SARS-CoV-2 Evolution: Implications for Diagnosis, Treatment, Vaccine Effectiveness and Development by Fabrizio Angius, Silvia Puxeddu, Silvio Zaimi, Serena Canton, Sepehr Nematollahzadeh, Andrea Pibiri, Ilenia Delogu, Gualtiero Alvisi, Meng Ling Moi, Aldo Manzin

“…These mutations have significantly affected transmissibility, immune evasion, and vaccine efficacy, leading to multiple pandemic waves with over half a billion cases and seven million deaths globally. Despite several strategies, from rapid vaccine development and administration to the design and availability of antivirals, including monoclonal antibodies, already having been employed, the persistent circulation of the virus and the emergence of new variants continue to result in high case numbers and fatalities. …”
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Effect of Sports Energy Drink on Fat Metabolism and Weight Loss of College Students by Huan Chu, Wenyong Zhou, Shanshan Wang

“…At present, the total annual output of beverages in the world exceeds 300 billion liters, and functional beverages have become the fastest growing beverage varieties. …”
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Trends in novel antiandrogen receptor signal inhibitor use and medical costs in prostate cancer by Hikari Miura, Hayato Yamamoto, Yoshiharu Okuyama, Noritaka Ishi, Ryuma Tanaka, Takuya Oishi, Fumiya Yoneyama, Tomoko Hamaya, Kyo Togashi, Naoki Fujita, Teppei Okamoto, Chikara Ohyama, Shingo Hatakeyama

“…Results In total, 764.8 billion medications were recorded. Among these, standard dose‐adjusted prescriptions for bicalutamide, abiraterone, enzalutamide, apalutamide, darolutamide, and other vintages (estramustine phosphate, flutamide) was 276, 14.2, 18.1, 2.19, 0.34, and 20.3 million, respectively. …”
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Land cover change mitigated 20 % of the total increased evapotranspiration in tropical Lancang-Mekong River Basin during 2001–2019 by Houbing Chen, Yaoliang Chen, Lamin R. Mansaray, Longwei Li, Shusen Wang

“…LCCs caused a net reduction of 7.44 billion m³ in ET water consumption. This decrease in ET, may intensify the surface runoff and raise the risk of extreme floods in the rain season. …”
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Epidemiological trends and predictions of urinary tract infections in the global burden of disease study 2021 by Yining He, Jing Zhao, Lanhui Wang, Chao Han, Ruxue Yan, Peiqi Zhu, Tianyang Qian, Siyao Yu, Xiaolin Zhu, Weiming He

“…From 1990 to 2021, the number of UTI cases increased by 66.45%, reaching 4.49 billion cases, with an ASIR of 5,531.88 per 100,000 population. …”
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Cost-effectiveness and budget impact analysis of peritoneal dialysis and haemodialysis in South Africa by Evelyn Thsehla, Micheal Kofi Boachie, Susan Goldstein

“…The budget impact analysis showed that it would cost government approximately R25 billion over 5 years to treat all individuals eligible for KRT under the current scenario of 88% HD and 12% PD. …”
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Detection of Dengue Virus-Specific IgM and IgG Antibodies through Peptide Sequences of Envelope and NS1 Proteins for Serological Identification by Pradeep Kumar Nagar, Deepali Savargaonkar, Anupkumar R. Anvikar

“…At present, there is no particular treatment or vaccine candidate available for dengue infection. Approximately 3.9 billion human populations are at risk of dengue virus (DENV) infection. …”
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A systematic review of the environmental and health effects of waste tires recycling by Masoumeh Hashamfirooz, Mohammad Hadi Dehghani, Mohammad Khanizadeh, Mina Aghaei, Parnia Bashardoost, Mohammad Sadegh Hassanvand, Mohammad Hassanabadi, Fatemeh Momeniha

“…Objectives: With approximately 1.5 billion tires produced annually, the management and disposal of waste tires pose significant environmental challenges worldwide. …”
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Prevalence of Active Trachoma and Associated Factors in Areka Town, South Ethiopia, 2018 by Melese Menta Alambo, Eyasu Alam Lake, Shimelash Bitew Workie, Addisu Yeshambel Wassie

“…Background. Globally, 1.2 billion people live in trachoma endemic areas, 40.6 million people are suffering from active trachoma, and 48.5% of the global burden of active trachoma is distributed in five countries including Ethiopia. …”
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Classification Based on the Support Vector Machine for Determining Operational Targets for Controlling Electricity Usage With Conventional Meters: A Case Study of Industrial and Bu... by Galih Arisona, Alief Pascal Taruna, Dwi Irwanto, Arif Bijak Bestari, Wildan Juniawan

“…In the dataset used for this research, losses from confirmed electricity theft amounted to approximately IDR 19 billion. This research aims to improve the detection of electricity theft through a machine learning-based model utilizing the Support Vector Machine (SVM) classification technique. …”
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Carbon circular utilization and sequestration in depleted hydrocarbon reservoirs: Towards a carbon-neutral China by Lin Wu, Zhengmeng Hou, Yang Li, Weidong Wang, Long Cheng, Junzhang Lin, Zhifeng Luo, Liangchao Huang

“…A preliminary assessment indicates that CCCUS holds significant developmental potential in China, with 661 million tonnes of CO2 utilized per cycle and 3.47 billion tonnes ultimately sequestered. However, there is a significant lack of research on the core technology of CCCUS, specifically CO2 underground bio-methanation, in China. …”
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New sources of agriculturally valuable traits in hemp from the VIR collection for cultivar development by S. V. Grigoryev

“…The import of textiles to Russia has been observed to grow continuously, reaching $8.96 billion in 2016–2017. The present industrial hemp production in Russia is still a source of textile yarn, integrated in the industrial turnover of goods in the Russian Federation. …”
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Psychological distress in adolescence and later economic and health outcomes in the United States population: A retrospective and modeling study. by Nathaniel Z Counts, Noemi Kreif, Timothy B Creedon, David E Bloom

“…We found that the hypothetical policy could lead to $52 (95% credible interval [51,54]) billion USD in federal budget benefits over 10 years from labor supply impacts alone. …”
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The Impact of Sanctions’ Reduction and the Financial Strength of Companies on the Development of Garment Exports, Considering the Mediation Role of Direct and Indirect Exports. by Farshad Alidaei, Mostafa Hashemi Tilehnouei, hossein vazifedoost

“…Direct exports play a mediation role on the relationship between the Sanctions’ Reduction and the development of garment exports, the mediation role of indirect exports on the relationship between the Sanctions’ Reduction and the development of garment exports was also confirmed.Extended AbstractIntroductionA review of the latest statistical report on world trade, which was recently published by the World Trade Organization, shows that the dollar value of the world's textile and clothing exports was 315 billion and 505 billion dollars respectively in 2018, the ratio of the previous year increased 6.4 and 1.11 respectively, the increase was the fastest growth in the world's textile and apparel trade since 2012. …”
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Spaced Seed Data Structures for De Novo Assembly by Inanç Birol, Justin Chu, Hamid Mohamadi, Shaun D. Jackman, Karthika Raghavan, Benjamin P. Vandervalk, Anthony Raymond, René L. Warren

“…Many scalable assembly algorithms use the de Bruijn graph (DBG) paradigm to reconstruct genomes, where a table of subsequences of a certain length is derived from the reads, and their overlaps are analyzed to assemble sequences. …”
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Molecular Mechanisms and Therapeutic Prospects of Immunotherapy and Targeted Therapy in Primary Central Nervous System Lymphoma by Lin Zhong MM, Anqing Lu MB, Xiyue Lu MM, Xiaoyin Liu MD, Lujia Cao MM, Shihong Zhu MM, SiJun Diao MM, Xu Cheng MM, Hongwei Wu MB, Jing Chen MD

“…With a deeper understanding of the pathophysiology of PCNSL, various therapies, including CD20 monoclonal antibodies, Bruton's tyrosine kinase (BTK) inhibitors, immunomodulatory drugs, immune checkpoint inhibitors, phosphoinositide 3-kinase (PI3 K)/mammalian target of rapamycin(mTOR) inhibitors, and chimeric antigen receptor (CAR) -T cells are increasingly being applied and have demonstrated considerable efficacy. …”
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The Development and Applications of a Dual Optical Imaging System for Studying Glioma Stem Cells by Po-An Tai MD, PhD, Yen-Lin Liu MD, PhD, Ya-Ting Wen MD, Chien-Min Lin MD, PhD, Thanh-Tuan Huynh MD, PhD, Michael Hsiao DVM, PhD, Alexander T. H. Wu PhD, Li Wei MD, PhD

“…Additionally, we identified and isolated CD133+/GFP+ cells with increased tumorigenic properties, stemness markers, Notch1, β-catenin, and Bruton’s tyrosine kinase (Btk). Furthermore, prolonged temozolomide (TMZ) treatment enriched GSCs (reflected by increased percentage of CD133+ cells). …”
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Role of the Btk-PLCγ2 Signaling Pathway in the Bone Destruction of Apical Periodontitis by Lina Wang, Hong Zhang, Ming Dong, Meina Zuo, Shuo Liu, Ying Lu, Weidong Niu

“…Studies have shown that the Bruton tyrosine kinase- (Btk-) phospholipase Cγ2 (PLCγ2) signaling pathway plays an important role in bone absorption, but it is unknown whether it plays a role in apical periodontitis bone destruction. …”
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Case report: A panorama gene profile of ovarian cancer metastasized to axillary lymph node by Yu Xia, Yu Huang, Zheng Liu, Siyuan Song, Yi Wang, Yi Wang, Jing Luo

“…Further analysis of NGS identified two novel missense mutations, D326E in BTK (Bruton’s tyrosine kinase) at SH2 domain and D251E in EPHA5 (EPH receptor A5), along with other known cancer- associated mutations. …”
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The Role of Gut Microbiota in Hypertension Management - A Review by Alicja Kot, Marta Wojtczak, Natalia Myśliwiec, Adrian Różycki, Michał Pniak, Paweł Miklis, Maciej Mawlichanów, Aleksandra Ciesielska, Aleksandra Sieradzka, Krzysztof Szerej

“…According to the World Health Organization (WHO), hypertension affects approximately 1.13 billion people worldwide, contributing significantly to global morbidity and mortality. …”
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