Deep learning for computational biology by Christof Angermueller, Tanel Pärnamaa, Leopold Parts, Oliver Stegle

“…Abstract Technological advances in genomics and imaging have led to an explosion of molecular and cellular profiling data from large numbers of samples. …”
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Peroxiredoxin 6 in Stress Orchestration and Disease Interplay by Jiangfeng Liao, Yusi Zhang, Jianwei Yang, Longfei Chen, Jing Zhang, Xiaochun Chen

“…Additionally, certain stressors, including reactive oxygen species, pH fluctuations, and post-translational modifications, induced the structure-based functional switches in the PRDX6 enzyme. …”
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Effect of intercellular collisions on red blood cell membrane damage by Hristo Valtchanov, Renzo Cecere, Rosaire Mongrain

“…Abstract Modelling blood flow and particularly cellular damage induced by supra- and non-physiological blood-flow conditions is crucial when developing novel blood-exposed biomedical devices and treatments. …”
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Non‐genetic diversity modulates population performance by Adam James Waite, Nicholas W Frankel, Yann S Dufour, Jessica F Johnston, Junjiajia Long, Thierry Emonet

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Continuous Fabrication Process of Aluminum Foam from Foaming to Press Forming by Yoshihiko Hangai, Yuito Kaneko, Kenji Amagai

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Analysis of Nicotine Toxicity and Mechanisms of Senescence in Nucleus Pulposus Cells Using Network Toxicology and Molecular Docking Technique by Chen Jiang, Chao Song, Chaoqi Chen, Baoxin Shen, Lei Yang, Chi Zhang, Fei Liu, Xiaofei Wu, Feng Chen

“…ABSTRACT Aim Through the use of network toxicology, the research sought to determine whether cellular senescence and associated molecular mechanisms in nicotine‐induced intervertebral disc degeneration (IVDD) were potentially harmful. …”
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Discovery and biological evaluation of a novel and highly potent JAK2 inhibitor for the treatment of triple negative breast cancer by Yingxiang Miao, Shudan Yang, Fang Zhang, Jindong Li, Yan Zhang

“…Herein, we discovered six JAK2 inhibitors using structure-based virtual screening and molecular docking. …”
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The N-formyl peptide receptors: much more than chemoattractant receptors. Relevance in health and disease by Filomena Napolitano, Nunzia Montuori, Nunzia Montuori

“…Pattern Recognition Receptors (PRRs) are a superfamily of receptors that detect molecular structures typical for pathogens and damaged cells and play a crucial role in the proper function of the innate immune system. …”
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Bond slip behavior of light steel and foamed concrete under freeze-thaw cycles by Minghao Yang, Qiang Xu, Hai Yuan, Shuwang Yang, Yongbiao Jiang, Chen Zhang, Yingdong Xu, Chenhao Su, Zhiyuan Zhang

“…Abstract The light steel-foamed concrete composite structure is mainly used in residential building walls and light industrial plant enclosures. …”
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Formation mechanism of serrated grain boundary caused by different morphologies of γ′ precipitates in GH4742 superalloy by Qiang Tian, Wenwen Zhang, Hucheng Li, Yunlong Liu, Tonggang Lu, Jinhui Du, Xingang Liu, Kaiyao Wang

“…However, when the cooling rate drops below 120 °C/h, the growth mechanism becomes dominant, leading to larger cellular structures and more twisted serrated grain boundaries. …”
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In silico molecular studies of Phosphinogold(I) thiocarbohydrate complexes: insights into multi-target anticancer mechanisms by Alkhair Adam Khalil Mohamed, Isaac Asiamah, Ghazi Elamin, James Darkwa, Christian K. Adokoh

“…Binuclear complexes' superior affinities for DNMT1 and HDM2 suggest structural advantages for multi-target inhibition.Conclusion:The paradoxical effect of acetylation underscores the importance of balancing lipophilicity and binding strength in ligand design.…”
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Cardiac diffusion-weighted and tensor imaging: A consensus statement from the special interest group of the Society for Cardiovascular Magnetic Resonance by Erica Dall’Armellina, Daniel B. Ennis, Leon Axel, Pierre Croisille, Pedro F. Ferreira, Alexander Gotschy, David Lohr, Kevin Moulin, Christopher T. Nguyen, Sonja Nielles-Vallespin, William Romero, Andrew D. Scott, Christian Stoeck, Irvin Teh, Elizabeth M. Tunnicliffe, Magalie Viallon, Victoria Wang, Alistair A. Young, Jürgen E. Schneider, David E. Sosnovik

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Microstructure simulation of maraging steel 1.2709 processed by powder bed fusion of metals using a laser beam: A cellular automata approach with varying process parameters by Kai-Uwe Beuerlein, Mohammad Shojaati, Mazyar Ansari, Hannes Panzer, Shahriar Imani Shahabad, Mohsen K. Keshavarz, Michael F. Zaeh, Saeed Maleksaeedi

“…In this manufacturing process, a grain structure that is very sensitive to process parameter modifications and the resulting change in the temperature field is formed. …”
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Site‐Specific Disulfide‐Mediated Crosslinking of DNA Nanocubes for Enhanced Biological Applications by Sinan Faiad, Quentin Laurent, Jathavan Asohan, Tyler Brown, Alexander Prinzen, Hanadi Farouk Sleiman

“…With nearly quantitative crosslinking yields, the structure retains its structural integrity in conditions that mimic physiological environments. …”
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Evaluation of the Influence of Wind-Induced Dune Movement on Transmission Tower Lines by Shijun Wang, Wenyuan Bai, Yunfei Tian, Hailong Zhang, Hongchao Dun

“…As wind velocities wane, the structural integrity of the transverse dunes is compromised, leading to an expansion in the size of the trail structures. …”
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Targeted photodynamic therapy: enhancing efficacy through specific organelle engagement by Jiawen Tao, Zhifei Yuan, Mengjiao Zhou

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Quantum magnetization exchange through transient hydrogen bond matrix defines magnetic resonance signal relaxation and anisotropy in central nervous system by Dmitriy A. Yablonskiy, Alexander L. Sukstanskii

“…Abstract The integrity of cellular membranes (lipid bilayers) and myelin sheaths covering axons is a crucial feature controlling normal brain structural and functional networks. …”
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Glycine betaine in plant responses and tolerance to abiotic stresses by Afsana Jarin, Uttam Kumar Ghosh, Md. Saddam Hossain, Apple Mahmud, Md. Arifur Rahman Khan

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Novel dual gland GAN architecture improves human protein localization classification using salivary and pituitary gland inspired loss functions by Hanaa Salem Marie, Moatasem M. Draz, Waleed Abd Elkhalik, Mostafa Elbaz

“…Our method introduces the “Salivary Gland” loss function (SG-Loss), which addresses missing pixel imputation through a unique computational mechanism that models the graded secretion patterns of acinar cells, incorporating multi-scale contextual information to reconstruct incomplete cellular features. This is paired with our innovative “Pituitary Gland” loss function (PG-Loss), which preserves structural integrity through a novel homeostatic regularization approach that adaptively weights pixel relationships based on subcellular compartment boundaries, unlike conventional smoothing techniques. …”
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Total cell N-glycosylation is altered during differentiation of induced pluripotent stem cells to neural stem cells and is disturbed by trisomy 21 by Ana Cindrić, Frano Vučković, Aoife Murray, Thomas S. Klarić, Ivan Alić, Jasminka Krištić, Dean Nižetić, Gordan Lauc

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