FtsZ as a novel target for antibiotics development: Promises and challenges by Ming-Wei Wang, Kaini Hang, Wei Han, Xin Li, Qingtong Zhou, Dehua Yang

“…Structural studies, including X-ray crystallography and cryo-electron microscopy, have resolved 97 FtsZ structures revealing conserved polymerization mechanisms and conformational plasticity, as exemplified by extremophile adaptations (e.g., Shewanella benthica from the high-pressure environment of the Mariana Trench's Challenger Deep). …”
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DANGO: An MS data annotation tool for glycolipidomics by Masaaki Matsubara, Mayumi Ishihara, Michael Tiemeyer, Kazuhiro Aoki, René Ranzinger

“…Glycosphingolipid structural diversity arises from heterogeneity in both the glycan and lipid moieties. …”
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Ca2+ signaling in vascular smooth muscle and endothelial cells in blood vessel remodeling: a review by Yoshiaki Suzuki, Wayne R. Giles, Gerald W. Zamponi, Rubii Kondo, Yuji Imaizumi, Hisao Yamamura

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Broadly conserved FlgV controls flagellar assembly and Borrelia burgdorferi dissemination in mice by Maxime Zamba-Campero, Daniel Soliman, Huaxin Yu, Amanda G. Lasseter, Yuen-Yan Chang, Julia L. Silberman, Jun Liu, L. Aravind, Mollie W. Jewett, Gisela Storz, Philip P. Adams

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The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0. by Caroline E Lilley, Mira S Chaurushiya, Chris Boutell, Roger D Everett, Matthew D Weitzman

“…Cellular restriction factors responding to herpesvirus infection include the ND10 components PML, Sp100 and hDaxx. …”
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The dynamic duo: cryo-EM teams up with machine learning to visualize biomolecules in motion by Beatrice Bowlby

“…Cryo-EM has been a key technique in our understanding of biomolecular structures. Now, machine learning techniques are being used to put these structures in motion, revealing dynamic interactions and processes happening on a molecular and cellular level.…”
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A permeability model for hot cracking susceptibility prediction across near-equilibrium to rapid solidification conditions by Zhihang Zhang, Laishan Yang, Han Wang, Fang Han, Jing Yang, Xiaoqing Zhu, Qinghua Li, Chengkun Li, Chengcheng Wang, Zhibo Dong, Lei Wang, Yuanming Liu

“…However, its behavior becomes unknown when cellular dendrites without side arms form under rapid solidification conditions. …”
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Ceramide signaling in immunity: a molecular perspective by Himani Thakkar, Vinnyfred Vincent, Bhagirath Chaurasia

“…Abstract Ceramides are bioactive lipids that play a crucial role in cellular signaling and structural integrity (Nat Rev Mol Cell Biol 19:175-191, 2018). …”
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Regulatory Networks of lncRNAs, miRNAs, and mRNAs in Response to Heat Stress in Wheat (Triticum Aestivum L.): An Integrated Analysis by Dwijesh Chandra Mishra, Sayanti Guha Majumdar, Anuj Kumar, Jyotika Bhati, K. K. Chaturvedi, Ranjeet Ranjan Kumar, Suneha Goswami, Anil Rai, Neeraj Budhlakoti

“…Furthermore, the modeled three-dimensional (3D) structures of hub genes encoding proteins, which had an appropriate range of similarity with solved structures, provided information on their structural roles. …”
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Effect of glycosylation on protein folding: From biological roles to chemical protein synthesis by Chunchun Hao, Qijie Zou, Xuerong Bai, Weiwei Shi

“…Summary: Chemical protein synthesis has become an important tool in biotechnology and synthetic biology for producing proteins with complex structures. However, achieving correct folding in vitro remains a significant challenge. …”
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Physicochemical characterization of different vegetative stages of Ateleia glazioviana by D.E.B. Fronza, E. Boldori, N. Fronza, M.L. Teixeira, R.E. Mendes

“…The results of toxicological tests for the degree of irritation and cellular damage were positive. Due to the structural similarities of these molecules, further analyses are necessary to characterize the compounds more accurately.…”
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Evolution of dislocations during the rapid solidification in additive manufacturing by Lin Gao, Yan Chen, Xuan Zhang, Sean R. Agnew, Andrew C. Chuang, Tao Sun

“…Abstract Materials processed by fusion-based additive manufacturing (AM) typically exhibit relatively high dislocation densities, along with cellular structures and elemental segregation. This representative structural feature significantly influences material performance; however, post-mortem microstructure characterizations of AM materials cannot capture the dynamic evolution of dislocations during the manufacturing process, thereby offering limited mechanism-based guidance for further advancing AM techniques and facilitating the qualification and certification of AM products. …”
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Magnetic Polymeric Conduits in Biomedical Applications by Sayan Ganguly, Shlomo Margel

“…The integration of magnetic nanoparticles into polymeric matrices confers distinctive features, including regulated alignment, improved cellular motility, and targeted medicinal delivery, while preserving structural integrity. …”
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Extracellular Signaling Molecules from Adipose-Derived Stem Cells and Ovarian Cancer Cells Induce a Hybrid Epithelial-Mesenchymal Phenotype in a Bidirectional Interaction by Vinícius Augusto Simão, Juliana Ferreira Floriano, Roberta Carvalho Cesário, Karolina da Silva Tonon, Larissa Ragozo Cardoso de Oliveira, Flávia Karina Delella, Fausto Almeida, Lucilene Delazari dos Santos, Fábio Rodrigues Ferreira Seiva, Débora Aparecida Pires de Campos Zuccari, João Tadeu Ribeiro-Paes, Russel J. Reiter, Luiz Gustavo de Almeida Chuffa

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Ligand presentation controls collective MSC response to matrix stress relaxation in hybrid PEG-HA hydrogels by Alexandra N. Borelli, Courtney L. Schultze, Mark W. Young, Bruce E. Kirkpatrick, Kristi S. Anseth

“…Cellular interactions with the material were controlled through peptides to present integrin binding ECM cues (RGD) or cadherin binding cell-cell cues (HAVDI) and MSCs were observed to form highly elongated structures in RGD containing hydrogels (α=0.56±0.05), whereases collapsed structures were observed within HAVDI containing hydrogels (α=0.39±0.04). …”
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Microtubules as a versatile reference standard for expansion microscopy by Rajdeep Chowdhury, Tiago Mimoso, Abed Alrahman Chouaib, Nikolaos Mougios, Donatus Krah, Felipe Opazo, Sarah Köster, Silvio O. Rizzoli, Ali H. Shaib

“…Abstract Expansion microscopy (ExM) is continually improving, and new ExM variants need to be validated on well-defined biological structures. There is no consensus on validation structures for ExM, especially as nuclear pore complexes or DNA nanorulers are not popular for ExM studies. …”
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Bioinspired piezoelectric patch design for sonodynamic therapy: a preclinical mechanistic evaluation of rotator cuff repair and functional regeneration by Rui Shi, Rui Shi, Fei Liu, Qihuang Qin, Pinxue Li, Ziqi Huo, You Zhou, Chunyan Jiang

“…Piezoelectric materials, known for modulating cellular functions and promoting stem cell proliferation and differentiation, have garnered increasing attention in tissue repair applications.MethodsIn this study, a biomimetic piezoelectric patch with progressive compositional and structural variations was designed and fabricated. …”
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The Role of (Nuclear) Lipid Droplets in the Pathogenesis of Metabolic Syndrome by Natalia Todosenko, Kristina Yurova, Olga Khaziakhmatova, Maria Vulf, Vladimir Malashchenko, Aleksandra Komar, Ivan Kozlov, Igor Khlusov, Larisa Litvinova

“…Metabolic syndrome (MetS) is a widespread multi-component pathological condition characterized by meta-inflammation and cellular dysfunction. MetS and other metabolic diseases (metabolic dysfunction-associated steatotic liver disease (MASLD), cardiovascular-kidney-metabolic syndrome (CKMS)) stem from the disorder of energy metabolism and changes in the structure and function of specialized organelles such as lipid droplets, endoplasmic reticula, mitochondria, and nuclei. …”
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Effect of Ionic Strength on Porphyrin Drugs Interaction with Quadruplex DNA Formed by the Promoter Region of C-myc and Bcl2 Oncogenes by Narayana Nagesh, Varun K. Sharma, A. Ganesh Kumar, Edwin A. Lewis

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Super-resolution imaging strategies for cell biologists using a spinning disk microscope. by Neveen A Hosny, Mingying Song, John T Connelly, Simon Ameer-Beg, Martin M Knight, Ann P Wheeler

“…Through comparative studies with structured illumination microscopy (SIM) and widefield epifluorescence imaging we identified that our methodology was advantageous for imaging cellular structures which are not immediately at the cell-substrate interface, which include the nuclear architecture and mitochondria. …”
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