A scalable tool for analyzing genomic variants of humans using knowledge graphs and graph machine learning by Shivika Prasanna, Ajay Kumar, Deepthi Rao, Eduardo J. Simoes, Praveen Rao

“…We tested VariantKG for KG construction by using 1,508 genome sequences, leading to 4 billion RDF statements. We evaluated GML tasks using VariantKG by selecting a subset of 500 sequences from the KG and performing node classification using well-known GML techniques such as GraphSAGE, Graph Convolutional Network (GCN) and Graph Transformer. …”
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Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System by Fernanda C. Paccola Mesquita, Camila Hochman-Mendez, Jacquelynn Morrissey, Luiz C. Sampaio, Doris A. Taylor

“…The number of high-quality cells required for engineering an adult human-sized bioartificial organ is greater than one billion. Until the emergence of induced pluripotent stem cells (iPSCs), autologous cell sources of this magnitude and with the required complexity were not available. …”
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A Review of Sustainable Water Practices: Teaching High School Students to Manage and Purify Water for Daily Needs by Wisnu Prayogo, Muhammad Faris Ihsan, Fajriharish Nur Awan, Nurul Mawaddah, Zhilli Izzadati Khairuni, Harry Wibowo, Liana Atika, Trimailuzi, Naufal Tinov, Sarra Rahmadani, Fatimah Maulida, Mena Fadillia Lukman

“…It also highlights the pressing global issue of water scarcity, noting that over 2 billion people still rely on unsafe drinking water sources. …”
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Computational Methods for Information Processing from Natural Language Complaint Processes—A Systematic Review by J. C. Blandón Andrade, A. Castaño Toro, A. Morales Ríos, D. Orozco Ospina

“…The specialized literature mentions that enterprises lost USD 75 billion due to poor customer service, highlighting that companies need to know and understand customer perceptions, especially emotions, and product reviews to gain insight and learn about customer feedback because of the importance of the voice of the customer for an organization. …”
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The Physics Case for an Electron-Muon Collider by Meng Lu, Andrew Michael Levin, Congqiao Li, Antonios Agapitos, Qiang Li, Fanqiang Meng, Sitian Qian, Jie Xiao, Tianyi Yang

“…The cost should vary from order 100 million to a few billion dollars, corresponding to different stages, which make the funding situation more practical.…”
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A Study Exploring Relationship between Risk Factors and Resilience among Youth by Fenny Leferty Kharpuri, Ramya Bhaskar

“…Background: “Youth” is best understood as a period of transition from the dependence of childhood to adulthood’s independence. Of the 1.2 billion people live in India, 54% are <24 years of age. …”
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Patch-Level and Neighborhood-Dependency Spatial Optimization Method (PNO): Application to Urban Land-Use Planning to Facilitate Both Socio-Economic and Environmental Development in... by Yuhan Cheng, Xiuyuan Zhang, Qi Zhou, Xiaoyan Dong, Shihong Du

“…Experiments were conducted in the urban area of Beijing, and the results suggested that, after optimization, the population and GDP can be improved by 667,323 people (4.72%) and USD 10.69 billion in products (2.75%) in the study area; meanwhile, the land surface temperature can be reduced by 0.12 °C (−0.32%). …”
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Comparing Prednisone and Methotrexate to Off-label Biologic Infliximab for Management of Ocular Uveitis: A Cost-minimization Analysis by William V. Padula, Miguel Cordero-Coma, Taygan Yilmaz, William V. Padula, Michéal J. Gallagher, Jonathan D. Campbell

“…Incurred clinical costs and lost productivity related to vision loss in these cases totals $3.58 billion annually. **Objective:** To evaluate whether infliximab, a modern off-label biologic, is cost-effective for treating posterior uveitis and panuveitis compared to current standards of care, methotrexate and prednisone. …”
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Artificial intelligence-driven ensemble deep learning models for smart monitoring of indoor activities in IoT environment for people with disabilities by Munya A. Arasi, Hussah Nasser AlEisa, Amani A. Alneil, Radwa Marzouk

“…The transformative latent of the Internet of Things (IoT) prolongs the existence of nearly one billion persons worldwide with disabilities. By incorporating smart devices and technologies, the IoT provides advanced solutions to tackle numerous tasks challenged by individuals with disabilities and promote equality. …”
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Evaluating ChatGPT-4's performance on oral and maxillofacial queries: Chain of Thought and standard method by Kaiyuan Ji, Zhihan Wu, Jing Han, Guangtao Zhai, Guangtao Zhai, Jiannan Liu

“…ObjectivesOral and maxillofacial diseases affect approximately 3.5 billion people worldwide. With the continuous advancement of Artificial Intelligence technologies, particularly the application of generative pre-trained transformers like ChatGPT-4, there is potential to enhance public awareness of the prevention and early detection of these diseases. …”
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Validation of a one-step reverse transcription PCR detection method for Tobamovirus maculatessellati, in tomato (Solanum lycopersicum L.) and pepper (Capsicum annuum L.) by Chellappan Padmanabhan, Andrea Gilliard, Kai-Shu Ling, Yazmín Rivera

“…Species-specific identification is crucial to prevent the entry and establishment of plant pathogens and protect the billion-dollar tomato industry. In this study, we report the validation of a previously described reverse transcription polymerase chain reaction (RT-PCR) assay that amplifies a 289 bp fragment of the coat protein coding region of ToMMV genome. …”
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Analysis of Air Quality and Health Co-Benefits under Low Carbon Pathway in Taiwan by Hsin-Chih Lai, Shih-Ming Chung, Li-Ling Li, Wen-Yinn Lin, Min-Chuan Hsiao

“…The reduction of air pollution can prevent 1012 (374–2463) deaths, saving around 48.9 billion NTD in health monetary costs. In the short term, it is projected that there may be a decrease of 45 patients hospitalized due to respiratory diseases and 53 patients hospitalized due to cardiovascular diseases. …”
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A community-based study to estimate the internet usage and its associated factors among elderly residing in an urban slum area in North India by Garima Sangwan, Nitika Sharma, Rajesh Garg

“… Background There has been tremendous growth in internet usage globally, with an estimated 5 billion users around the world in 2022 (1). In India , there were 840 million internet users in 2022 (2). …”
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The role of CGIAR Germplasm Health Units in averting endemic crop diseases: the example of rice blast in Bangladesh by Yuji Enriquez, Melinda Smale, Nelissa Jamora, Mohammod Hossain, Lava Kumar

“…In the most optimistic conditions (maximum), the IRRI GHU contributed as much as US$ 62 million of the US$ 1.46 billion benefits. The modal benefit–cost ratio of the GHU in this breeding program alone was estimated at 112. …”
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Briquetting of Dry Sugarcane Leaves by Using Press Mud, Cow Dung, and Buffalo Dung as Binders by Rahul A. Patil, Umesh B. Deshannavar, M. Ramasamy, Sampath Emani, Alibek Issakhov, Nima Khalilpoor

“…It is estimated that energy will need to be provided to 9 to 10 billion people by 2040. India is a leading consumer of energy in the world. …”
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Land Use Modeling and Predicted Ecosystem Service Value Under Different Development Scenarios: A Case Study of the Upper–Middle Yellow River Basin, China by Mingwei Ma, Yuhuai He, Yanwei Sun, Huijuan Cui, Hongfei Zang

“…Under three different scenarios, the regional <i>ESV</i>s are estimated at from CNY 2475 to 2710 billion, while grasslands contribute the largest part accounting for from 57.98% to 59.21%. …”
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Real-time detection and monitoring of public littering behavior using deep learning for a sustainable environment by Eaman Alharbi, Ghadah Alsulami, Sarah Aljohani, Waad Alharbi, Somayah Albaradei

“…Abstract With the global population surpassing 8 billion, waste production has skyrocketed, leading to increased pollution that adversely affects both terrestrial and marine ecosystems. …”
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Integrating Renewable Energy with Internet of Things (IoT): Pathways to a Smart Green Planet by Shojib Mia, Firoz Ahmed, Ibrahim Khan, Md. Emamul Kabir, Mehedi H. Roni, Khadijatul Cobra, Anjuman Ara Khatun, Shahriar Mahmud

“…IoT device adoption is rapidly increasing, with a projected 13% growth in 2024, bringing the total to 18.8 billion devices globally. However, there is a critical need for advanced applications of IoT technology, improved sensors implementation, and up-to-date software development to control IoT devices which is essential to fully harness renewable energy and combat global warming, ultimately achieving the vision of a smart green planet. …”
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With big data comes big responsibility: Strategies for utilizing aggregated, standardized, de‐identified electronic health record data for research by Veronica R. Olaker, Sarah Fry, Pauline Terebuh, Pamela B. Davis, Daniel J. Tisch, Rong Xu, Margaret G. Miller, Ian Dorney, Matvey B. Palchuk, David C. Kaelber

“…Currently, sources are available that offer insight into the health histories of well over a quarter of a billion people. Their use, however, is fraught with hazards, including introduction or reinforcement of biases, clarity of disease definitions, protection of patient privacy, definitions of covariates or confounders, accuracy of medication usage compared with prescriptions, the need to introduce other data sources such as vaccination or death records and the ensuing potential for inaccuracy, duplicative records, and understanding and interpreting the outcomes of data queries. …”
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Costs and Outcomes of Clostridioides difficile Infections in Germany: A Retrospective Health Claims Data Analysis by Katharina Schley, Kirstin Heinrich, Jennifer C. Moïsi, Dennis Häckl, Dominik Obermüller, Gordon Brestrich, Christof von Eiff, Thomas Weinke

“…Overall excess costs for CDI cases were estimated at approximately €1.6 billion within 1 year after diagnosis. Conclusions CDI in Germany is associated with a high clinical and economic burden, including significantly higher mortality, costs, and healthcare resource utilization, in patients with CDI versus their matched patients without CDI. …”
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