierre

“…When incorporated into fluorescence resonance energy transfer (FRET)-based biosensors, the proposed YFPs enable more reliable, prolonged imaging of dynamic cellular processes. Overall, the enhanced photostability of mGold2s and mGold2t enables high-sensitivity imaging of subcellular structures and cellular activity over extended periods, broadening the scope and precision of biological imaging.…”
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Исследование белков воспаленной пульпы временных зубов в начальной стадии резорбции корней

“…Cages of the inflamed pulp of a deciduous teeth in an initial stage resorbtive of root take active part in the programmed destruction of a tooth and much less react to development of an inflammation which is characterised by irreversible damage endotelium vessels, suppression of processes of restoration of cellular structures against activation of the proteins participating in apoptosis of cages and destruction of bone structures periodontis.…”
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Shikonin Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis to Attenuate Renal Ischemia/Reperfusion Injury by Activating the Sirt1/Nrf2/HO-1 Pathway by Qian Huang, Zilu Shi, Dandan Zheng, Huiqin Chen, Qiuhong Huang

“…Methods: Renal tissues and blood were collected from experimental renal I/R injury models. Kidney functions, structural injuries, and cellular death were assessed. …”
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Human glycogenins maintain glucose homeostasis by regulating glycogen metabolism by Tzu-Han Weng, Yu-Chung Pien, Ching-Jou Chen, Po-Pang Chen, Yu-Ting Tseng, Ying-Chen Chen, Wen-Po Hsiao, Ying-Ting Lee, Yi-An Chen, Yao-Chi Chen, Carmay Lim, Tzu-Han Hsu, Sung-Jan Lin, Hsin-Yung Yen, Kuo-Chiang Hsia, Su-Yi Tsai

“…Here, we uncover the distinct physiological roles of the human glycogenins GYG1 and GYG2 in glycogen synthesis. Through cellular models, structural biology, and biochemical analyses, we demonstrate that, unlike GYG1, GYG2 exhibits minimal autoglycosylation activity and acts as a suppressor of glycogen formation. …”
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Tight Spaces, Tighter Signals: Spatial Constraints as Drivers of Peripheral Myelination by Luca Bartesaghi, Basilio Giangreco, Vanessa Chiappini, Maria Fernanda Veloz Castillo, Martina Monaco, Jean-Jaques Médard, Giovanna Gambarotta, Marco Agus, Corrado Calì

“…Together, these findings highlight how spatial and structural parameters regulate the cellular and molecular events underlying peripheral myelination, offering new physiologically relevant models of myelination and opening new avenues for peripheral nerve repair strategies.…”
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Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography by Vineeta Das, Furu Zhang, Andrew J. Bower, Joanne Li, Tao Liu, Nancy Aguilera, Bruno Alvisio, Zhuolin Liu, Daniel X. Hammer, Johnny Tam

“…Abstract Background In vivo imaging of the human retina using adaptive optics optical coherence tomography (AO-OCT) has transformed medical imaging by enabling visualization of 3D retinal structures at cellular-scale resolution, including the retinal pigment epithelial (RPE) cells, which are essential for maintaining visual function. …”
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Tissue mimicking hydrogel foam materials with mechanical and radiological properties equivalent to human lung by Xiangpeng Li, Jihua Gou, Anand P. Santhanam, Chiranjit Maiti, Olusegun J. Ilegbusi

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The Diverse Pathways for Cell Surface MT1-MMP Localization in Migratory Cells by Hannah Kelly, Masaki Inada, Yoshifumi Itoh

“…MT1-MMP is tightly regulated at different levels, and its localization to leading-edge membrane structures is an essential process for MT1-MMP to promote cellular invasion. …”
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Texture and Color Enhancement Imaging-Assisted Endocytoscopy Improves Characterization of Gastric Precancerous Conditions: A Set of Interesting Comparative Images by Riccardo Vasapolli, Johannes Raphael Westphal, Christian Schulz

“…In the absence of clear mucosal changes observed through white-light imaging (WLI) or virtual chromoendoscopy, endocytoscopy can help unveil the presence of GPC by enabling in vivo assessment of nuclear and cellular structures at ultra-high magnification. Endocytoscopy is typically performed using WLI following dye-based staining of the mucosa. …”
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Effect of Alkylation on the Kinetic Stability of Arsenodiester and Organoarsenicals against Hydrolysis: A Theoretical Study by Boota Singh, Rohan Ranjan Waliya, Sougata Santra, Kousik Giri, Grigory V. Zyryanov

“…Beside this structural similarity, arsenate is not considered by cellular processes to replace phosphate. …”
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Reentrant DNA shells tune polyphosphate condensate size by Ravi Chawla, Jenna K. A. Tom, Tumara Boyd, Nicholas H. Tu, Tanxi Bai, Danielle A. Grotjahn, Donghyun Park, Ashok A. Deniz, Lisa R. Racki

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