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AN EXPERIMENTAL STUDY OF THE EFFECT OF RARE POLYMORPHISMS OF HUMAN HBB, HBD AND F9 PROMOTER TATA BOXES ON THE KINETICS OF INTERACTION WITH THE TATA-BINDING PROTEIN
Published 2018-03-01“…In the present work, we investigate the effect of rare not annotated single-nucleotide polymorphisms (SNPs) of TATA boxes of these genes with an unknown manifestation on the TATA-binding protein interaction. To study the kinetic characteristics of TBP/TATA complex formation in vitro, doublestranded oligodeoxynucleotides identical to the TATA-containing portions of the promoters of the HBB, HBD and F9 genes (“normal” and minor alleles) and recombinant human TBP were used. …”
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3064
What if writing rock history was also writing with “ifs”? Or how Lester Bangs liked playing a trick on his reader’s perception of time
Published 2013-12-01Subjects: Get full text
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Aerosol layer height (ALH) retrievals from oxygen absorption bands: intercomparison and validation among different satellite platforms, GEMS, EPIC, and TROPOMI
Published 2025-01-01“…The correlations improve under conditions of higher absorbing aerosols (UVAI <span class="inline-formula">≥</span> 3), as the signal in the oxygen absorption band (O<span class="inline-formula"><sub>2</sub></span>–O<span class="inline-formula"><sub>2</sub></span> used by GEMS) is enhanced. …”
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The Clinical Values of Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Blood and Thyroid Nodules
Published 2017-01-01“…The aim of this study was to determine both the serum and intranodular levels of IGF-1 and insulin-like growth factor binding protein-3 (IGFBP-3) in patients with nodular thyroid diseases. …”
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Very large haematoma following the nonoperative management of a blunt splenic injury in a patient with preexisting liver cirrhosis: a case report
Published 2022-03-01“…The spleen is the most commonly injured organ after blunt abdominal trauma. Nonoperative management (NOM) is the standard treatment for blunt splenic injuries in haemodynamically stable patients without peritonitis. …”
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Discovery of a heparan sulfate binding domain in monkeypox virus H3 as an anti-poxviral drug target combining AI and MD simulations
Published 2025-01-01“…Using AI-based structural prediction tools and molecular dynamics (MD) simulations, we identified a novel, positively charged α-helical domain in H3 that is essential for HS binding. This conserved domain, found across orthopoxviruses, was experimentally validated and shown to be critical for viral adhesion, making it an ideal target for antiviral drug development. …”
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İÇ GİRİŞİMCİLİĞİN YENİLİK VE EKİP YÖNETİMİ İLE İLİŞKİSİ ÜZERİNE BİR ARAŞTIRMA - THE RELATIONSHIP OF THE INTREPRENEURSHIP AND INNOVATION: A RESEARCH ON BANK EMPLOYEES
Published 2017-12-01“…Araştırmada bankacılık sektöründeçalışanların iç girişimciliğe verdiği önem düzeyini belirlemek yenilik ve ekipyönetimi ile olan olumlu ilişkisini ortaya koymak amaçlanmıştır. Bu bağlamdaBurdur ve Denizli ilinde bulunan kamu ve özel sektör banka şubelerinde anketçalışması yapılarak çalışanların iç girişimcilik, yenilik ve ekip çalışmasınaeğilimleri çeşitli faktörler açısından incelenmiş ve elde edilen bulgular SPSS15 istatistiksel veri analiz programında değerlendirilmiştir. …”
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Prevalence of metabolic syndrome and its risk factors among the government bank’s employees of district Bijnor, Uttar Pradesh: A cross-sectional study
Published 2024-12-01“…To find out the prevalence of MetS and various risk factors associated with it through MetS’s screening criteria. 2) To find out the health risk status and stress level among bank’s employees in the government sector. Material and Methods: A medical health camp was organised for all bank’s employees to rule out the various health-related disorders. …”
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Negative Association of Gulf War Illness Symptomatology with Predicted Binding Affinity of Anthrax Vaccine Antigen to Human Leukocyte (HLA) Class II Molecules
Published 2025-01-01“…Results: We found that the severity of GWI symptomatology was negatively and significantly correlated with the strength of the predicted binding affinity of PA peptides to HLA-II molecules (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>r</mi><mo>=</mo><mo>−</mo><mn>0.356</mn><mo>,</mo><mo> </mo><mi>p</mi><mo><</mo><mn>0.001</mn><mo>)</mo></mrow></semantics></math></inline-formula>; the stronger the overall binding affinity, the weaker the symptoms. …”
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NF-κB-Inducing Kinase Is Essential for Effective c-Rel Transactivation and Binding to the <i>Il12b</i> Promoter in Macrophages
Published 2025-01-01“…When looking more specifically at the regulation of the <i>Il12b</i> promoter, we found that c-Rel bound to the NF-kB consensus sequence in macrophages from WT mice 1 hr. after LPS challenge, whereas in <i>aly</i>/<i>aly</i> macrophages, the transcription factor bound to the promoter was p65. …”
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Interference analysis between IMT-2020 (5G) system and broadcasting satellite service system in the band of 24.65~25.25 GHz
Published 2018-07-01“…Based on the Agenda Item 1.13 of WRC-19 and requirements for domestic compatibility analysis of 5G candidate frequency bands above 6 GHz,the interference from IMT-2020 system (5G) to broadcasting satellite service system in 24.65~25.25 GHz band was studied.The Monte Carlo simulation method was used to assess the aggregate interference from IMT base station (BS) to the up-link of feeder link of broadcasting satellite where the geostationary orbit satellite at 59℃,85℃ and 113℃ longitude.The aggregate interference level from 5G system to the two kinds of carriers of the satellite system with different orbits was evaluated via simulation analysis.Research results show that the IMT-2020 (5G) system will not cause harmful interference for broadcasting satellite services system.The results can provide technology basis for future planning of IMT-2020 (5G) system in millimeter wave and protecting of broadcasting satellite system.…”
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The Anthelmintic Activity of <i>Nepeta racemosa</i> Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies
Published 2025-01-01“…MeOH extract, <i>n</i>-hexane, dichloromethane (DCM), ethyl acetate (EtOAc), <i>n</i>-buthanol (<i>n</i>-BuOH) and aqueous (H<sub>2</sub>O) subextracts, and quantify rosmarinic acid in the active extract by the HPLC method, and perform in silico molecular docking studies of rosmarinic acid to examine its binding interactions with tubulin. …”
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Effect of Narrow Band Ultraviolet B Therapy versus Methotrexate on Serum Levels of Interleukin-17 and Interleukin-23 in Egyptian Patients with Severe Psoriasis
Published 2013-01-01“…To compare the effect of narrow band ultraviolet B (NB-UVB) and methotrexate (MTX) therapy on serum levels of IL-17 and IL-23 in psoriatic patients. …”
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KRİZ ÖNCESİ VE KRİZ SONRASI DÖNEMLER İTİBARİYLE KATILIM BANKALARI VE TİCARİ BANKALARIN KARLILIĞI ÜZERİNE KARŞILAŞTIRMALI BİR ARAŞTIRMA
Published 2014-08-01Subjects: Get full text
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Conceptualizing digital finance as a precursor for financial inclusion and financial service usage in Uganda
Published 2025-12-01Subjects: Get full text
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