Dual EMCV-IRES-integrated dengue virus can express an exogenous gene and cellular Mdm2 integration suppresses the dengue viral replication by Tadahisa Teramoto

“…An IRES sequence derived from encephalomyocarditis (EMCV) was inserted into dengue virus serotype 2 (DENV2); a non-structural (NS) polyprotein was translated by IRES separately from 5′ cap-induced structural polyprotein translation. …”
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Short- and long-range cis interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis. by Ian J Groves, Emma L A Drane, Marco Michalski, Jack M Monahan, Cinzia G Scarpini, Stephen P Smith, Giovanni Bussotti, Csilla Várnai, Stefan Schoenfelder, Peter Fraser, Anton J Enright, Nicholas Coleman

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Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection. by Kamal L Nahas, Viv Connor, Katharina M Scherer, Clemens F Kaminski, Maria Harkiolaki, Colin M Crump, Stephen C Graham

“…To protect the near-native structure of cellular compartments we used a non-disruptive sample preparation technique involving rapid cryopreservation, and a fluorescent reporter virus was used to facilitate correlation of structural changes with the stage of infection in individual cells. …”
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A spatial hierarchical learning module based cellular automata model for simulating urban expansion: case studies of three Chinese urban areas by Xiaoyong Tan, Min Deng, Kaiqi Chen, Yan Shi, Bingbing Zhao, Qinghao Liu

“…However, they suffered from complex structural information inherent in neighborhood effects, including spatio-temporal dimension disjunction and neighborhood sensitivity. …”
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The use of biocompatible composite scaffolds in oncology by O. I. Kit, A. Yu. Maksimov, I. A. Novikova, A. S. Goncharova, E. A. Lukbanova, A. O. Sitkovskaya, V. G. Volovik, S. V. Chapek

“…A review of studies devoted to the development of three-dimensional composite structures (scaffolds) and their application in the field of cellular technologies was carried out. …”
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Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men by Nina Le Bert, Wan Ni Chia, Wei Yee Wan, Alvin Kuo Jing Teo, Samuel Zeng-Rong Chong, Nicole Tan, Doreen Soek Chin Tan, Adeline Chia, Iain Beehuat Tan, Kamini Kunasegaran, Qin Xuan Chua, Mohammad Yazid Abdad, Aven Shan Hua Ng, Shawn Vasoo, Julian Xiao-Li Ang, Mao Sheng Lee, Louisa Sun, Jinyan Fang, Feng Zhu, Alex R. Cook, Tar Choon Aw, Jingxiang Huang, Clarence Tam, Fong Sin Lee, Hannah Clapham, Enan Jun-Kang Goh, Monica Socheata Suor Peou, Shiow Pin Tan, Siew Kim Ong, Lin-Fa Wang, Antonio Bertoletti, Li Yang Hsu, Biauw Chi Ong

“…Background: We studied humoral and cellular responses against SARS-CoV-2 longitudinally in a homogeneous population of healthy young/middle-aged men of South Asian ethnicity with mild COVID-19. …”
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CHOICE THEORY OF CREEP DEFORMATION FOR EVALUATION OF LONG FINE-GRAINED AUTOCLAVED AERATED CONCRETE IN VIEW OF FACTORS CARBONIZATION by D. K-S. Bataev, M. A. Gaziev, H. N. Majiev

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Genetic and Cellular Basis of Resistance to Black Rot Caused by <i>Xanthomonas campestris</i> pv. <i>campestris</i> in <i>Brassica rapa</i> by Siping Deng, Congcong Kong, Hongxue Ma, Jialei Ji, Yong Wang, Yangyong Zhang, Mu Zhuang, Limei Yang, Zhiyuan Fang, Vasiliy Taranov, Anna M. Artemyeva, Honghao Lv

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Those magnificent pathologists and their computational machines by Gil Patrus Mundim Pena

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Pathological and Inflammatory Consequences of Aging by Mario García-Domínguez

“…Aging is a complex, progressive, and irreversible biological process that entails numerous structural and functional changes in the organism. These changes affect all bodily systems, reducing their ability to respond and adapt to the environment. …”
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Enhancing Neural Network Training Through Neuroevolutionary Models: A Hybrid Approach to Classification Optimization by Hyasseliny A. Hurtado-Mora, Luis A. Herrera-Barajas, Luis J. González-del-Ángel, Roberto Pichardo-Ramírez, Alejandro H. García-Ruiz, Katea E. Lira-García

“…This research proposes a hybrid neuroevolutionary approach that integrates a genetic algorithm with a NEAT-based structure to enhance ANN performance. Additionally, a Cellular Processing Algorithm (PCELL) is employed to expand the search space and improve solution quality. …”
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Mechanosensitive Piezo channels in mineralized tissues: emerging roles in osteodental adaptation and disease by Junchi Dong, Ran Li, Yuhuang Chen, Guixin Zhu, Xing Liang

“…This review consolidates recent advances in Piezo channel biology, clarifying their structural properties, tissue-specific distribution, and functional roles in mineralized tissues. …”
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GAG Protein of <i>Arabidopsis thaliana</i> LTR Retrotransposon Forms Retrosome-like Cytoplasmic Granules and Activates Stress Response Genes by Alexander Polkhovskiy, Roman Komakhin, Ilya Kirov

“…LTR retrotransposons are widespread genomic elements that significantly impact genome structure and function. In <i>Arabidopsis thaliana</i>, the EVD LTR retrotransposon encodes a GAG protein essential for retrotransposon particle assembly. …”
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FEATURES OF CLINICAL DISPLAYS OF THE TRANSPLANTED HEART ACUTE REJECTION by S. J. Shemakin, A. J. Kormer, T. A. Khalilulin, V. V. Chestuhin, I. M. Iljinsky, A. G. Kuprijanova

“…In the present research features of current of clinical and structural changes are considered at acute rejection at the patients who have carried orthotopic transplantation of heart. …”
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Umbilical cord and cord blood cells promising for biobanking by V. V. Chrishtop, M. I. Lobanova, R. I. Glushakov, A. A. Semenov, D. V. Ovchinnikov, A. V. Anisin

“…The high demand for biobanking of umbilical cord and cord blood has led to the emergence of specialized structures – Umbilical Cord Blood Banks. The aim was to systematize the literature data on the cellular composition of the umbilical cord and umbilical cord blood as an object of biobanking. …”
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Targeted Inhibition of cGAS/STING signaling induced by aberrant R-Loops in the nucleus pulposus to alleviate cellular senescence and intervertebral disc degeneration by Dan Wu, Chen Yan, Linhui Han, Fudong Li, Ximing Xu, Jingchuan Sun, Yong Cao, Kaiqiang Sun, Jiangang Shi, Yuan Wang

“…Through integrative analysis of single-cell RNA-seq data from intervertebral discs (IVDs), we have firstly uncovered that the aberrant accumulation of R-Loops—a type of triple-stranded nucleic acid structure—can result in the cytoplasmic accumulation of double-stranded DNA (dsDNA) and activate cGAS/STING signaling and induce cellular senescence in nucleus pulposus cells (NPCs) during IVDD. …”
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Cold storage of human precision-cut lung slices in TiProtec preserves cellular composition and transcriptional responses and enables on-demand mechanistic studies by M. Camila Melo-Narvaez, Fee Gölitz, Eshita Jain, Janine Gote-Schniering, Mircea Gabriel Stoleriu, Wilhelm Bertrams, Bernd Schmeck, Ali Önder Yildirim, Ursula Rauen, Timo Wille, Mareike Lehmann

“…Viability, metabolic activity, and tissue structure were determined. Moreover, bulk-RNA sequencing was used to study transcriptional changes, regulated signaling pathways, and cellular composition after cold storage. …”
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Ephaptic conduction in tonic–clonic seizures by Avinoam Rabinovitch, Revital Rabinovitch, Ella Smolik, Yaacov Biton, Doron Braunstein

“…ObjectivesElectroencephalograms (EEGs) or multi-unit activities (MUAs) of tonic–clonic seizures typically exhibit a distinct structure. After a preliminary phase (DC shift, spikes), the tonic phase is characterized by synchronized activity of numerous neurons, followed by the clonic phase, marked by a periodic sequence of spikes. …”
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Mathematical Analysis Of A Modular Network Coordinating The Cell Cycle And Apoptosis by Gheorghe Craciun, Baltazar Aguda, Avner Friedman

“…Recent work of Aguda and Algar suggests a modular organization of regulatory molecular pathways linking the cellular processes of division and apoptosis. We carry out a detailed mathematical analysis of the Aguda-Algar model to unravel the dynamics implicit in the model structure. …”
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Clinical-laboratory and instrument indices of the thyroid gland state after surgical treatment of tumors of the chiasmatic-cellar region by Ya. A. Kan, M. G. Zhestikova, S. M. Bryzgalina, N. P. Shakhvorost

“…Most patients, who had been operated in terms of tumours of chiasmal-cellular area, have normal volume and structure of thyroid gland in the background of decreased level of free thyroxine and absence of increasing of level of TSH on the principle of feedback, it indicates to the secondary character of destruction of thyroid gland. …”
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