Src kinase conformational activation: thermodynamics, pathways, and mechanisms. by Sichun Yang, Benoît Roux

“…Tyrosine kinases of the Src-family are large allosteric enzymes that play a key role in cellular signaling. Conversion of the kinase from an inactive to an active state is accompanied by substantial structural changes. …”
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Lasting Differential Effects on Plasticity Induced by Prenatal Stress in Dorsal and Ventral Hippocampus by Gayane Grigoryan, Menahem Segal

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Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines by Lee Sherry, Mohammad W. Bahar, Claudine Porta, Helen Fox, Keith Grehan, Veronica Nasta, Helen M. E. Duyvesteyn, Luigi De Colibus, Johanna Marsian, Inga Murdoch, Daniel Ponndorf, Seong-Ryong Kim, Sachin Shah, Sarah Carlyle, Jessica J. Swanson, Sue Matthews, Clare Nicol, George P. Lomonossoff, Andrew J. Macadam, Elizabeth E. Fry, David I. Stuart, Nicola J. Stonehouse, David J. Rowlands

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Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE by Yaqi Liu, Chelsea M. Brown, Nuno Borges, Rodrigo N. Nobre, Satchal Erramilli, Meagan Belcher Dufrisne, Brian Kloss, Sabrina Giacometti, Ana M. Esteves, Cristina G. Timóteo, Piotr Tokarz, Rosemary J. Cater, Todd L. Lowary, Yasu S. Morita, Anthony A. Kossiakoff, Helena Santos, Phillip J. Stansfeld, Rie Nygaard, Filippo Mancia

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The topological properties of the protein universe by Christian D. Madsen, Agnese Barbensi, Stephen Y. Zhang, Lucy Ham, Alessia David, Douglas E. V. Pires, Michael P. H. Stumpf

“…Abstract Deep learning methods have revolutionised our ability to predict protein structures, allowing us a glimpse into the entire protein universe. …”
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Hinged plakin domains provide specialized degrees of articulation in envoplakin, periplakin and desmoplakin. by Caezar Al-Jassar, Pau Bernadό, Martyn Chidgey, Michael Overduin

“…This establishes specialised hinges in plakin domains as a key source of flexibility that may allow sweeping of cellular spaces during assembly of cellular structures and could impart adaptability, so preventing irreversible damage to desmosomes and the cell cytoskeleton upon exposure to mechanical stress.…”
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Production of an immunogenic trivalent poliovirus virus-like particle vaccine candidate in yeast using controlled fermentation by Lee Sherry, Keith Grehan, Mohammad W. Bahar, Jessica J. Swanson, Helen Fox, Sue Matthews, Sarah Carlyle, Ling Qin, Claudine Porta, Steven Wilkinson, Suzanne Robb, Naomi Clark, John Liddell, Elizabeth E. Fry, David I. Stuart, Andrew J. Macadam, David J. Rowlands, Nicola J. Stonehouse

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Molecular simulation study of RNA/dopamine complex dynamics at varying concentrations by Armen H. Poghosyan, Yevgeni S. Mamasakhlisov, Marine A. Parsadanyan, Mariam A. Shahinyan, Zvart H. Movsisyan, Poghos O. Vardevanyan

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Magnetically Induced Anisotropic Microstructures on Polyethylene Glycol Hydrogel Facilitate BMSC Alignment and Osteogenic Differentiation by Hua Zhang, Yang Luo, Rong Xu, Xu Cao, Guanrong Li, Shang Chen

“…Many tissues exhibit structural anisotropy, which imparts orientation-specific properties and functions. …”
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Mapping Hsp104 interactions using cross‐linking mass spectrometry by Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak

“…Recent cryo‐EM structures of AAA+ molecular machines have uncovered nuanced changes in their conformation that underlie their specialized functions. …”
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Nested U-Net-Based GAN Model for Super-Resolution of Stained Light Microscopy Images by Seong-Hyeon Kang, Ji-Youn Kim

“…In particular, the intensity profile analysis confirmed the effectiveness of the nested U-Net-based generator in restoring cellular boundaries and structures in the stained microscopy images. …”
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Study on diffusion bonding of composite metal foams by John Cance, Afsaneh Rabiei

“…Solid-state joining processes are particularly well-suited for metal foams as they can form solid bonds between porous workpieces without distorting their cellular structures. Previous success was achieved in joining CMF panels up to 2.5 cm thick through induction welding, though localized heating through induced Eddy currents could not fully permeate thicker samples. …”
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SuperResNET: Model‐Free Single‐Molecule Network Analysis Software Achieves Molecular Resolution of Nup96 by Yahongyang Lydia Li, Ismail M. Khater, Christian Hallgrimson, Ben Cardoen, Timothy H. Wong, Ghassan Hamarneh, Ivan R. Nabi

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Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1 by Qinyu Zhu, Madeleine F. Yaggi, Nikolaus Jork, Henning J. Jessen, Melinda M. Diver

“…Abstract Inorganic phosphate (Pi) has essential metabolic and structural roles in living organisms. The Pi exporter, XPR1/SLC53A1, is critical for cellular Pi homeostasis. …”
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Exploring the potential of in-situ foam 3D printing: Effects of printing parameters and the development of functionally graded foams by Viktória Kunsági, Péter Széplaki, Márton Tomin

“…In this study, we investigated the influence of processing parameters on the cellular structure and density of specimens fabricated using in-situ foam 3D printing. …”
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Versatility of vimentin assemblies: From filaments to biomolecular condensates and back by Dolores Pérez-Sala, Silvia Zorrilla

“…Cytoskeletal structures shape and confer resistance to cells. The intermediate filament protein vimentin forms versatile structures that play key roles in cytoskeletal crosstalk, in the integration of cellular responses to a variety of external and internal cues, and in the defense against stress. …”
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HISTOGENETIC ASPECTS OF PNEUMOFIBROSIS DURING CONIOTIC CHANGES IN KUZBASS MINERS by Олег Иванович Бондарев, Сергей Николаевич Филимонов

“…Morphometry was performed in structures without signs of traumatic effects. Results. …”
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The Smc5/6 complex counteracts R-loop formation at highly transcribed genes in cooperation with RNase H2 by Shamayita Roy, Hemanta Adhikary, Sarah Isler, Damien D'Amours

“…Here, we show that a core regulator of chromosome architecture —the Smc5/6 complex— plays a crucial role in the removal of R-loop structures formed during gene transcription. Consistent with this, budding yeast mutants defective in the Smc5/6 complex and enzymes involved in R-loop resolution show strong synthetic interactions and accumulate high levels of RNA-DNA hybrid structures in their chromosomes. …”
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Morphology of autolymphocytes used in the treatment of trophic ulcers in the setting of diabetic foot syndrome by M. S. Lyubarsky, O. A. Shoumkov, D. V. Khabarov, N. P. Bgatova, O. V. Kamenskaya

“…Thus, technologies of autolymphocytes iden-tification do not result to damaged structure of cells. Processing of the lymphocytes by leukinoferon does not cause cellular damage but promotes development of structural changes.…”
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Temporally and Spatially Controlled Age-Related Prostate Cancer Model in Mice by Sen Liu, Keyi Shen, Zixuan Li, Seleste Rivero, Qiuyang Zhang

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