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  1. 461

    Consensus guidelines for the management of treatment-naïve chronic lymphocytic leukaemia in Singapore (2024) by Yeow Tee Goh, Yvonne Loh, Esther Chan, Yuh Shan Lee, Venkata Sreekanth Sampath, Daryl Tan, Shin Yeu Ong, Chandramouli Nagarajan

    Published 2025-01-01
    “…Due to the superior efficacy of targeted agents (Bruton's tyrosine kinase inhibitors [BTKis] and B-cell lymphoma 2 inhibitors [BCL2is]), sthese are favoured over standard chemotherapy or chemotherapy-immunotherapy, especially for patients with del(17p) or TP53 mutation, and less fit patients. …”
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  2. 462

    Ultrahigh Energy Neutrinos at the Pierre Auger Observatory by P. Abreu, M. Aglietta, M. Ahlers, E. J. Ahn, I. F. M. Albuquerque, D. Allard, I. Allekotte, J. Allen, P. Allison, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, R. Alves Batista, M. Ambrosio, A. Aminaei, L. Anchordoqui, S. Andringa, T. Antičić, C. Aramo, E. Arganda, F. Arqueros, H. Asorey, P. Assis, J. Aublin, M. Ave, M. Avenier, G. Avila, T. Bäcker, A. M. Badescu, M. Balzer, K. B. Barber, A. F. Barbosa, R. Bardenet, S. L. C. Barroso, B. Baughman, J. Bäuml, J. J. Beatty, B. R. Becker, K. H. Becker, A. Bellétoile, J. A. Bellido, S. BenZvi, C. Berat, X. Bertou, P. L. Biermann, P. Billoir, F. Blanco, M. Blanco, C. Bleve, H. Blümer, M. Boháčová, D. Boncioli, C. Bonifazi, R. Bonino, N. Borodai, J. Brack, I. Brancus, P. Brogueira, W. C. Brown, R. Bruijn, P. Buchholz, A. Bueno, R. E. Burton, K. S. Caballero-Mora, B. Caccianiga, L. Caramete, R. Caruso, A. Castellina, O. Catalano, G. Cataldi, L. Cazon, R. Cester, J. Chauvin, S. H. Cheng, A. Chiavassa, J. A. Chinellato, J. Chirinos Diaz, J. Chudoba, M. Cilmo, R. W. Clay, M. R. Coluccia, R. Conceição, F. Contreras, H. Cook, M. J. Cooper, J. Coppens, A. Cordier, S. Coutu, C. E. Covault, A. Creusot, A. Criss, J. Cronin, A. Curutiu, S. Dagoret-Campagne, R. Dallier, B. Daniel, S. Dasso, K. Daumiller, B. R. Dawson, R. M. de Almeida, M. De Domenico, C. De Donato, S. J. de Jong, G. De La Vega, W. J. M. de Mello Junior, J. R. T. de Mello Neto, I. De Mitri, V. de Souza, K. D. de Vries, L. del Peral, M. del Río, O. Deligny, H. Dembinski, N. Dhital, C. Di Giulio, M. L. Díaz Castro, P. N. Diep, F. Diogo, C. Dobrigkeit, W. Docters, J. C. D'Olivo, P. N. Dong, A. Dorofeev, J. C. dos Anjos, M. T. Dova, D. D'Urso, I. Dutan, J. Ebr, R. Engel, M. Erdmann, C. O. Escobar, J. Espadanal, A. Etchegoyen, P. Facal San Luis, H. Falcke, G. Farrar, A. C. Fauth, N. Fazzini, A. P. Ferguson, B. Fick, A. Filevich, A. Filipčič, S. Fliescher, C. E. Fracchiolla, E. D. Fraenkel, O. Fratu, U. Fröhlich, B. Fuchs, R. Gaior, R. F. Gamarra, S. Gambetta, B. García, S. T. Garcia Roca, D. Garcia-Gamez, D. Garcia-Pinto, A. Gascon Bravo, H. Gemmeke, P. L. Ghia, M. Giller, J. Gitto, H. Glass, M. S. Gold, G. Golup, F. Gomez Albarracin, M. Gómez Berisso, P. F. Gómez Vitale, P. Gonçalves, J. G. Gonzalez, B. Gookin, A. Gorgi, P. Gouffon, E. Grashorn, S. Grebe, N. Griffith, M. Grigat, A. F. Grillo, Y. Guardincerri, F. Guarino, G. P. Guedes, P. Hansen, D. Harari, T. A. Harrison, J. L. Harton, A. Haungs, T. Hebbeker, D. Heck, A. E. Herve, C. Hojvat, N. Hollon, V. C. Holmes, P. Homola, J. R. Hörandel, P. Horvath, M. Hrabovský, D. Huber, T. Huege, A. Insolia, F. Ionita, A. Italiano, C. Jarne, S. Jiraskova, M. Josebachuili, K. Kadija, K. H. Kampert, P. Karhan, P. Kasper, I. Katkov, B. Kégl, B. Keilhauer, A. Keivani, J. L. Kelley, E. Kemp, R. M. Kieckhafer, H. O. Klages, M. Kleifges, J. Kleinfeller, J. Knapp, D.-H. Koang, K. Kotera, N. Krohm, O. Krömer, D. Kruppke-Hansen, F. Kuehn, D. Kuempel, J. K. Kulbartz, N. Kunka, G. La Rosa, C. Lachaud, D. LaHurd, L. Latronico, R. Lauer, P. Lautridou, S. Le Coz, M. S. A. B. Leão, D. Lebrun, P. Lebrun, M. A. Leigui de Oliveira, A. Letessier-Selvon, I. Lhenry-Yvon, K. Link, R. López, A. Lopez Agüera, K. Louedec, J. Lozano Bahilo, L. Lu, A. Lucero, M. Ludwig, H. Lyberis, M. C. Maccarone, C. Macolino, S. Maldera, D. Mandat, P. Mantsch, A. G. Mariazzi, J. Marin, V. Marin, I. C. Maris, H. R. Marquez Falcon, G. Marsella, D. Martello, L. Martin, H. Martinez, O. Martínez Bravo, H. J. Mathes, J. Matthews, J. A. J. Matthews, G. Matthiae, D. Maurel, D. Maurizio, P. O. Mazur, G. Medina-Tanco, M. Melissas, D. Melo, E. Menichetti, A. Menshikov, P. Mertsch, C. Meurer, S. Mićanović, M. I. Micheletti, I. A. Minaya, L. Miramonti, L. Molina-Bueno, S. Mollerach, M. Monasor, D. Monnier Ragaigne, F. Montanet, B. Morales, C. Morello, E. Moreno, J. C. Moreno, M. Mostafá, C. A. Moura, M. A. Muller, G. Müller, M. Münchmeyer, R. Mussa, G. Navarra, J. L. Navarro, S. Navas, P. Necesal, L. Nellen, A. Nelles, J. Neuser, P. T. Nhung, M. Niechciol, L. Niemietz, N. Nierstenhoefer, D. Nitz, D. Nosek, L. Nožka, J. Oehlschläger, A. Olinto, M. Ortiz, N. Pacheco, D. Pakk Selmi-Dei, M. Palatka, J. Pallotta, N. Palmieri, G. Parente, E. Parizot, A. Parra, S. Pastor, T. Paul, M. Pech, J. Pękala, R. Pelayo, I. M. Pepe, L. Perrone, R. Pesce, E. Petermann, S. Petrera, A. Petrolini, Y. Petrov, C. Pfendner, R. Piegaia, T. Pierog, P. Pieroni, M. Pimenta, V. Pirronello, M. Platino, M. Plum, V. H. Ponce, M. Pontz, A. Porcelli, P. Privitera, M. Prouza, E. J. Quel, S. Querchfeld, J. Rautenberg, O. Ravel, D. Ravignani, B. Revenu, J. Ridky, S. Riggi, M. Risse, P. Ristori, H. Rivera, V. Rizi, J. Roberts, W. Rodrigues de Carvalho, G. Rodriguez, I. Rodriguez Cabo, J. Rodriguez Martino, J. Rodriguez Rojo, M. D. Rodríguez-Frías, G. Ros, J. Rosado, T. Rossler, M. Roth, B. Rouillé-d'Orfeuil, E. Roulet, A. C. Rovero, C. Rühle, A. Saftoiu, F. Salamida, H. Salazar, F. Salesa Greus, G. Salina, F. Sánchez, C. E. Santo, E. Santos, E. M. Santos, F. Sarazin, B. Sarkar, S. Sarkar, R. Sato, N. Scharf, V. Scherini, H. Schieler, P. Schiffer, A. Schmidt, O. Scholten, H. Schoorlemmer, J. Schovancova, P. Schovánek, F. Schröder, S. Schulte, D. Schuster, S. J. Sciutto, M. Scuderi, A. Segreto, M. Settimo, A. Shadkam, R. C. Shellard, I. Sidelnik, G. Sigl, O. Sima, A. Śmiałkowski, R. Šmída, G. R. Snow, P. Sommers, J. Sorokin, H. Spinka, R. Squartini, Y. N. Srivastava, S. Stanic, J. Stapleton, J. Stasielak, M. Stephan, A. Stutz, F. Suarez, T. Suomijärvi, A. D. Supanitsky, T. Šuša, M. S. Sutherland, J. Swain, Z. Szadkowski, M. Szuba, A. Tapia, M. Tartare, O. Taşcău, R. Tcaciuc, N. T. Thao, D. Thomas, J. Tiffenberg, C. Timmermans, W. Tkaczyk, C. J. Todero Peixoto, G. Toma, L. Tomankova, B. Tomé, A. Tonachini, P. Travnicek, D. B. Tridapalli, G. Tristram, E. Trovato, M. Tueros, R. Ulrich, M. Unger, M. Urban, J. F. Valdés Galicia, I. Valiño, L. Valore, A. M. van den Berg, E. Varela, B. Vargas Cárdenas, J. R. Vázquez, R. A. Vázquez, D. Veberič, V. Verzi, J. Vicha, M. Videla, L. Villaseñor, H. Wahlberg, P. Wahrlich, O. Wainberg, D. Walz, A. A. Watson, M. Weber, K. Weidenhaupt, A. Weindl, F. Werner, S. Westerhoff, B. J. Whelan, A. Widom, G. Wieczorek, L. Wiencke, B. Wilczyñska, H. Wilczyñski, M. Will, C. Williams, T. Winchen, M. Wommer, B. Wundheiler, T. Yamamoto, T. Yapici, P. Younk, G. Yuan, A. Yushkov, B. Zamorano Garcia, E. Zas, D. Zavrtanik, M. Zavrtanik, I. Zaw, A. Zepeda, Y. Zhu, M. Zimbres Silva, M. Ziolkowski

    Published 2013-01-01
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  3. 463

    Challenges and Economic Implications in the Control of Foot and Mouth Disease in Sub-Saharan Africa: Lessons from the Zambian Experience by Y. Sinkala, M. Simuunza, D. U. Pfeiffer, H. M. Munang’andu, M. Mulumba, C. J. Kasanga, J. B. Muma, A. S. Mweene

    Published 2014-01-01
    “…Impacts include losses in income of over US$ 1.6 billion from exports of beef and sable antelopes and an annual cost of over US$ 2.7 million on preventive measures. …”
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  4. 464

    Impact evaluation of hilsa fishery restoration in Bangladesh: money well spent? by Essam Yassin Mohammed, A. B. M. Mahfuzul Haque, Md. Nahiduzzaman

    Published 2025-01-01
    “…The hilsa fishery, Bangladesh’s largest single-species fishery, generates over USD 3 billion annually, contributing 12% to annual fish production and supporting 2.5 million people. …”
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  5. 465

    Evaluation of the Effect of Probiotic Bacillus coagulans Unique IS2 on Mutans Streptococci and Lactobacilli Levels in Saliva and Plaque: A Double-Blind, Randomized, Placebo-Control... by M. Ratna Sudha, Jayanthi Neelamraju, M. Surendra Reddy, Manoj Kumar

    Published 2020-01-01
    “…Probiotic Bacillus coagulans Unique IS2 (2 billion cfu) chewable tablet is effective in reduction and inhibition of caries causing mutans streptococci and lactobacilli levels in saliva and plaque in children.…”
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  6. 466

    Funding of activities of state veterinary services of Russian Federation Subjects by I. M. Klinovitskaya, M. A. Shibayev, A. K. Karaulov

    Published 2021-07-01
    “…In 2019, overall funding of the veterinary service of the country amounted to about 49.5 billion rubles which made up 96% of funding requirements for this period. …”
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  7. 467

    Techno-economic aspects of concrete lightweighting by char enrichment with phosphates from wastewater by Josef Marousek, Beata Gavurova, Anna Marouskova, Babak Minofar

    Published 2025-05-01
    “…Worldwide, biogas plants produce a billion tons of digestate daily. Proposed solutions involve dewatering, charring and activation of digestate that is subsequently used to sorb P from wastewater and used as a PC substitute. …”
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  8. 468

    Improvements in pig agriculture through gene editing by Kristin M. Whitworth, Jonathan A. Green, Bethany K. Redel, Rodney D. Geisert, Kiho Lee, Bhanu P. Telugu, Kevin D. Wells, Randall S. Prather

    Published 2022-06-01
    “…Given the need to sustainably improve animal production to feed an anticipated 9 billion global population by 2030 against a backdrop of infectious diseases and a looming threat from climate change, there is a pressing need for responsive, precise, and agile breeding strategies. …”
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  9. 469

    Ultrasound renal denervation in hypertensive patients: A systematic review and meta-analysis. by Roy Novri Ramadhan, Derren David Christian Homenta Rampengan, Felicia Angelica Gunawan, Nathania, Sebastian Emmanuel Willyanto, Hiroyuki Yamada, Mochammad Thaha, Satriyo Dwi Suryantoro, Maulana Antiyan Empitu

    Published 2025-01-01
    “…<h4>Introduction</h4>Hypertension is the leading noncommunicable disease case affecting 1.28 billion individuals worldwide, with most cases located in low- and middle-income countries. …”
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  10. 470

    Maintien du potentiel adaptatif chez les plantes domestiquées à propagation clonale by Doyle McKey, Marianne Elias, Benoît Pujol, Anne Duputié, Marc Delêtre, Delphine Renard

    Published 2012-11-01
    “…A shrub domesticated in Amazonia probably over 7000 years ago, manioc is today the staple food for over a billion people throughout the tropical world. It is propagated by farmers by stem cuttings : a small section of stem is cut from a mature plant and directly planted in the ground. …”
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  11. 471

    Sodium dichloroisocyanurate: a promising candidate for the disinfection of resilient drain biofilm by Abbie Martin, Natasha Doyle, Tom F. O'Mahony

    Published 2025-03-01
    “…Biofilms can cause a range of human diseases and are responsible for 1.7 million hospital-acquired infections in the US annually, providing an economic burden of $11.5 billion in treatment costs. Biofilm contained within drain and plumbing systems may contain pathogenic viruses and bacteria which pose a significant risk to patient safety within healthcare environments. …”
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  12. 472

    Action against birth defects: if not now, when? by Kathleen Strong, Judith Robb-McCord, Salimah Walani, Cecilia Mellado, Lorenzo D. Botto, Guillermo Lay-Son, Theresa Diaz, Tahmina Banu, Kokila Lakhoo, Anshu Banerjee

    Published 2024-12-01
    “…Demographic changes in sub-Saharan Africa portend a growing number of births with 1.6 billion projected from 2021 to 2050. More births and better survival without effective prevention and treatment for birth defects translates into more mortality and disability from birth defects. …”
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  13. 473

    Introducing reservoir sustainability indexing to investigate reservoir operations and piloting it at the basin of Lake Urmia with sparse data by Sina Sadeghfam, Navid Fahmfam, Rahman Khatibi, Brian Mark Crookston, Meysam Vadiati, Marjan Moazamnia

    Published 2025-02-01
    “…The subsequent knowledge discovery uncovers that: (i) Of 5.3 Billion Cubic Metres (BCM/Annum) lake inflows, 3.1 BCM/annum is required to maintain the lake, but cut off unwarrantedly, instigated the catastrophe. …”
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  14. 474

    Using ESPEN data for evidence-based control of neglected tropical diseases in sub-Saharan Africa: A comprehensive model-based geostatistical analysis of soil-transmitted helminths. by Jessie Jane Khaki, Mark Minnery, Emanuele Giorgi

    Published 2025-01-01
    “…<h4>Background</h4>The Expanded Special Project for the Elimination of Neglected Tropical Diseases (ESPEN) was launched in 2019 by the World Health Organization and African nations to combat Neglected Tropical Diseases (NTDs), including Soil-transmitted helminths (STH), which still affect over 1.5 billion people globally. In this study, we present a comprehensive geostatistical analysis of publicly available STH survey data from ESPEN to delineate inter-country disparities in STH prevalence and its environmental drivers while highlighting the strengths and limitations that arise from the use of the ESPEN data. …”
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  15. 475

    Sharing Economy for Cost Reduction and Efficiency Increase: The Case of Sharing E-Commerce Logistics by Qiang Wei, Daguang Sun, Xinyu Gou, Chunguang Bai

    Published 2021-01-01
    “…Confronted with the growing demand for e-commerce logistics express delivery, especially the urgent demand for tackling orders piling up to 1 billion pieces during the recent “Double 11” shopping carnival, it is very important and practical for us to study how to make scientific decisions on the supply side in the field of e-commerce express delivery. …”
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  16. 476

    Technological innovation, trade openness, natural resources, clean energy on environmental sustainably: a competitive assessment between CO2 emission, ecological footprint, load ca... by Jie Sun, Md. Qamruzzaman

    Published 2025-02-01
    “…Motivated by the urgent need to address escalating CO2 emissions—reaching 36.4 billion metric tons in 2022—the research aims to understand how these factors influence CO2 emissions, ecological footprint, load capacity factor, and its inverse, contributing to the Sustainable Development Goals (SDGs). …”
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  17. 477

    Search for CP violation in $${{{\textrm{D}}}^{{0}}} \rightarrow {{\textrm{K}} _{\text {S}}^{{0}}} {{\textrm{K}} _{\text {S}}^{{0}}} $$ D 0 → K S 0 K S 0 decays in proton–proton col... by CMS Collaboration

    Published 2024-12-01
    “…The analysis uses a dedicated data set that corresponds to an integrated luminosity of 41.6 $$\,\text {fb}^{-1}$$ fb - 1 , which consists of about 10 billion events containing a pair of b hadrons, nearly all of which decay to charm hadrons. …”
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  18. 478

    3D BIOPRINTING IN DENTISTRY: BIBLIOMETRIC ANALYSIS by Peter Frantsevich Litvitskiy, Alexander Tsymbal, Zhangirkhan Bolat, Yelaman Bazarbayev, Madina Bekentayeva, Raushan Nauryzbay, Azhar N. Zhexenova, Gulbanu Mukyshova, Lida Aliyeva, Aliya Zhylkybekova

    Published 2024-12-01
    “… Abstract  The World Health Organization (WHO) estimates that oral diseases affect about 3.5 billion people. According to the National Institute of Dental and Craniofacial Research Oral Health Surveillance Report, 2019, nearly 90% of adults between the ages of 20 and 64 had tooth decay, and this percentage did not change significantly between the NHANES 1999-2004 and 2011-2016 cycles. …”
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  19. 479

    Production and characterization of nervous necrosis virus vaccine antigens in wild type and CRISPR/Cas9 genome edited Nicotiana benthamiana and edible crop lettuce Lactuca sativa by Iva Andrasevic, Hang Su, Espen Rimstad, Jihong Liu Clarke

    Published 2025-03-01
    “…Disease outbreaks cause more than 6 billion USD loss worldwide annually and possess high risks of spreading to the wild fauna especially by viral infections. …”
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  20. 480

    Nutritional care for children with feeding difficulties and disabilities: A scoping review. by Alyssa Klein, Malia Uyehara, Andrew Cunningham, Madina Olomi, Kristen Cashin, Catherine M Kirk

    Published 2023-01-01
    “…One billion people worldwide have a disability, and 80 percent of them live in low- and middle-income countries (LMICs). …”
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