Isolation and pathogenicity of the novel porcine reproductive and respiratory syndrome virus 1 strain ZJ01 in South China by Bohua Ren, Ruying Liu, Feibao Huang, Yu Wu, Yu Wu, Xiaopeng Gao, Haishen Zhao, Limiao Lin, Qunhui Li, Qunhui Li, Xiangbin Zhang

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In vitro impact of Streptococcus mitis on the inhibition of oral cancer cell proliferation via mitotic modulation by Inori Inui, Inori Inui, Shinichi Mochizuki, Fumika Hirabayashi-Nishimuta, Yoshie Yoshioka, Osamu Takahashi, Masaaki Sasaguri, Manabu Habu, Wataru Ariyoshi, Ryota Yamasaki, Ryota Yamasaki

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Eco-friendly silver nanoparticles from garlic: a novel therapeutic approach for treating Escherichia fergusonii wound infections by Sozan M. Abdelkhalig, Arwa Gamal Ali, Mohamed Farouk Ghaly, Nada K. Alharbi, Maha Alharbi, Mahmoud M. Bendary, Amira I. Abousaty

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Evolution, dissemination, and genetic dynamics of the carbapenem resistance gene blaNDM in China by Xiaofeng Hu, Boqian Wang, Mingliang Chen, Mingliang Chen, Mingliang Chen, Kexin Li, Kexin Li, Zhixi Peng, Zhixi Peng, Lianqun Jin, Junjie Yue, Hui Chen, Ling Zhang, Shaofu Qiu, Hongguang Ren, Hongbin Song

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Overcoming beta-lactam resistance in Pseudomonas aeruginosa by targeting metallo-beta-lactamase VIM-1: a one-microsecond molecular dynamics simulation study by Mohammed Salleh M. Ardawi, Samar A. Badreddine, Muhammad Yasir, Muhammad Yasir, Aiah M. Khateb, Aiah M. Khateb, Safaa A. Turkistani, Ahmed Afandi, Samah O. Noor, Adhari Alselmi, Adhari Alselmi, Vivek Dhar Dwivedi, Vivek Dhar Dwivedi, Esam I. Azhar, Esam I. Azhar

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Overexpression in Plasmodium falciparum of an intrinsically disordered protein segment of PfUT impairs the parasite’s proteostasis and reduces its growth rate by Yunuen Avalos-Padilla, Yunuen Avalos-Padilla, Inés Bouzón-Arnáiz, Inés Bouzón-Arnáiz, Miriam Ramírez, Claudia Camarero-Hoyos, Claudia Camarero-Hoyos, Claudia Camarero-Hoyos, Marc Orozco-Quer, Elsa M. Arce, Diego Muñoz-Torrero, Diego Muñoz-Torrero, Xavier Fernàndez-Busquets, Xavier Fernàndez-Busquets, Xavier Fernàndez-Busquets

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ZIKV prM hijacks PIM1 kinase for phosphorylation to prevent ubiquitin−mediated degradation and facilitate viral replication by Yingying Ren, Yingying Ren, Yishuo Liu, Rui Pang, Gang Xu, Yining Lei, Yining Lei, Hang Fai Kwok, Yingliang Wu, Zhijian Cao, Zhijian Cao, Zhijian Cao, Zhijian Cao

“…Co-immunoprecipitation and GST pull-down assays revealed that the ZIKV structural protein precursor membrane (prM) interacted with PIM1. …”
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Viable but nonculturable state in the zoonotic pathogen Bartonella henselae induced by low-grade fever temperature and antibiotic treatment by Yuze Gou, Yuze Gou, Dongxia Liu, Dongxia Liu, Yuxian Xin, Yuxian Xin, Ting Wang, Jiaxin Li, Yiwen Xi, Xiaoling Zheng, Tuanjie Che, Ying Zhang, Ying Zhang, Tingting Li, Jie Feng, Jie Feng

“…Transmission electron microscopy (TEM) examination revealed intact cell structures and dense cytosol in VBNC cells, with a significant increase in plasmolytic cells. …”
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Stool carriage of CTX-M/CMY-producing Salmonella enterica in a Chinese tertiary hospital in Shenzhen, China by Jing Wang, Jing Wang, Zi-Han Dong, Xian-Yuan Zhou, Qin-Chun Ma, Zhen-Yu Wang, Dachuan Lin, Ying-Feng Huang, Chi Zhang, Xinan Jiao, Deng Li, Qiuchun Li

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A flexible peptide linking the periplasmic and cytoplasmic domains of MxiG controls type III secretion signaling and stable sorting platform assembly in Shigella by Shoichi Tachiyama, Shoichi Tachiyama, Meena Muthuramalingam, Sean K. Whittier, Sean K. Whittier, Yunjie Chang, Yunjie Chang, Jian Yue, Jian Yue, Waleed Younis, Waleed Younis, Waleed Younis, Wendy L. Picking, Wendy L. Picking, Jun Liu, Jun Liu, William D. Picking, William D. Picking

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Fecal microbiota transplantation alleviates lipopolysaccharide-induced osteoporosis by modulating gut microbiota and long non-coding RNA TUG1 expression by Pengcheng Ma, Ruoyi Wang, Huizhi Chen, Jiachun Zheng, Weijie Yang, Bo Meng, Yifan Liu, Yao Lu, Jing Zhao, Hongwei Gao, Hongwei Gao

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Screening and identification of protein 29 of Echinococcus granulosus interacting molecules by Zailing Shang, Fei Qiao, Yaning Li, Xuelin Ma, Mingxia Wang, Wenji Yang, Tianyu He, Haixia Ma, Yana Wang, Yana Wang

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A Reflux Linked GATA Factor Fulcrum Dictates Lineage Commitment Through GPRC5B During the Esophageal Dysplastic TransitionSummary by Omar Abuhussein, Sara Hosseini-Farahabadi, Corina Stewart, Stephane Flibotte, Alireza Heravi-Moussavi, David Farnell, David Schaeffer, Fergal Donnellan, Frank McKeon, Wa Xian, Dermot Kelleher, Shane Patrick Duggan

“…Using an organ-on-a-chip platform, cellular overgrowth, reduced luminal villus structures, lower goblet cell numbers, and loss of intestine-associated marker gene expression (TFF3/MUC2) were observed following GPRC5B overexpression in BE-ASCs, mirroring HGD. …”
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The oncolytic avian reovirus p17 protein suppresses invadopodia formation via disruption of TKs5 complexes and oncogenic signaling pathways by Chao-Yu Hsu, Jyun-Yi Li, Jyun-Yi Li, Wei-Ru Huang, Wei-Ru Huang, Tsai-Ling Liao, Tsai-Ling Liao, Hsiao-Wei Wen, Chi-Young Wang, Chi-Young Wang, Lon-Fye Lye, Brent L. Nielsen, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu

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Epidemiological, clinical, and molecular analysis of human adenovirus infections in hospitalized children with acute respiratory infections in Tianjin, China by Yulian Fang, Yulian Fang, Min Lei, Min Lei, Lu Zhang, Mengzhu Hou, Mengzhu Hou, Ning Wang, Ning Wang, Chunquan Cai, Chunquan Cai

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The intestinal microbiota modulates the visceral sensitivity involved in IBS induced by restraint combined with tail clustering by Na Deng, Na Deng, Siqin Xie, Qin Liu, Huiyi Peng, Leyao Fang, Junxi Shen, Xiaoyuan Lin

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A “proto” type galectin expressed in striped bass (Morone saxatilis) tissues is released to epidermal mucus and binds to bacterial and mucus glycans by Davin E. Henrikson, Davin E. Henrikson, Hafiz Ahmed, Hafiz Ahmed, Satoshi Tasumi, Satoshi Tasumi, Mahesh Gokara, Chiguang Feng, Chiguang Feng, Kelsey Abernathy, Kelsey Abernathy, Muddassar Iqbal, Muddassar Iqbal, Mario A. Bianchet, Gerardo R. Vasta, Gerardo R. Vasta

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Chloroquine induces eryptosis in P. falciparum-infected red blood cells and the release of extracellular vesicles with a unique protein profile by Claudia Carrera-Bravo, Claudia Carrera-Bravo, Tianchi Zhou, Tianchi Zhou, Trang Chu, Jing Wen Hang, Harshvardhan Modh, Chenyuan Huang, Chenyuan Huang, Sitong Zhang, Sitong Zhang, Haining Hao, Haining Hao, Haining Hao, María José Cabada-García, Benoit Malleret, Benoit Malleret, Matthias G. Wacker, Jiong-Wei Wang, Jiong-Wei Wang, Jiong-Wei Wang, Jiong-Wei Wang, Laurent Rénia, Kevin S. W. Tan

“…Notably, the outward budding and blebbing of the iRBC plasma membrane led to the formation of EVs, which are complex structures with unique functional properties. Proteomic characterization of EVs from CQ-treated iRBCs revealed a high enrichment of proteasome and ribosome protein clusters. …”
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Unraveling the Oncogenic Characteristics of the Cytolinker, Plectin, in Esophageal Squamous Cell CarcinomaSummary by Lili Qiao, Yuanyuan Hu, Lei Xu, Guodong Deng, Xiaohong Yu, Wei Zheng, Yanan Yang, Hui Yuan, Wei Jiang, Xiying Yu

“…Background & Aims: Tissue mechanics involved in carcinogenesis by regulating cell morphology and structure, cell-cell, and cell-extracellular matrix (ECM) interactions are not fully understood. …”
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Tracing the evolutionary trajectory of the IncP-2 plasmid co-harboring blaIMP-45 and blaVIM-1: an outbreak of Pseudomonas aeruginosa co-producing IMP-45 and VIM-1 carbapenemases in... by Yiqun Ma, Yiqun Ma, Yiqun Ma, Zichen Lei, Zichen Lei, Zichen Lei, Yulin Zhang, Yulin Zhang, Qi Liu, Qi Liu, Qi Liu, Feilong Zhang, Feilong Zhang, Feilong Zhang, Hao Zu, Xinrui Yang, Xinrui Yang, Xinrui Yang, Ziyao Li, Ziyao Li, Ziyao Li, Binghuai Lu, Binghuai Lu, Binghuai Lu, Binghuai Lu, Binghuai Lu

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