CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation. by John T Loffredo, Thomas C Friedrich, Enrique J León, Jason J Stephany, Denise S Rodrigues, Sean P Spencer, Alex T Bean, Dominic R Beal, Benjamin J Burwitz, Richard A Rudersdorf, Lyle T Wallace, Shari M Piaskowski, Gemma E May, John Sidney, Emma Gostick, Nancy A Wilson, David A Price, Esper G Kallas, Helen Piontkivska, Austin L Hughes, Alessandro Sette, David I Watkins

“…<h4>Background</h4>It is generally accepted that CD8+ T cell responses play an important role in control of immunodeficiency virus replication. …”
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Bibliotherapy Services in Public Libraries: the Case of Lithuania by Jurgita Girčienė, Miglė Damijonaitytė

“…Summarizing the data of the latest research presented in the article and previous secondary sources, it can be stated that in the early 21st century, library bibliotherapy began to be developed at the formal level, and after the development breakthrough recorded at the turn of the first and second decades it has already established itself as a service provided by Lithuanian public libraries. …”
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Development and progression association of various ophthalmic pathologies with the gut microbiome state (literature review) by G.N. Rezbaeva, A.E. Babushkin, O.I. Orenburkina, I.A. Gimranova

“…Nowadays, about 1150 species of microorganisms that can colonize the GIT have been identified, but no more than 20–30% of them can be cultivated. A huge study breakthrough of the gut microbiota species composition in a healthy person, as well as in persons with various pathologies, was obtained after a technique development for DNA sequencing. …”
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Assessing favipiravir impact on SARS-CoV-2 transmission within households: Insights from a multi-center study (FaviPrev) by Taweegrit Siripongboonsitti, Marisa Muadchimkaew, Kriangkrai Tawinprai, Ornisa Issaranon, Wichuda Meepholkij, Pureepat Arttawejkul, Apiradee Vararungzarit, Onwalee Dhissayakamol, Wilaiporn Preeyachit, Kamonwan Soonklang, Nithi Mahanonda

“…This breakthrough highlights its potential in broader public health strategies. …”
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In-situ/operando study of Cu-based nanocatalysts for CO2 electroreduction using electrochemical liquid cell TEM by Jiawei Wan, Jiawei Wan, Qiubo Zhang, Ershuai Liu, Ershuai Liu, Yi Chen, Yi Chen, Jiana Zheng, Jiana Zheng, Amy Ren, Walter S. Drisdell, Walter S. Drisdell, Haimei Zheng, Haimei Zheng

“…We highlight the platform’s crucial role in elucidating atomic-scale pathways of nanocatalyst restructuring and identifying catalytic active sites, as well as avoiding potential artifacts to ensure unbiased conclusions. …”
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Association among high blood pressure health literacy, social support and health-related quality of life among a community population with hypertension: a community-based cross-sec... by Ting Chen, Wei Gan, Li Song, Yujie Wang, Huan Qi, Qinghua Zhang, Jinyu Yin

“…Community intervention for hypertension management should consider HBP-HL promotion and social engagement as the breakthrough points to increase the impact on patients’ HRQoL.…”
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A class imbalance aware hybrid model for accurate rice variety classification by Hanumesh Vaidya, K.V. Prasad, C. Rajashekhar, D Tripathi, Renuka S, Jyoti Shetty, Kumar Swamy, Shobha Y

“…Rice classification plays a critical role in global agriculture, impacting the food security of over 3.5 billion people worldwide. …”
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Study of Modern Human Evolution via Comparative Analysis with the Neanderthal Genome by Musaddeque Ahmed, Ping Liang

“…Even though a number of comparisons have been made sporadically between Neanderthals and modern humans, mostly following a candidate gene approach, the major breakthrough took place with the sequencing of the Neanderthal genome. …”
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Scalable Fabrication of Light-Responsive Superhydrophobic Composite Phase Change Materials via Bionic-Engineered Wood for Solar–Thermal Energy Management by Yang Meng, Jiangyu Zhang, Yuchan Li, Hui Jiang, Delong Xie

“…This superhydrophobicity plays a critical role in preventing PCM leakage and enhancing environmental adaptability, ensuring long-term stability under diverse conditions. …”
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Soviet Researchers on the Middle East: Ahead of Their Time by I. D. Zvyagelskaya

“…The article attempts to consider some breakthrough ideas and assessments of historical events in the Middle East put forward by the Soviet experts. …”
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Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer by Yaojun Ren, Min Xue, Xinhui Hui, Xiuyu Liu, Muhammad Asad Farooq, Yiran Chen, Yuzhou Ji, Yixin Duan, Iqra Ajmal, Jie Yao, Wenzheng Jiang

“…Natural killer (NK) cells play a crucial role in the body’s anti-cancer defense, and chimeric antigen receptor (CAR)–NK cell therapy is gaining attention as a cutting-edge and promising treatment method. …”
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UPDATE ON CYTOMEGALOVIRUS INFECTION MANAGEMENT IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS by José Luis Piñana, Estela Giménez, Lourdes Vázquez, María Ángeles Marcos, Manuel Guerreiro, Rafael Duarte, Ariadna Pérez, Carlos de Miguel, Ildefonso Espigado, Marta González-Vicent, María Suarez-Lledó, Irene García-Cadenas, Rodrigo Martino, Angel Cedillo, Monserrat Rovira, Rafael de la Cámara, David Navarro, Carlos Solano

“…Strategies for tailoring LMV prophylaxis, managing breakthrough DNAemia, and implementing secondary prophylaxis in refractory cases were outlined. …”
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Unraveling the impact of SARS-CoV-2 mutations on immunity: insights from innate immune recognition to antibody and T cell responses by Rafael Bayarri-Olmos, Rafael Bayarri-Olmos, Adrian Sutta, Adrian Sutta, Anne Rosbjerg, Anne Rosbjerg, Mie Mandal Mortensen, Charlotte Helgstrand, Per Franklin Nielsen, Laura Pérez-Alós, Beatriz González-García, Laust Bruun Johnsen, Finn Matthiesen, Thomas Egebjerg, Cecilie Bo Hansen, Alessandro Sette, Alessandro Sette, Alba Grifoni, Ricardo da Silva Antunes, Peter Garred, Peter Garred

“…This immune escape has led to waves of breakthrough infections, raising questions about the efficacy and durability of immune protection. …”
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AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist by Rahul Brahma, Sunghyun Moon, Jae-Min Shin, Kwang-Hwi Cho

“…Abstract G protein-coupled receptors (GPCRs) play vital roles in various physiological processes, making them attractive drug discovery targets. …”
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Potential drug targets for asthma identified through mendelian randomization analysis by Xingxuan Chen, Yu Shang, Danting Shen, Si Shi, Zhe Wen, Lijuan Li, Hong Chen

“…Abstract Background The emergence of new molecular targeted drugs marks a breakthrough in asthma treatment, particularly for severe cases. …”
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DGAT1 Expression Promotes Ovarian Cancer Progression and Is Associated with Poor Prognosis by Leilei Xia, Ye Wang, Shengyun Cai, Mingjuan Xu

“…Diacylglycerol O-acyltransferase 1 (DGAT1) can synthesize triglycerides by transferring acyl-CoA to diacylglycerol, which plays a key role in lipid synthesis. However, the role of DGAT1 in ovarian cancer is not yet elucidated. …”
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Editorial by Teddy Surya Gunawan

“…Let us embrace these breakthroughs as stepping stones to a brighter, more sustainable future.   …”
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MANAGEMENT OF TRAINING ACTIVITIES AT POLITICAL SCHOOLS IN THE NORTH CENTRAL REGION TO MEET THE STANDARDS OF POLITICAL SCHOOLS by Vuong Quang Minh, Thai Van Thanh

“…Managing training activities is both a core mission of political schools and a pivotal tool to create breakthroughs in enhancing the quality of decentralized training programs. …”
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L’embouchure de l'Amazone, macro-frontière géomorphologique : enseignements de 30 années de recherches franco-brésiliennes sur les systèmes côtiers amazoniens (2e partie) by M. T. R. C. Prost, J-F. Faure, C. Charron, H.V. Borges, V. F. Santos, A.C. Mendes, A. Gardel

“…It refers to a large number of multidisciplinary scientific results, and to remote sensing breakthroughs in environmental monitoring. The main purpose of the Paper is to enlight the role of the Mouth as a threshold in regional and local dinamics and processes. …”
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Quantum Contextual Hypergraphs, Operators, Inequalities, and Applications in Higher Dimensions by Mladen Pavičić

“…Quantum contextuality plays a significant role in supporting quantum computation and quantum information theory. …”
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