New insights into tuberous sclerosis complex: from structure to pathogenesis by Chao-Sheng Chen, Christopher H. S. Aylett

“…This review provides an overview of recent progress in understanding the molecular structure and function of this key protein complex, its role in cellular processes, pathogenesis, and current and future therapeutic strategies.…”
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Study of changes in the surface structure of tungsten irradiated by helium plasma by Л.Г. Сулюбаева, Б.К. Рахадилов, Е. Найманқұмарұлы, М.Б. Баяндинова, Н. Мұқтанова, Н.Е. Бердимуратов

“…It was found that when the negative potential on the target is varied by –500V/–1000V/–1500V, the formation of dislocation with chaotic and cellular structure of tungsten with an average grain size of (1‒25) μm is observed; it was revealed that the total values of elastic and plastic components of deformation across the tungsten grain differ from each other by about 2.5 times. …”
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Structure of the turnover-ready state of an ancestral respiratory complex I by Bozhidar S. Ivanov, Hannah R. Bridges, Owen D. Jarman, Judy Hirst

“…Despite detailed structural information on complex I, its mechanism of catalysis remains elusive due to lack of accompanying functional data for comprehensive structure-function analyses. …”
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Intercellular network structure and regulatory motifs in the human hematopoietic system by Wenlian Qiao, Weijia Wang, Elisa Laurenti, Andrei L Turinsky, Shoshana J Wodak, Gary D Bader, John E Dick, Peter W Zandstra

“…Combining genomic and phenotypic data with high‐content experiments, we have built a directional cell–cell communication network between 12 cell types isolated from human umbilical cord blood. Network structure analysis revealed that ligand production is cell type dependent, whereas ligand binding is promiscuous. …”
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Influence of a strong beam on structure and properties of plasma coatings by S.A. Guchenko, E.N. Eremin, V.M. Yurov, V.Ch. Laurynas, S.S. Kasimov, O.N. Zavatskaya

“… The effect of electron irradiation on the structure and properties of plasma coatings is studied. …”
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Transcription factor TCF4: structure, function, and associated diseases by R. R. Savchenko, N. A. Skryabin

“…Our understanding of human genes - particularly their structure, functions, and regulatory mechanisms - is still limited. …”
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Late grafted kidney dysfunction: morphological structure, criteria for diagnosis by E. S. Stolyarevich, N. A. Tomilina

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Decoding PDI diversity: Insights into structure, domains, and functionality in sorghum by Carla F. López-Gómez, Marc T. Morris, Karen Massel, Millicent Smith, Peter Crisp, Gerhard Schenk, Ian D. Godwin

“…Proteins play indispensable roles in cellular function, acting as both structural components and catalysts for essential biological processes. …”
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Rediscovering the rete ovarii, a secreting auxiliary structure to the ovary by Dilara N Anbarci, Jennifer McKey, Daniel S Levic, Michel Bagnat, Blanche Capel

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From Structure to Function: The Promise of PAMAM Dendrimers in Biomedical Applications by Said Alamos-Musre, Daniel Beltrán-Chacana, Juan Moyano, Valeria Márquez-Miranda, Yorley Duarte, Sebastián Miranda-Rojas, Yusser Olguín, Juan A. Fuentes, Danilo González-Nilo, María Carolina Otero

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Refining the genetic structure and admixture history of Hmong-Mien populations by Meiqing Yang, Huangzhen Huang, Han Zhang, Wen Wan, Kongyang Zhu, Rui Wang, Jinxi Li, Lu Chen, Jiang Huang, Chuan-Chao Wang

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3D Printing parameter optimisation combined with heat treatment for achieving high density and enhanced performance in refractory high-entropy alloys by Deyu Jiang, Miao Luo, Changxi Liu, Yashuo Zhang, Lai-Chang Zhang, Kuaishe Wang, Wen Wang, Lechun Xie, Liqiang Wang, Weijie Lu, Di Zhang

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Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B by Xin‐Yan Fang, Cong Sun, Chu Xie, Bing‐Zhen Cheng, Zheng‐Zhou Lu, Ge‐Xin Zhao, Sen‐Fang Sui, Mu‐Sheng Zeng, Zheng Liu

“…Additionally, the structure of the non‐neutralizing monoclonal antibody 2C4 bound to KSHV gB domain IV is resolved. …”
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In-situ heating TEM observation of solidification cell evolutions in an Al-Fe alloy built by laser-powder bed fusion by Ji-Yun Wang, Verner Soh, Pei Wang, Tzu-Ching Tsao, Ming-Wen Chu, Ming-Hao Lee, Zhongji Sun, Shao-Pu Tsai

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Proportional Topology Optimization algorithm for two-scale concurrent design of lattice structures by Minh Ngoc Nguyen, Duy Vo, Tinh Quoc Bui

“… In this paper, the Proportional Topology Optimization (PTO) algorithm is extended for the two-scale concurrent topology optimization, in which both the structure and material cellular micro-structure are subject to design. …”
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Tertiary lymphoid structures in the microenvironment of colorectal cancer: exploring new therapeutic targets by Nan-Nan Dai, Man-Yi Hu, Jian-Ping Wang, Zhi-Hui Dai, Li Xu, Tai-Wei Ye

“…Abstract Immunotherapy has shown limited efficacy in colorectal cancer (CRC), necessitating the urgent identification of novel immunotherapeutic targets to address this challenge. Tertiary lymphoid structures (TLSs) are complex immune structures that spontaneously form within and outside of the tumor microenvironment, resembling secondary lymphoid organs. …”
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Unleashing virus structural biology: Probing protein and membrane intermediates in the dynamic process of membrane fusion by Kelly K. Lee

“…Additionally, the processes viruses carry out serve as excellent model systems for analogous cellular processes, but in more accessible form. Capturing and analyzing these dynamic events poses a major challenge for many structural biological approaches due to the size and complexity of the assemblies and the heterogeneity and transience of the functional states that are populated. …”
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Spatiotemporal regulation of alginate sub-structures at multiple scales revealed by monoclonal antibodies by Catherine T. Jones, Cassie Bakshani, Ieva Lelenaite, Jozef Mravec, Stjepan Krešimir Kračun, Jeff Pearson, Mathew D. Wilcox, Kevin Hardouin, Sonia Kridi, Cécile Hervé, William G.T. Willats

“…Using these probes, we obtained new insight into how structural features of alginates are regulated at different scales, from cellular to seasonal.…”
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Radiation drives tertiary lymphoid structures to reshape TME for synergized antitumour immunity by Shuling Li, Kuifei Chen, Zhenwei Sun, Meng Chen, Wenhu Pi, Suna Zhou, Haihua Yang

“…Moreover, B cells, macrophages and other immune cells may also be affected. Tertiary lymphoid structure (TLS) is a unique structure within the TME and a class of aggregates containing T cells, B cells and other immune cells. …”
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Elucidating Collapse-Resistant Mechanisms of Pore Geometries in Fire Ant Nest Cavities by Tyler Felgenhauer, Satchi Venkataraman, Ethan Mullen

“…These findings could inform the design of lightweight and durable cellular structures in various engineering fields.…”
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