Age-dependent integration of cortical progenitors transplanted at CSF-neurogenic niche interface by Gretchen Greene, Nikorn Pothayee, Jahandar Jahanipour, Hyesoo Jie, Jung-Hwa Tao-Cheng, Emily Petrus, Dragan Maric, Alan P. Koretsky

“…This work demonstrates the feasibility and utility of integrating new neural tissue structures at ectopic sites into adult brain circuits to study host-transplant interactions.…”
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Identification of HMOX-1-Targeting Natural Compounds in <i>Camellia nitidissima</i> Chi for NSCLC Therapy: Integrating Bioassay and In Silico Screening Approaches by Lingqiu Zhang, Fan Zhang, Haimei Liang, Xiangling Qin, Chunmei Liang, Manlu Zhong, Yuemi Mo, Jinling Xie, Xiaotao Hou, Jiagang Deng, Erwei Hao, Zhengcai Du

“…Furthermore, it induced typical ferroptosis-related structural damage in mitochondria, including shrinkage and a reduction in size, increased membrane density, and a reduction or even the disappearance of cristae structures. …”
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Application of Antifreeze Substances in Food Cryopreservation by Mengxia Wu, Qin Xu, Han Ding, Dumin Zhao, Ying Wang, Baocai Xu

“…However, frozen storage often leads to protein oxidation, degradation, and cellular structural damage, compromising food palatability. …”
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Phytochemical Characterization and Anti-Biofilm Activity of <i>Primula veris</i> L. Roots by Antoaneta Trendafilova, Desislava Raykova, Viktoria Ivanova, Miroslav Novakovic, Paraskev Nedialkov, Tsvetelina Paunova-Krasteva, Ralitsa Veleva, Tanya Topouzova-Hristova

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Antioxidant and Ultrastructural Alterations in Wheat During Drought-Induced Leaf Senescence by Turana Y. Isgandarova, Samira M. Rustamova, Durna R. Aliyeva, Fuad H. Rzayev, Eldar K. Gasimov, Irada M. Huseynova

“…Ultrastructural analysis revealed progressive damage to chloroplast membranes, thylakoid structures, and mesophyll cell walls under stress conditions, particularly in sensitive genotypes. …”
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Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO by Vidya Narayanaswami PhD, Kenneth Dahl PhD, Vadim Bernard-Gauthier PhD, Lee Josephson PhD, Paul Cumming PhD, Neil Vasdev PhD

“…We provide a brief overview of the cellular expression and function of these targets, noting their selectivity for astrocytes and/or microglia, and highlight the classes of PET radiotracers that have been investigated in early-stage preclinical or clinical research studies of neuroinflammation.…”
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Application of multi-targeted CAR-T cell therapy in B-cell acute lymphoblastic leukemia by CAO Jinjin, DU Juan, QU Shanna, ZHU Mingyu, WANG Yang, HU Han, LIU Binlei

“…Chimeric antigen receptor-modified T (CAR-T) cell therapy, as a new type of cellular immunotherapy, has shown good clinical efficacy in the treatment of malignant hematological tumors, especially B-cell acute lymphoblastic leukemia. …”
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Morphological changes of mucous membrane of maxillary sinus at odontogenic perforative sinusitis by O. D. Baydik, S. V. Logvinov, S. G. Zubarev, P. G. Sysolyatin, A. A. Gurin

“…Methods of light, electronic microscopy and immunohystochemistry lead research of structural changes of a mucous membrane maxillary sinus at 43 patients with odontogenic perforative sinusitis. …”
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Time course transcriptome changes in Shewanella algae in response to salt stress. by Xiuping Fu, Duochun Wang, Xiling Yin, Pengcheng Du, Biao Kan

“…Transcript changes in amino acid metabolism, carbohydrate metabolism, energy metabolism, membrane transport, regulatory functions, and cellular signaling were found to be important for the high salt response in S. algae. …”
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Loss of Ufsp1 does not cause major changes at the neuromuscular junction. by Cristofer Calvo, Coalesco Smith, Taejeong Song, Fabian Montecino-Morales, Sakthivel Sadayappan, Douglas P Millay, Minchul Kim

“…UFMylation is a Ubiquitin-like post-translational modification involved in myriad of cellular processes. Enzymes involved in this pathway, including ligases and UFM1-specific proteases, are essential for development and homeostasis. …”
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The role of laminins in cancer pathobiology: a comprehensive review by Elena Nonnast, Emilia Mira, Santos Mañes

“…Abstract Laminins (LMs) are a family of heterotrimeric glycoproteins that form the structural foundation of basement membranes (BM). By acting as molecular bridges between cells and the extracellular matrix (ECM) through integrins and other surface receptors, they regulate key cellular signals that influence cell behavior and tissue architecture. …”
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Ultrastructural and transcriptional changes during a giant virus infection of a green alga by Andrian P. Gajigan, Christopher R. Schvarcz, Cecilia Conaco, Kyle F. Edwards, Grieg F. Steward

“…In the later stages, host transcripts associated with basic cellular processes were relatively more common, while developmental genes became less so. …”
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Polymer-Based Mass Cytometry Reagents: Synthesis and Biomedical Applications by Yin-Feng Wang, Wenying Wu, Ya-Hui Ge

“…Mass cytometry has promoted the development of single-cell analysis by enabling the highly multiplexed detection of cellular markers using metal-tagged antibodies or cells. …”
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Moracin M derivative targeting PDE4 for the treatment of psoriasis by Liru Chen, Deyan Wu, Sen Wang, Lingyu Wu, Youyou Chen, Baoli Li, Haibin Luo, Jian Li, Wenwen Liu

“…Natural products typically exhibit safety profiles and structural novelty, which are particularly advantageous for drug discovery. …”
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Resuscitation dynamics reveal persister partitioning after antibiotic treatment by Xin Fang, Kyle R Allison

“…Consistently, we observed many persister progeny have structural defects and transcriptional responses indicative of cellular damage, for both β‐lactam and quinolone antibiotics. …”
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Integration of the transcriptome and glycome for identification of glycan cell signatures. by Sandra V Bennun, Kevin J Yarema, Michael J Betenbaugh, Frederick J Krambeck

“…The integration of multiple data sets represents an important application of systems biology for understanding complex cellular processes.…”
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Asymmetry in centrosome maturation revealed through AIR-1 dynamics in the early Caenorhabditis elegans embryo by Shayne M. Plourde, Natalia Kravtsova, Adriana T. Dawes

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Modeling the consequences of age-linked rDNA hypermethylation with dCas9-directed DNA methylation in human cells. by Yana Blokhina, Abigail Buchwalter

“…Ribosomal DNA (rDNA) genes encode the structural RNAs of the ribosome and are present in hundreds of copies in mammalian genomes. …”
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Druggable proteins of Alistipes reveal promising antimicrobial targets against chronic intestinal inflammation by Saman Sohail, Ayesha Wisal, Sobia Rana, Rao Muhammad Abid Khan, Asad Ullah, Farooq-Ahmad Khan, Muhammad Irfan, Muhammad Imran, Paulo V. S. D. Carvalho, Renato Rozental, Farzana Shaheen, Farzana Shaheen, Syed Shah Hassan, Syed Shah Hassan

“…The 3D structures of the selected targets (LpxA and KdsB) revealed good druggability scores. …”
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Kingdom-specific lipid unsaturation calibrates sequence evolution in membrane arm subunits of eukaryotic respiratory complexes by Pooja Gupta, Sristi Chakroborty, Arun K. Rathod, K. Ranjith Kumar, Shreya Bhat, Suparna Ghosh, Pallavi Rao T, Kameshwari Yele, Raman Bakthisaran, R. Nagaraj, Moutusi Manna, Swasti Raychaudhuri

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