Polarization-driven dynamic laser speckle analysis for brain neoplasms differentiation by Vahid Abbasian, Vahideh Farzam Rad, Parisa Shamshiripour, Davoud Ahmadvand, Arash Darafsheh

“…Label-free diagnostic methods, including intraoperative probes and cellular origin analysis techniques, hold promise for improving diagnostic accuracy. …”
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Advancements in Antioxidant-Based Therapeutics for Spinal Cord Injury: A Critical Review of Strategies and Combination Approaches by Yang-Jin Shen, Yin-Cheng Huang, Yi-Chuan Cheng

“…Spinal cord injury (SCI) initiates a cascade of secondary damage driven by oxidative stress, characterized by the excessive production of reactive oxygen species and other reactive molecules, which exacerbate cellular and tissue damage through the activation of deleterious signaling pathways. …”
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Parvoviruses NS1 oncolytic attributes: mechanistic insights and synergistic anti-tumor therapeutic strategies by Abdul Haseeb, Wafa Yousaf, Zhigang Cao, Kuohai Fan, Kuohai Fan, Na Sun, Panpan Sun, Yaogui Sun, Huizhen Yang, Wei Yin, Hua Zhang, Zhenbiao Zhang, Jia Zhong, Jianzhong Wang, Hongquan Li

“…Parvovirus is comprised of a single-stranded DNA structure, encompassing distinct structural and non-structural proteins. …”
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Zebrafish as a model for human epithelial pathology by Ahmed Abu-Siniyeh, Moayad Khataibeh, Walid Al-Zyoud, Majed Al Holi

“…This review explores the structural and functional homology between zebrafish and human epithelial tissues in organs, such as the gastrointestinal system, liver, and kidneys. …”
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hu.MAP 2.0: integration of over 15,000 proteomic experiments builds a global compendium of human multiprotein assemblies by Kevin Drew, John B Wallingford, Edward M Marcotte

“…Characterizing their composition is, therefore, required for our understanding of cellular functions. Unfortunately, we lack knowledge of the comprehensive set of identities of protein complexes in human cells. …”
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The stability and robustness of metabolic states: identifying stabilizing sites in metabolic networks by Sergio Grimbs, Joachim Selbig, Sascha Bulik, Hermann‐Georg Holzhütter, Ralf Steuer

“…To explore the possible dynamic behavior of metabolic networks in cases of lacking or incomplete enzyme‐kinetic information, we present a computational approach based on structural kinetic modeling. We derive statistical measures for the relative impact of enzyme‐kinetic parameters on dynamic properties (such as local stability) and apply our approach to the metabolism of human erythrocytes. …”
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Calmodulinopathy in inherited arrhythmia syndromes by Wen-Chin Tsai, Peng-Sheng Chen, Michael Rubart

“…Here, we aim to give an overview of biochemical and structural characteristics of CaM and progress toward updating current known CaM mutations and associated clinical phenotypes. …”
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Protective effects of naringin against oxidative stress, inflammation, apoptosis, and DNA damage in rats with doxorubicin-induced hepatotoxicity by Pelin Durukan Azman, Serkan Yildirim, Emin Sengul, Mohamad Warda, Samet Tekin, Furkan Aykurt, Ali Cinar

“…Histopathological evaluation showed that DOX-induced structural liver alterations, such as cellular degeneration and necrosis, were notably attenuated by naringin treatment. …”
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The dynamic relationship of brain‐derived neurotrophic factor and oxytocin: Introducing the concept of neurosocial plasticity by Jamshid Faraji, Gerlinde A. S. Metz

“…Abstract The human brain functions as a highly integrated system. Interconnected cellular and molecular networks within this system process sensory information, cognitive functions, and motor responses. …”
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Advances in Cancer Therapy: A Comprehensive Review of CDK and EGFR Inhibitors by Mohammed Hawash

“…Protein kinases have essential responsibilities in controlling several cellular processes, and their abnormal regulation is strongly related to the development of cancer. …”
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Ewing Sarcoma Protein: A Key Player in Human Cancer by Maria Paola Paronetto

“…The first part of this review will describe the structural features of EWS and its multiple roles in the regulation of gene expression, which are exerted by coordinating different steps in the synthesis and processing of pre-mRNAs. …”
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Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction. by Laurence H Arnold, Harriet C T Groom, Simone Kunzelmann, David Schwefel, Sarah J Caswell, Paula Ordonez, Melanie C Mann, Sabrina Rueschenbaum, David C Goldstone, Simon Pennell, Steven A Howell, Jonathan P Stoye, Michelle Webb, Ian A Taylor, Kate N Bishop

“…Here, we present combined structural and virological data demonstrating that in addition to allosteric activation and triphosphohydrolase activity, restriction correlates with the capacity of SAMHD1 to form "long-lived" enzymatically competent tetramers. …”
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What’s in a name? How organelles of endosymbiotic origin can be distinguished from endosymbionts by Ansgar Gruber

“…Distinguishing between organelles and symbionts according to their sexual symbiont integration is independent of any particular mechanism or structural property of the endosymbiont/host system under investigation.…”
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SNX27-Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling. by Boris Simonetti, Qian Guo, Manuel Giménez-Andrés, Kai-En Chen, Edmund R R Moody, Ashley J Evans, Mintu Chandra, Chris M Danson, Tom A Williams, Brett M Collins, Peter J Cullen

“…Here, we combine biochemical, structural, and cellular analyses to establish the mechanistic basis through which SNX27-Retromer, a major endosomal cargo adaptor, couples to the membrane remodeling endosomal SNX-BAR sorting complex for promoting exit 1 (ESCPE-1). …”
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Effects of Malathion Organophosphate Exposure on Histology of Salivary Glands of 3rd Instar Larva and Brain of Adult Common Fruit Fly (Drosophila melanogaster) by B. Bindhani, S. K. Saha

“…Data obtained reveals that larval salivary glands suffered severe structural distortion, including destruction of epithelial cell layer. …”
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Motor neuron synapse and axon defects in a C. elegans alpha-tubulin mutant. by Renee Baran, Liliana Castelblanco, Garland Tang, Ian Shapiro, Alexandr Goncharov, Yishi Jin

“…Regulation of microtubule dynamics underlies many fundamental cellular mechanisms including cell division, cell motility, and transport. …”
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Molecular mechanism on autophagy associated cardiovascular dysfunction in Drosophila melanogaster by Wei Zhang, Rong Zhou, Xinjuan Lei, Mofei Wang, Qinchun Duan, Yuanlin Miao, Tingting Zhang, Xinjie Li, Zhang Zutong, Liyang Wang, Odell D. Jones, Mengmeng Xu, Joseph Bryant, Jianjie Ma, Yingli Liu, Xuehong Xu

“…As a highly conserved cellular process, autophagy has been the focus of extensive research due to its critical role in maintaining cellular homeostasis and its implications in cardiovascular pathogenesis. …”
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Parameter Screening in Microfluidics Based Hydrodynamic Single-Cell Trapping by B. Deng, X. F. Li, D. Y. Chen, L. D. You, J. B. Wang, J. Chen

“…Numerical simulations were used to model this cellular trapping structure, quantifying the effects of channel on/off status and trapping structure geometries on the cellular trapping efficiency. …”
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Mechanistic understanding of GABA and trehalose in modulating plant response to drought stress by Ambika Choudhary, Eugenie Nepovimova, Vishnu D. Rajput, Tabarak Malik, Monika Choudhary, Nidhi Bhardwaj, Lukas Peter, Sunil Puri, Neetika Kimta

“…It enhances photosynthetic efficiency, regulates reactive oxygen species (ROS), and stabilizes cellular structures. Similarly, trehalose, a non-reducing disaccharide, acts as a crucial osmolyte, protecting plants from dehydration by stabilizing proteins and membranes, decreasing oxidative damage, and enhancing metabolic efficiency. …”
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WDR2 regulates the orphan kinesin KIN-G to promote hook complex and Golgi biogenesis in Trypanosoma brucei by Qing Zhou, Huiqing Hu, Ziyin Li

“…ABSTRACT The flagellum in Trypanosoma brucei plays crucial roles in cell locomotion, cell morphogenesis, and cell division, and its inheritance depends on the faithful duplication of multiple flagellum-associated structures. One of such cytoskeletal structures is a hairpin-like structure termed the hook complex, composed of a fishhook-like structure and a centrin arm structure, whose cellular functions remain poorly understood. …”
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