Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis by Jeong Seon Kim, Zhenhang Chen, Sara Andrea Espinosa Garcia, Christoph Buhlheller, Botao Zhang, Stephen J. Richards, Tingfei Chen, Jingjing Wu, Ronald C. Bruntz, Marisa E. Gilliam, Mitsuo Yamauchi, Bo Liang, Houfu Guo

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Structural insights into polymerase-catalyzed FAD capping of hepatitis C virus RNA by De-Ping Wang, Rong Zhao, Wen-Shu Hu, Hai-Ning Li, Ji-Min Cao, Xin Zhou, Ye Xiang

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Structural and molecular distinctions of primary and secondary spines in the sea urchin Lytechinus variegatus by Elise Hebert, Madison Silvia, Gary M. Wessel

“…We hypothesize that the secondary spines of the tropical variegated urchin species, Lytechinus variegatus, are morphologically and molecularly distinct structures from primary spines and not just small versions of the large spines. …”
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Structural analysis of viral ExoN domains reveals polyphyletic hijacking events. by Adrián Cruz-González, Israel Muñoz-Velasco, Wolfgang Cottom-Salas, Arturo Becerra, José A Campillo-Balderas, Ricardo Hernández-Morales, Alberto Vázquez-Salazar, Rodrigo Jácome, Antonio Lazcano

“…The proofreading activity of the ExoN domain has played a key role in the growth of nidoviral genomes, while in arenaviruses this domain partakes in the suppression of the host innate immune signaling. Sequence and structural homology analyses suggest that these proteins have been hijacked from cellular hosts many times. …”
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Structural features of synthetic glycoconjugates and efficiency of their interaction with glycoprotein receptors on the surface of hepatocytes by A. S. Nosova, Yu. A. Budanova, Yu. L. Sebyakin

“…This review contains the chemical structures of carbohydrate-based ligands.Conclusions. …”
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Structural insights into tRNA recognition of the human FTSJ1-THADA complex by Kensuke Ishiguro, Atsushi Fujimura, Mikako Shirouzu

“…Although the structure of the FTSJ1-WDR6 complex in yeast has been solved, the structural details of the FTSJ1-THADA complex formation and substrate recognition remain unclear. …”
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Peculiarity of structural and microstructural changes in the thymus in «catabolic» phase after experimental hyperthermia by S. V. Michurina, D. V. Vasendin, I. Yu Ischenko

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Oversized nanodiscs for combined structural and functional investigation of multicomponent membrane protein systems by Bozhidar S. Ivanov, Judy Hirst

“…Abstract Membrane proteins are fundamental to many crucial cellular processes but removing them from their native environment for structural and functional studies creates experimental challenges. …”
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Antibacterial, Structural and Optical Characterization of Mechano-Chemically Prepared ZnO Nanoparticles. by Umair Manzoor, Sumera Siddique, Rafay Ahmed, Zobia Noreen, Habib Bokhari, Iftikhar Ahmad

“…Structural investigations, optical properties and antibacterial performance of the pure Zinc Oxide (ZnO) nanoparticles (NPs) synthesized by mechano-chemical method are presented. …”
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Retinoid X receptor heterodimers in hepatic function: structural insights and therapeutic potential by Renjie Xu, Linyue Zhang, Hao Pan, Yong Zhang

“…Retinoid X receptor (RXR) is a special member of the NRs, which not only responds to cellular signaling independently, but also regulates multiple signaling pathways by forming heterodimers with various other NR. …”
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Structural and functional state of blood lymphocytes in patients with infectious mononucleosis with different course by Ya. V. Kolesnyk, T. O. Briukhanova, M. Yu. Sliepchenko, O. A. Nakonechna, O. H. Sorokina

“…The aim was to determine the structural and functional status of blood lymphocytes in patients with acute and prolonged course of infectious mononucleosis (IM) in children. …”
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Dissecting non-B DNA structural motifs in untranslated regions of eukaryotic genomes by Aruna Sesha Chandrika Gummadi, Divya Kumari Muppa, Venakata Rajesh Yella

“…In functional areas of genomes, non-B DNA structures such as cruciform, curved, triplex, G-quadruplex, and Z-DNA structures are common and have an impact on cellular physiology. …”
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Genomic structural equation modeling elucidates the shared genetic architecture of allergic disorders by Jingsheng Ruan, Xinglin Yi

“…Methods Our study employed genomic structural equation modeling (Genomic SEM) to define the common factor representing the shared genetic architecture of allergic disorders. …”
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Caspases: structural and molecular mechanisms and functions in cell death, innate immunity, and disease by Eswar Kumar Nadendla, Rebecca E. Tweedell, Gary Kasof, Thirumala-Devi Kanneganti

“…Additionally, we highlight the emerging roles of caspases in cellular homeostasis and therapeutic targeting. Given the clinical relevance of caspases across multiple diseases, improved understanding of these proteins and their structure–function relationships is critical for developing effective treatment strategies.…”
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Structural basis for the activation of proteinase-activated receptors PAR1 and PAR2 by Zongyang Lyu, Xiaoxuan Lyu, Andrey G. Malyutin, Guliang Xia, Daniel Carney, Vinicius M. Alves, Matthew Falk, Nidhi Arora, Hua Zou, Aaron P. McGrath, Yanyong Kang

“…This triggers complex intracellular signaling via G proteins and beta-arrestins, linking external protease signals to cellular functions. To date, direct structural visualization of these ligand-receptor complexes has been limited. …”
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Developmental riboflavin deficiency results in structural and functional changes in the neural retina and RPE by Xue Zhao, Mustafa S. Makia, Muna I. Naash, Muayyad R. Al-Ubaidi

“…Riboflavin supplementation partially ameliorated these phenotypes by restoring retinal flavin and RTBDN levels, resulting in improvements in retinal structure and function. However, some cellular changes in the RPE remained irreversible and cone count was not restored. …”
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Structural basis of response regulator inhibition by a bacterial anti-activator protein. by Melinda D Baker, Matthew B Neiditch

“…This comparison reveals that RapF and RapH have strikingly similar overall structures, and that they have evolved different, non-overlapping surfaces to interact with diverse cellular targets. …”
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Structural Defects Associated with Craniectomy Induce Neuroinflammation and Blood–Brain Barrier Permeability by Aria W. Tarudji, Brandon Z. McDonald, Evan Curtis, Connor Gee, Forrest M. Kievit

“…While craniectomies are commonly used in TBI research, inadvertent dura disruption can result in structural deficits, impacting cellular function and neurobehavioral outcomes. …”
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Harnessing polydiacetylene (PDA): A review of structural mechanics and infectious disease detection by Soumendu Patra, Harshita Shand, Sayan Ghosal, Suvankar Ghorai

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Structural mechanism of CB1R binding to peripheral and biased inverse agonists by Punita Kumari, Szabolcs Dvorácskó, Michael D. Enos, Karthik Ramesh, Darrix Lim, Sergio A. Hassan, George Kunos, Resat Cinar, Malliga R. Iyer, Daniel M. Rosenbaum

“…To understand the mechanism of binding and inhibition of CB1R by peripherally restricted antagonists, we developed a nanobody/fusion protein strategy for high-resolution cryo-EM structure determination of the GPCR inactive state, and used this method to determine structures of CB1R bound to either MRI-1867 or MRI-1891. …”
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