Outer membrane tube formation by Francisella novicida involves extensive envelope modifications and is linked with type VI secretion and alterations to the host phagosomal membrane by Maheen Rashid, Shoichi Tachiyama, Shiwei Zhu, Hang Zhao, William D. McCaig, Jingchuan Sun, Huilin Li, Jun Liu, David G. Thanassi

“…These findings reveal the cellular transformations that occur during membrane tubulation by Francisella and provide insights into the function of membrane-derived structures during host-pathogen interactions.IMPORTANCEFrancisella tularensis is an intracellular bacterial pathogen that causes the zoonotic disease tularemia. …”
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Nanotopographical Features of Polymeric Nanocomposite Scaffolds for Tissue Engineering and Regenerative Medicine: A Review by Kannan Badri Narayanan

“…Additionally, these scaffolds with specific surface topographies, such as grooves (linear channels that guide cell alignment), pillars (protrusions), holes/pits/dots (depressions), fibrous structures (mimicking ECM fibers), and tubular arrays (array of tubular structures), are crucial for regulating cell behavior and promoting tissue repair. …”
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A Hybrid 2D/3D Approach for Neural Differentiation Into Telencephalic Organoids and Efficient Modulation of FGF8 Signaling by Michele Bertacchi, Gwendoline Maharaux, Michèle Studer

“…Our protocol combines the speed and reproducibility of 2D induction with the structural and cellular complexity of 3D telencephalic organoids. …”
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Suppressing Tymovirus replication in plants using a variant of ubiquitin. by Anuradha De Silva, Kihun Kim, John Weiland, Jihyun Hwang, Jacky Chung, Higor S Pereira, Trushar R Patel, Joan Teyra, Ankoor Patel, Mohammed M Mira, Mazdak Khajehpour, Melvin Bolton, Claudio Stasolla, Sachdev S Sidhu, Brian L Mark

“…Consistent with our biochemical and structural findings, transgenic expression of UbV3 in the cytosol of A. thaliana suppressed TYMV replication in planta, with the reduction in viral load being correlated to UbV3 expression level. …”
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Sound‐Based Assembly of Magnetically Actuated Soft Robots Toward Enhanced Release of Extracellular Vesicles by Wei Gao, Riccardo Tognato, Micaela Natta, Elena Della Bella, Alessandro Cianciosi, Tiziano Serra

“…Furthermore, the design and assembly of novel actuators with customized shapes as fish‐ and butterfly‐like structures is shown. The fabricated patterns exhibit different modes of motion under the influence of uniform magnetic fields. …”
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Evolutionarily divergent Mycobacterium tuberculosis CTP synthase filaments are under selective pressure by Eric M. Lynch, Yao Lu, Jin Ho Park, Lin Shao, Justin M. Kollman, E. Hesper Rego

“…Through a combination of structural, biochemical, and cellular techniques, we show that polymerization stabilizes the active conformation of the enzyme and resists product inhibition, potentially allowing for the highly localized production of CTP within the cell. …”
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Large-scale predictions of alternative protein conformations by AlphaFold2-based sequence association by Myeongsang Lee, Joseph W. Schafer, Jeshuwin Prabakaran, Devlina Chakravarty, Madeleine F. Clore, Lauren L. Porter

“…These methods often assume that AF2 relies on evolutionary couplings to predict alternative protein conformations, but they perform poorly on fold-switching proteins, which remodel their secondary structures and modulate their functions in response to cellular stimuli. …”
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The Fabrication of a Biomedical Scaffold from Human Placenta by Jassim Khalaf Albozachri, Hameed AL-Timmemi

“…The freeze-drying process of preparing acellular human placenta powder resulted in structures that are made up of highly interconnected, open networks of pores. …”
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Scientific Basis for the Potential Use of Melatonin in Bone Diseases: Osteoporosis and Adolescent Idiopathic Scoliosis by E. J. Sánchez-Barceló, M. D. Mediavilla, D. X. Tan, R. J. Reiter

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Control of epithelial tissue organization by mRNA localization by Devon E. Mason, Thomas D. Madsen, Alexander N. Gasparski, Dong Kong, Neal Jiwnani, Terry Lechler, Jadranka Loncarek, Roberto Weigert, Ramiro Iglesias-Bartolome, Stavroula Mili

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Allosteric modulation of serotonin and dopamine transporters: New insights from computations and experiments by Hoang Nguyen, Mary Hongying Cheng, Ji Young Lee, Shaili Aggarwal, Ole Valente Mortensen, Ivet Bahar

“…Finally, the examination of cross-correlations between structural elements lining the respective sites S1 and S2 point to the crucial role of coupled motions between TM6a and TM10. …”
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Sirtuins: Emergent Players in Tissue and Organ Regeneration by Ayla Kyler Núñez, Claudia Marcela Arenas-Gómez, Belfran Alcides Carbonell Medina

“…Sirtuins are a family of lysine deacetylases that regulate cellular homeostasis and energy sensing. Regeneration is the process that restores structural and functional homeostasis at the cellular, tissue, organ, and appendage levels. …”
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In-cell NMR reveals the first direct observation of endogenous interaction between HIV Tat protein and Tat RNA aptamer in human cells by Omar Eladl

“…Remarkably, we obtained a partial NOE-based assignment of the RNA upon complexation with Tat in living cells—an unprecedented step towards cellular structural biology. Complementary confocal microscopy validated nuclear co-localization, enabling functionally relevant interaction. …”
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Deformation and Energy Absorption Characteristics of Metallic Thin-Walled Tube with Hierarchical Honeycomb Lattice Infills for Crashworthiness Application by Shahrukh Alam, Mohammad Uddin, Colin Hall

“…This paper investigates the axial deformation characteristics and crashworthiness of thin-walled metal tubes (TWT) reinforced with Polyetherketoneketone (PEKK) honeycomb lattice structures consisting of bio-inspired hierarchical cellular topological features. …”
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The Muscle Cells in Pelvic Floor Dysfunctions: Systematic Review by Ana Margarida Vieira, Maria Leonor Faleiro, Miguel Mascarenhas-Saraiva, Sandra Pais

“…Of the 30 articles selected with a total of 5592 women, 15 referred to the analysis of structural muscle defects, which included 3365 participants with urinary incontinence, pelvic organ prolapse, fecal incontinence, cistocele, rectocele, and sexual dysfunction; 10 manuscripts referred to the study of pelvic floor muscle function with a population of 2042 women, such as urinary incontinence, pelvic organ prolapse, fecal incontinence, and sexual dysfunction; and 5 papers evaluated cellular and/or molecular changes affecting the pelvic floor muscles, like urinary incontinence, pelvic organ prolapse, and rectocele, which included a total of 185 participants. …”
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MALDI-TOF mass spectrometric protein profiling of THP-1 cells and their microvesicles by A. V. Korenevsky, Yu. P. Milyutina, M. E. Berezkina, E. P. Alexandrova, O. A. Balabas, K. L. Markova, S. A. Selkov, D. I. Sokolov

“…The smallest functional groups include regulators of cell differentiation and development, proteins participating in immune response and inflammation, cellular receptors and their regulators, transporter and transport regulatory proteins, as well as cell proteins mediating adhesion and matrix structures, processing regulators, proteins of ubiquitin-proteasome system, intracellular signaling, autophagy and exocytosis regulators, chromatin structural proteins, hemostatic regulators, and peptide hormones. …”
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Chalcone constituents pulincisones A-F isolated from Pulicaria incisa with NQO1 inducer activity by Ahmed R. Hamed, Tarik A. Mohamed, Sally A. Abdel-Halim, Mohamed H. Abd El-Razek, Sayed A. El-toumy, Maureen Higgins, Krystyna Skalicka-Woźniak, Albena T. Dinkova-Kostova, Paul W. Paré, Mahmoud M. Sakr, Mohamed-Elamir F. Hegazy

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Shared interactions of six neurotropic viruses with 38 human proteins: a computational and literature-based exploration of viral interactions and hijacking of human proteins in neu... by Elif Asli Ozer, Aleyna Keskin, Yusuf Huseyin Berrak, Fatma Cankara, Fusun Can, Yasemin Gursoy-Ozdemir, Ozlem Keskin, Attila Gursoy, Hale Yapici-Eser

“…Abstract Introduction Viral infections may disrupt the structural and functional integrity of the nervous system, leading to acute conditions such as encephalitis, and neuropsychiatric conditions as mood disorders, schizophrenia, and neurodegenerative diseases. …”
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Histological characteristics of the myocardium of broilers with the use of Nucleostim by Gatiyatullin Ildar, Bazekin George, Dolinin Ilgiz, Skovorodin Evgeniy

“…Special attention is paid to the morphological characteristics of the myocardium of broiler chickens, as well as the effect of the biostimulator Nucleostim on the myocardium at the tissue and cellular levels. Histological studies have shown that the biological stimulator Nucleostim optimizes the structure of the myocardium, prevents the development of disorders of cellular metabolic mechanisms in the organ, leading to the development of structural changes.…”
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Different populations of mouse egg cortical vesicles are responsible for post-fertilization zinc sparks and proteolysis of the zona pellucida by Omar José, Boris Baibakov, Jurrien Dean

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