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Large-scale data mining of four billion human antibody variable regions reveals convergence between therapeutic and natural antibodies that constrains search space for biologics drug discovery
Published 2024-12-01“…AbNGS contains 135 bioprojects with four billion productive human heavy variable region sequences and 385 million unique complementarity-determining region (CDR)-H3s. …”
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Récits de vie et qualité paysagère : le point de vue de jardiniers
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Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia
Published 2023-09-01“…This study aims to determine in patients with chronic lymphocytic leukaemia (CLL) if a 3-week pause in Bruton tyrosine kinase inhibitor therapy (BTKi) starting 1 week before delivery of SARS-CoV-2 vaccine booster, improves vaccine immune response when compared with continuation of BTKi.Methods and analysis An open-label, randomised controlled superiority trial will be conducted in haematology clinics in approximately 10 UK National Health Service (NHS) hospitals. …”
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La mission de socialisation de l'école : enjeux et obstacles
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Bernard Lesfargues (1924-2018), entre fédéralisme européen et autonomisme occitan
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L’aqueduc du Gier à Lyon : la complexité de la protection au titre des monuments historiques
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Características étnico-raciales y desigualdad de oportunidades económicas en México
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Thesis-Building: Architecture, Alchemy and the Constructive Moment(s) of a Doctoral Dissertation
Published 2012-01-01Get full text
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Multi-Objective Optimization of Urban Air Transportation Networks Under Social Considerations
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Evidence for local inflammation in complex regional pain syndrome type 1
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Redox Potential and Its Control in Research and Commercial Wine Fermentations
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Stratégies d’acteurs et gouvernance des démarches d’écologie industrielle et territoriale
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Validation of the Hospitality Culture Scale in the context of hotel industry
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Functionality of the Search and Rescue Transponder (SART) in Maritime Search and Rescue Actions
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A Rationale for Going Back to the Future: Use of Disposable Spacers for Pressurised Metered Dose Inhalers
Published 2015-01-01Get full text
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