Biocompatibility and drug release kinetics of TiNbZrSn femtosecond laser-induced superhydrophilic structures by Tahir Nawaz, Vinod Paul, Sidrah Younus, Shahbaz Ahmad, Mehmet Egilmez, Wael Abuzaid, Ganjaboy Boltaev, Noor Akbar, Mustafa Khamis, Ghaleb A. Husseini, Ali S. Alnaser

“…Metal-based orthopedic implants have been subjected to various fabrication and treatment methods to enhance their biological activities at the host site. Modifying the structure, improving the hydrophilicity, and developing controlled-release drug delivery systems can improve cellular adhesion, proliferation, osseointegration, and differentiation. …”
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Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. by Robert A Dick, Chaoyi Xu, Dustin R Morado, Vladyslav Kravchuk, Clifton L Ricana, Terri D Lyddon, Arianna M Broad, J Ryan Feathers, Marc C Johnson, Volker M Vogt, Juan R Perilla, John A G Briggs, Florian K M Schur

“…Retrovirus assembly is driven by the multidomain structural protein Gag. Interactions between the capsid domains (CA) of Gag result in Gag multimerization, leading to an immature virus particle that is formed by a protein lattice based on dimeric, trimeric, and hexameric protein contacts. …”
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West Nile virus - a re-emerging global threat: recent advances in vaccines and drug discovery by Deren Zehra Kocabiyik, Lizdany Flórez Álvarez, Lizdany Flórez Álvarez, Edison Luiz Durigon, Edison Luiz Durigon, Carsten Wrenger, Carsten Wrenger

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Cellular events and biomarkers of wound healing by Shah Jumaat Mohd. Yussof, Effat Omar, Dinker R. Pai, Suneet Sood

“…Researchers have identified several of the cellular events associated with wound healing. Platelets, neutrophils, macrophages, and fibroblasts primarily contribute to the process. …”
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Structural remodeling activates bacterial anti-phage immunity: insights from HerA-DUF4297 by Xiaoyan Wang, Xiaoyan Wang, Leiliang Zhang, Leiliang Zhang

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On the Spatial Boundedness of Cellular RDA-nets by Vladimir A. Bashkin

“…This formalism is a hybrid of Petri nets and asynchronous Cellular Automata and is designed for modeling multi-agent systems with dynamic spatial structure. …”
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Research on computationally generative design of woven braced structure based on fiber composite material in architectural design industry by Peiqi Xu, Yiming Liu, Yafan Zhang, Nianxiong Liu

“…Moreover, based on the ant colony algorithm and the algorithm principle of cellular automata on the Java platform, the study designs a generative system with iterative computing of force as the major axis to achieve the self-organization and adaptability of the braced structure. …”
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Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses by Abhishek Cukkemane, Nina Becker, Tatsiana Kupreichyk, Henrike Heise, Dieter Willbold, Oliver H. Weiergräber

“…DISC1 associates with over 300 proteins and is associated with several physiological roles ranging from mitosis to cellular differentiation. Yet, the structural features of the protein are poorly characterized. …”
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Cysteine-rich intestinal protein family: structural overview, functional diversity, and roles in human disease by Xilin Ye, Qianben Song, Lumiao Zhang, Mengjia Jing, Yu Fu, Wei Yan

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Enduring memory consequences of early-life stress / adversity: Structural, synaptic, molecular and epigenetic mechanisms by Tallie Z. Baram, Matthew T. Birnie

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Structural insights into triglyceride storage mediated by fat storage-inducing transmembrane (FIT) protein 2. by David A Gross, Erik L Snapp, David L Silver

“…FIT proteins do not share primary sequence homology with known proteins and no structural information is available to inform on the mechanism by which FIT proteins function. …”
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Structural and mechanistic diversity in p53-mediated regulation of organismal longevity across taxonomical orders. by Romani Osbourne, Kelly M Thayer

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Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis. by Marcos V A S Navarro, Peter D Newell, Petya V Krasteva, Debashree Chatterjee, Dean R Madden, George A O'Toole, Holger Sondermann

“…Here, we elucidate the molecular mechanism of autoinhibition and activation of LapD based on structure-function analyses and crystal structures of the entire periplasmic domain and the intracellular signaling unit in two different states. …”
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Structural insight into the cGAS active site explains differences between therapeutically relevant species by Alexander M. Skeldon, Li Wang, Nicolas Sgarioto, Ramsay E. Beveridge, Silas Chan, Stephane Dorich, Valerie Dumais, Nadine Fradet, Samuel Gaudreault, Philippe LeGros, Daniel McKay, Ria Seliniotakis, Daniel V. Sietsema, Lingling Zhang, Marc-Olivier Boily, Jason D. Burch, Alex Caron, Lee D. Fader, Lodoe Lama, Wei Xie, Dinshaw J. Patel, Thomas Tuschl, Michael A. Crackower, Kelly A. Pike

“…A single threonine to isoleucine substitution between human and mouse cGAS drives compound activity, as demonstrated by biochemical, cellular, and in vivo studies. Finally, we utilize a structurally enabled design approach to engineer a novel chemical inhibitor with excellent potency for both human and mouse enzymes by targeting key interactions within the enzyme active site. …”
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Ameliorative Hypoglycemic Effect of 1-DNJ via Structural Derivatization Followed by Assembly Into Selenized Nanovesicles by Ruan S, Du Y, Zhang X, Zhang X, Kang H

“…Furthermore, N-1-DNJ-Se@NVs demonstrated long-lasting hypoglycemic effect and increased cellular uptake efficiency.Conclusion: Our findings suggest that structural derivatization improves the oral delivery of 1-DNJ and prolongs its therapeutic effect via selenized nanovesicles, positioning N-1-DNJ-Se@NVs as a promising nanomedicine for diabetes management.Keywords: 1-deoxynojirimycin, nanovesicles, selenium, sustained release, hypoglycemic effect, bioavailability…”
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Advances in the study of Ophiopogon japonicus polysaccharides: structural characterization, bioactivity and gut microbiota modulation regulation by Jiani Li, Jiani Li, Jiani Li, LiQuan Zhou, LiQuan Zhou, LiQuan Zhou, ZuoWei Xiao, ZuoWei Xiao, ZuoWei Xiao

“…Emerging evidence indicates that OJPS modulates the composition and structural organization of the gut microbiota, thereby maintaining intestinal barrier integrity and enhancing both gastrointestinal and systemic homeostasis. …”
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Parameters Derived from Integrated Nuclear Fluorescence, Syntactic Structure Analysis, and Vascularization in Human Lung Carcinomas by Klaus Kayser, Barbara Richter, Richard Stryciak, Hans‐Joachim Gabius

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Structural and functional insights of ZnT1 C-terminal domain as a regulator of zinc transport by Tomer Eli Ben Yosef, Itamar Kass, Anat Shahar, Ekaterina Eremenko, Alon Monsonego, Daniel Gitler, Arie Moran, Raz Zarivach

“…Abstract Zinc is an essential trace element vital for cellular function, and its homeostasis is tightly regulated. …”
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Structural and functional analysis of the accessory gene regulators of Staphylococcus aureus and Staphylococcus epidermidis: an in Silico approach by Subhamoy Dey, Tuhin Manna, Kartik Chandra Guchhait, Monalisha Karmakar, Debarati Jana, Priyanka Raul, Saroj Ballav, Mousumi Manna, Subrata Hazra, Amiya Kumar Panda, Chandradipa Ghosh

“…Artificial intelligence and machine learning based AlphaFold and TrRosetta were used to determine the tertiary structures of the proteins. Structure-based ab initio models could forecast subcellular localization, domain length, molecular docking, and simulation of Agrs in the isolates belonging to Staphylococcus sp. …”
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Structural and Functional Differences in the Bacterial Community of Chernozem Soil Under Conventional and Organic Farming Conditions by Darya V. Poshvina, Alexander S. Balkin, Anastasia V. Teslya, Diana S. Dilbaryan, Artyom A. Stepanov, Sergey V. Kravchenko, Alexey S. Vasilchenko

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