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The NONO protein regulates nonclassical DNA structure: Effects on circadian genes and DNA damage
Published 2025-05-01“…We postulated a regulatory role of Nono on R-loops, the class of non-B DNA structures that form during transcription. We confirmed this by showing a broad effect of Nono on genome-wide R-loop homeostasis. …”
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Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins.
Published 2015-09-01“…The structural constraint of membrane proteins may exemplify convergent evolution of cellular motors across species. …”
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Effect of ZnO NPs on Ovarian Histological Structure and Function in Adult Female Rats
Published 2024-10-01“…The aim of this study was to find out the effect of ZnO NPs on the histological structure and functions of the ovary, as well as to determine the levels of gonadotropin hormones (FSH and LH). …”
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Age-dependent glial heterogeneity and traumatic injury responses in a vertebrate brain structure
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Integrating Sequence- and Structure-Based Similarity Metrics for the Demarcation of Multiple Viral Taxonomic Levels
Published 2025-04-01“…Viruses exhibit significantly greater diversity than cellular organisms, posing a complex challenge to their taxonomic classification. …”
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Structure-Based Function of Humic Acid in Abiotic Stress Alleviation in Plants: A Review
Published 2025-06-01“…This review highlights the structural characteristics of HA, its structure-based functions, and the mechanisms involved in plant stress alleviation. …”
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Progress in Structure and Function of GP5 Protein of Porcine Reproductive and Respiratory Syndrome Virus
Published 2023-02-01“…GP5 protein contains multiple epitopes, which can interact with cellular receptors thus affect viral infection and replication. …”
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Mechanical Design of a Novel Functionally Graded Lattice Structure for Long Bone Scaffolds
Published 2025-05-01“…Open-cellular Ti6Al4V lattice structures have found application in porous scaffolds that can match the properties of human bone, which consists of a dense cortical shell and a less-dense cancellous core with an apparent density ranging from 1.3 to 2.1 g/cm<sup>3</sup> and 0.1 to 1.3 g/cm<sup>3</sup>, respectively. …”
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Hippocampal structure, patterns of the calcium-binding proteins and neuron numbers in small echolocating bats
Published 2025-08-01“…Neuroanatomical and ecological variability and unique traits within echolocating bats as shown here can provide a rich source for investigating structure-function relationships.…”
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The Impact of Polycomb Group Proteins on 3D Chromatin Structure and Environmental Stresses in Plants
Published 2025-03-01“…Polycomb Group (PcG) proteins and their catalytic activity play an indispensable role in transcriptional regulation, developmental processes, and the maintenance of cellular identity. In plants, PRC1 and PRC2 deposit H2Aub and H3K27me3, respectively, and also play an important role in influencing three-dimensional (3D) chromatin structure. …”
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Polyphosphate kinase regulates LPS structure and polymyxin resistance during starvation in E. coli.
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Altered extracellular matrix structure and elevated stiffness in a brain organoid model for disease
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Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation
Published 2025-01-01“…Structure-guided mutagenesis confirms the role of critical amino acid residues required for filament formation, oligomerization and disassembly of mTORC1 protein complex. …”
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Mapping the Intellectual Structure of COVID-19 Scientific Articles in Iran: A Scientometrics Study
Published 2025-04-01“…These clusters include: COVID-19 and mental health pressures (anxiety, stress, and depression); the mental health and quality of life of nurses and healthcare workers; the role of health monitoring and physical activities in preventing the COVID-19 epidemic (including the impact of electronic services); the effect of mesenchymal stem cells on immune system modulation in COVID-19 (immune regulation and cellular responses); respiratory infectious diseases; diagnostic tests for COVID-19 and antiviral treatments; the application of nanoparticles in the production of the coronavirus vaccine; examination of the molecular structure of the coronavirus through molecular dynamics simulations; coronavirus detection using artificial intelligence; specialized care for the elderly with chronic diseases; kidney disorders in COVID-19 patients; prevention of acute respiratory infectious diseases in vulnerable populations; and the effects of COVID-19 on the central nervous system. …”
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PcG-mediated higher-order chromatin structures modulate replication programs at the Drosophila BX-C.
Published 2013-01-01“…Using Drosophila embryonic cell lines, we find that, while presence of specific PcG complexes and underlying transcription state are not the sole determinants of cellular replication timing, PcG-mediated higher-order structures appear to dictate the timing of replication and maintenance of the silenced state. …”
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