Computer-guided identification of novel inhibitors of apoptosis-signaling kinase 1 from Spondia mombim bioactive compounds against colorectal cancer by Olusola Olalekan Elekofehinti, Hannah Oluwaseun Popoola, Adedotun Olayemi Oluwatuyi, Opeyemi Iwaloye, Moses Orimoloye Akinjiyan, Oluwamodupe Cecilia, Frank Abimbola Ogundolie, Olalekan Isaac Olatunde, Oussama Abchir, Samir Chtita, Joao Batista Texeira Rocha

“…These compounds showed modest indices for ADMET parameters. Molecular dynamic simulation validated ellagic acid and (-)-catechin with greater binding stability as leading compounds. …”
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Shock reaction model for impact energy release behavior of Al/PTFE reactive material by Bao-yue Guo, Ke-rong Ren, Xia-yin Ma, Gan Li, Cai-min Huang, Zhi-bin Li, Rong Chen

“…At the same time, the shock reaction model is embedded into the material library of the LS-DYNA nonlinear dynamic simulation software as a secondary development. …”
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The efficacy of neoadjuvant immunotherapy and lymphocyte subset predictors in locally advanced esophageal squamous cell carcinoma: A retrospective study by Ruotong Wang, Shaodi Wen, Xiaoyue Du, Jingwei Xia, Bowen Hu, Yihan Zhang, Guoren Zhou, Feng Jiang, Xiaomin Lu, Miaolin Zhu, Xinyu Xu, Bo Shen

“…Evaluating the differentiation status and dynamic changes of peripheral blood immune cells may provide valuable predictive insights into treatment efficacy and prognosis.…”
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Exercise-induced anxiety impairs local and systemic inflammatory response and glucose metabolism in C57BL/6J mice by I. Gálvez, M.C. Navarro, S. Torres-Piles, L. Martín-Cordero, M.D. Hinchado, E. Ortega

“…Exercise strongly modulates the immune system, inducing a plethora of dynamic responses involving the innate immune cell function and inflammatory processes that contribute to both potential health benefits and harmful side effects. …”
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Fecal microbiome change in patients with ulcerative colitis after fecal microbiota transplantation by A. Y. Tikunov, V. V. Morozov, A. N. Shvalov, A. V. Bardasheva, E. V. Shrayner, O. A. Maksimova, I. O. Voloshina, V. V. Morozova, V. V. Vlasov, N. V. Tikunova

“…Intestinal human microbiota is a dynamic system that is under the pressures of its host organism and external factors. …”
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Temporal trends and differences of SARS-CoV-2-specific antibody responses in symptomatic and asymptomatic subjects: a longitudinal study from Umbria in Italy by Iosief Abraha, Paolo Eusebi, Marta Micheli, Antonella Germani, Erica Pasquarelli, Sofia Pascolini, Rossana Antonietti, Sandro Argenti, Alessandra Fioravanti, Elisa Martini, Luana Aristei, Paola Mancinelli, Maria Letizia Ottaviani, Martina Roselli, Milena Barzacca, Erika Belardinelli

“…Objectives Dynamics of antibody responses following SARS-CoV-2 infection are controversial in terms of immunity and persistence. …”
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Association between atherogenic index of plasma and future risk of cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide pros... by Gaoshu Zheng, Jijie Jin, Fei Wang, Qianrong Zheng, Jiaxin Shao, Jiangnan Yao, Pan Huang, Hao Zhou, Jianghua Zhou

“…Conclusions Poor control level of AIP are associated with an increased risk of CVD events in the population of CKM stages 0–3. Long-term dynamic monitoring of changes in AIP may help in the early identification of patients at high risk of developing CVD in the individuals with CKM stages 0–3.…”
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System Design and Optimisation Study on a Novel CCHP System Integrated with a Hybrid Energy Storage System and an ORC by Jie Ji, Zujun Ding, Xin Xia, Yeqin Wang, Hui Huang, Chu Zhang, Tian Peng, Xiaolu Wang, Muhammad Shahzad Nazir, Yue Zhang, Baolian Liu, Xiaoying Jia, Ruisheng Li, Yaodong Wang

“…The design of the integrated system and the control strategy are displayed in detail. Several sets of dynamic energy demand profiles are selected to evaluate the performance of the integrated system. …”
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Taohong Siwu Decoction Exerts a Beneficial Effect on Cardiac Function by Possibly Improving the Microenvironment and Decreasing Mitochondrial Fission after Myocardial Infarction by Zhi-rong Luo, Han Li, Zhong-xin Xiao, Shui-jin Shao, Tian-tian Zhao, Yue Zhao, Fang-fang Mou, Bo Yu, Hai-dong Guo

“…The mitochondrial ROS production was measured using MitoSOX staining, and mitochondrial dynamics and mitophagy were evaluated with western blotting 7 days after THSWD treatment. …”
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Structure and metabolic function of spatiotemporal pit mud microbiome by Zhihua Li, Chi Zhao, Zhenyu Mao, Fengju Zhang, Ling Dong, Chuan Song, Yao Chen, Xin Fu, Zonghua Ao, Yanfei Xiong, Qin Hui, Weizhi Song, Petri Penttinen, Suyi Zhang

“…Horizontal gene transfer (HGT) was widespread in PM, particularly among clostridia, Bacteroidota, Bacilli, and Euryarchaeota, and was shown to play critical roles in fermentation dynamics, carbon fixation, methane production, and nitrogen and sulfur metabolism. …”
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A bibliometric analysis of the top 100 most cited articles on corticospinal tract regeneration from 2004 to 2024 by Saijilafu, Saijilafu, Ling-Chen Ye, Huanyi Li, Haokun Li, Xinyi Lin, Kehui Hu, Zekai Huang, Chimedragchaa Chimedtseren, Linjun Fang, Saijilahu, Ren-Jie Xu

“…Our findings unveiled the dynamics and trends within the field of CST regeneration, providing a scientific foundation for advancing clinical applications. …”
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Effects of 24-hour urine-output trajectories on the risk of acute kidney injury in critically ill patients with cirrhosis: a retrospective cohort analysis by Jia Wang, Dongdong Niu, Xiaolin Li, Yumei Zhao, Enlin Ye, Jiasheng Huang, Suru Yue, Xuefei Hou, Jiayuan Wu

“…More attention should be paid to the dynamic nature of urine-output changes over time, which may help guide early intervention and improve patients’ prognoses.…”
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Enhancing Quality Fruit Composition in Red Currant Cultivars by Foliar Calcium Application across Preharvest and Postharvest Stages by Olga Panfilova, Ibrahim Kahramanoğlu, Gabrijel Ondrasek, Nelli Ryago, Larisa Leonteva, Chunpeng (Craig) Wan, Mikhail Tsoy, Volkan Okatan, Olga Golyaeva, Olga Loretts, Viktor Kukhar, Mikhail Karpukhin

“…This study aimed to assess the impact of foliar application of Ca-organomineral (Ca-OM) suspension on total soluble solids (TSS) and Ca dynamics in leaves and berries across five red currant cultivars during the vegetation and storage. …”
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Arbovirus vectors of epidemiological concern in the Americas: A scoping review of entomological studies on Zika, dengue and chikungunya virus vectors. by Reilly Jones, Manisha A Kulkarni, Thomas M V Davidson, RADAM-LAC Research Team, Benoit Talbot

“…Interestingly, information on Zika virus vector species composition was abundant, but sparse on Zika virus transmission dynamics. Few studies examined natural infection rates of Zika virus, vertical transmission, or co-infection with other viruses. …”
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KMO-driven metabolic reconfiguration and its impact on immune cell infiltration in nasopharyngeal carcinoma: a new avenue for immunotherapy by Nijun Chen, Yuan Zong, Chen Yang, Lei Li, Yang Yi, Jiawen Zhao, Xiaoyu Zhao, Xianfei Xie, Xingmei Sun, Ning Li, Liting Jiang

“…Histological analysis, coupled with public transcriptomic database interrogation, was utilized to investigate mitochondrial dynamics and metabolism across different cell types. …”
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Fetal Hemoglobin as a Predictive Biomarker for Retinopathy of Prematurity: A Prospective Multicenter Cohort Study in Portugal by Mariza Fevereiro-Martins, Laura Aguiar, Ângela Inácio, Carlos Cardoso, Ana Carolina Santos, Carlos Marques-Neves, Hercília Guimarães, Rui Pinto, Manuel Bicho

“…Red blood cell (RBC) transfusions, commonly performed in neonatal intensive care units (NICUs), reduce fetal hemoglobin (HbF) fraction, altering oxygen dynamics and potentially contributing to ROP. We aimed to investigate the relationship between RBC transfusions, HbF percentage, and ROP, evaluating HbF as a potential predictive biomarker. …”
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Serum Alkaline Phosphatase in Free-Ranging Male Moose Alces alces (Linnaeus 1758) of Different Age Groups by Maria A. Perevozchikova, Igor A. Domsky, Yulia A. Berezina, Professor Zhitkov Russian Research Institute of Game Management and Fur Farming, Kirov, Russia, Alexandr V. Economov

“…The study also revealed a certain correlation between alkaline phosphatase activity and body weight. The dynamics of alkaline phosphatase activity in ontogenesis reflected homeostatic changes in the moose body. …”
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Are Electromyography Data a Fingerprint for Patients with Cerebral Palsy (CP)? by Mehrdad Davoudi, Firooz Salami, Robert Reisig, Dimitrios A. Patikas, Nicholas A. Beckmann, Katharina S. Gather, Sebastian I. Wolf

“…Using Repeated Measures ANOVA, we examined the norm-distance (ND) of the kinematics, kinetics, and EMG patterns, in addition to the Kerpape-Rennes EMG-based Gait Index (EDI), EMG Profile Score (EPS), and Walking Dynamic Motor Control Index (DMC) before and after surgery. …”
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Photosynthetic characteristics of Paris polyphylla var. chinensis in response to different light intensities and soil water contents by Yaling Zhang, Yaling Zhang, Rong Xu, Rong Xu, Rong Xu, Zhaozhao Wang, Juan Zhang, Xinghao Tang, Yu Chen, Xiao-Li Yan, Lu-Ping Qu, Lu-Ping Qu

“…It is imperative to study the photochemical processes of P. polyphylla in order to determine the optimal levels of shading and moisture management for its cultivation in artificial environments.MethodsIn this study, six shading levels (no shading, 30%, 50%, 70%, 80% and 90% shading) and three soil water contents (20%, 40% and 60% of the soil water saturation capacity) were established to determine the appropriate shade intensity and soil moisture content for the growth of P. polyphylla.ResultsThe results showed that only the low shade groups (no shade and 30% shade) showed irreversible damage to the daily photosynthetic dynamics of the plant over the course of a day. It is important to note that excessive light can damage not only the quantum yield for electron transport (φDo) and PSII light quantum yield (Fv/Fm), but also various physiological mechanisms that can lead to overall plant damage and a decline in organic matter. …”
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Synergistic Antifungal Activity of Terbinafine in Combination with Light-Activated Gelatin–Silver Nanoparticles Against <i>Candida albicans</i> Strains by Atif Ullah, Fawad Ali, Farman Ullah, Sajid Khan Sadozai, Saeed Ahmed Khan, Sajid Hussain, Abdulwahed Fahad Alrefaei, Sajid Ali

“…Silver nanoparticles were produced through a light-activated, gelatin-based method, resulting in particle sizes ranging from 56.8 nm to 66.2 nm, confirmed by dynamic light scattering and scanning electron microscopy. …”
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