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2221
Chiral materials in cancer therapy: Insight into metabolic, apoptotic, and immune pathways
Published 2025-02-01“…These nanomaterials demonstrate superior biocompatibility, minimal cytotoxicity, and enhanced cellular penetration. Furthermore, the tunability of their surface structures enables precise chirality control, fostering the development of advanced biomaterials capable of targeting tumor metabolism, inducing apoptosis, and modulating immune responses. …”
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2222
Nanomaterials as tools in plant transformation: A protoplast-centric perspective
Published 2024-11-01“…These NMs include organic, inorganic, and composite materials with many different structures, including nanofibers, nanoparticles (NPs), and nanomembranes. …”
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2223
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data
Published 2025-02-01“…Abstract Many studies have used single-cell RNA sequencing (scRNA-seq) to infer gene regulatory networks (GRNs), which are crucial for understanding complex cellular regulation. However, the inherent noise and sparsity of scRNA-seq data present significant challenges to accurate GRN inference. …”
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2224
Intracellular pathogen effector reprograms host gene expression by inhibiting mRNA decay
Published 2025-07-01“…Abstract Legionella pneumophila, an intracellular bacterial pathogen, injects effector proteins into host cells to manipulate cellular processes and promote its survival and proliferation. …”
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2225
Design low elastic modulus Ti–Zr–Nb-Hf-Cu multi-principal element alloys for dental application
Published 2025-07-01“…Incorporating copper into MPEAs with BCC structures presents a promising avenue for developing advanced dental implant materials.…”
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2226
Mechanisms and roles of membrane-anchored ATG8s
Published 2025-01-01“…These advancements hold therapeutic promise for treating autophagy-related diseases, including cancer and neurodegenerative disorders, by targeting ATG8-driven pathways that maintain cellular homeostasis.…”
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2227
Enlarged PML-nuclear bodies trigger conflicting cell cycle signal-mediated cytotoxicity in leukemia cells
Published 2025-08-01“…Here, we explored the link between cell cycle dynamics and the formation of PML-nuclear bodies (PML-NBs), intranuclear structures known to mediate cellular stress responses. …”
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2228
DNA vaccines as promising immuno-therapeutics against cancer: a new insight
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2229
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2230
Porphyromonas Gingivalis Virulence Factors and their Role in Undermining Antimicrobial Defenses and Host Cell Death Programs in the Pathobiology of Chronic Periodontal Disease
Published 2025-05-01“…In susceptible individuals, the disease is driven by dysbiotic microbiota on the tooth surface below the gum line, progressively eroding the tooth--supporting structures of the periodontium, including the alveolar bone. …”
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2231
Super-resolution upgrade for deep tissue imaging featuring simple implementation
Published 2025-06-01“…By combining two-photon excitation with patterned line-scanning and subsequent image reconstruction, we achieve imaging of sub-cellular structures in Pinus radiata, mouse heart muscle and zebrafish. …”
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2232
Chitosan Mediates Germling Adhesion in Magnaporthe oryzae and Is Required for Surface Sensing and Germling Morphogenesis.
Published 2016-06-01“…The fungal cell wall not only plays a critical role in maintaining cellular integrity, but also forms the interface between fungi and their environment. …”
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2233
miR-204 targeting of Ankrd13A controls both mesenchymal neural crest and lens cell migration.
Published 2013-01-01“…Focal adhesions are stringently regulated transient structures implicated in cell adhesion, spreading and motility during tissue development. …”
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2234
Hsp70 Isoforms Are Essential for the Formation of Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Compartments.
Published 2015-11-01“…Like other herpesviruses, multiple processes required for KSHV lytic replication, including viral transcription, viral DNA synthesis and capsid assembly occur in virus-induced intranuclear structures, termed replication and transcription compartments (RTCs). …”
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2235
R-loops: a key driver of inflammatory responses in cancer
Published 2025-07-01“…Abstract R-loops, which are noncanonical three-stranded nucleic acid structures formed when RNA hybridizes with complementary DNA strand while displacing the other DNA strand, have emerged as crucial players in cellular homeostasis and cancer pathogenesis. …”
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2236
Challenges of Scientific Research in Molecular Biotechnology in Yemen
Published 2023-02-01“…Biotechnology includes the application both of older biological knowledge, which is based on structures, functioning, and development of animals and plants in their ecological setting, and of newer approaches, which are based on an understanding of genetics and on the cellular and subcellular processes. …”
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2237
Evaluation of the use of reactive oxygen species (ROS) generated through oxyion® technology in strawberry (Fragaria × ananassa (Duchesne ex Weston) Duchesne ex Rozier cv. Monterrey...
Published 2018-04-01“…In most cases the presence of these chemical species is undesirable due to the impact they have on tissues and cellular structures, however, their effects can be used to control the incidence of microorganisms responsible for deterioration processes in fruits and vegetables. …”
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2238
Pushing Optical Resolution to the Few-Nanometer Scale via dSTORM Imaging of Expanded Specimen–Gel Composites
Published 2025-06-01“…Direct stochastic optical reconstruction microscopy (dSTORM) circumvents the diffraction limit of light, emerging as a powerful superresolution technique for visualizing subcellular structures with a nanoscale resolution of 10–20 nm. …”
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2239
Chromosome Instability and Micronucleus Frequency on the Oral Mucosa of HIV-positive Patients
Published 2025-05-01“… Abstract—Extranuclear structures known as micronuclei (MN) are composed of whole or fragmented chromosomes that were not incorporated into the nucleus following cell division. …”
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2240
Cardiovascular Diseases, Vital Organ Fibrosis, and Chronic Inflammation Associated with High-Intensity and/or High-Volume Exercise Training: Double-Edged Sword Effects of Vigorous...
Published 2025-01-01“…In conclusion, high-intensity training (HIT) and/or high-volume training (HVT) should not be recommended for middle-age and elderly people who have had cancer therapies or not in order to avoid an exacerbation of the consequences of aging or long-term cancer treatment effects on vital organ structures and functions.…”
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