Bisecting GlcNAc modification of vesicular GAS6 regulates CAFs activation and breast cancer metastasis by Jing Li, Xueting Ren, Lin Cao, Kaixiang Min, Meng Wang, Shuai Lin, Lei Lei, Zengqi Tan, Xiaoliang Cheng, Xiang Li, Feng Guan

“…Methods We assessed the correlation between bisecting GlcNAc levels and CAFs markers (α-SMA, PDGFRA, PDGFRB) in breast cancer tissues. …”
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Head and Neck Schwannomas: A Surgical Challenge—A Series of 5 Cases by Ishtyaque Ansari, Ashfaque Ansari, Arjun Antony Graison, Anuradha J. Patil, Hitendra Joshi

“…Schwannomas, also known as neurilemmomas, are benign peripheral nerve sheath tumors. They originate from any nerve covered with schwann cell sheath. …”
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Two Novel CYP11B1 Gene Mutations in Patients from Two Croatian Families with 11β-Hydroxylase Deficiency by Katja Dumic, Tony Yuen, Zorana Grubic, Vesna Kusec, Ingeborg Barisic, Maria I. New

“…Here, we describe the molecular genetics of two previously reported male siblings in whom diagnosis of 11β-OHD has been established based on their hormonal profiles displaying high levels of 11-deoxycortisol and hyperandrogenism. …”
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Partial AUCs in Long-Acting Injectables: Rationale, Challenges, Variability, Usefulness, and Clinical Relevance by Georgia Tsakiridou, Maria-Faidra-Galini Angelerou, Panagiotis Efentakis, Antonios Margaritis, Antigoni-Maria Papanastasiou, Lida Kalantzi

“…Regulatory authorities typically require bioequivalence to be demonstrated by comparing pharmacokinetic parameters like area under the plasma concentration-time curve (AUC) and maximum plasma concentration (C_max). Because in certain cases, AUC and C_max alone may not be adequate to identify formulation differences in early and/or late segments of the dosing interval, partial AUCs (pAUCs) have been proposed as additional metrics to evaluate bioequivalence. …”
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Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein. by June Yao, Tu Cam Le, Claudine H Kos, Joel M Henderson, Phillip G Allen, Bradley M Denker, Martin R Pollak

“…We developed a "knockin" mouse model by replacing Actn4 with a copy of the gene bearing an FSGS-associated point mutation. We used cells from these mice to show increased degradation of mutant alpha-actinin-4, mediated, at least in part, by the ubiquitin-proteasome pathway. …”
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Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti-Inflammatory Properties by Suppressing MAPK/STATs Signaling Pathways and ROS Production by Zhang L, Liu Y, Wang H, Guo S, Lv J

“…Moreover, the affinities between ASB and the target proteins were verified by molecular docking analysis. …”
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Early Warning and Management Method of Abnormal Performance of Tourist Scenic Spots Assisted by Image Recognition Technology by Zhaozhen Song, Jing Lu

“…Many types of scenic spots have been developed in most areas. The development of scenic spots will affect the economic development level of a region, and it will also affect the living standards of local residents because the construction of scenic spots will consume a lot of financial and human resources. …”
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Cervical prolapse during labor: A case report by Adugnaw Bogale Worku, Molla Asnake Kebede, Abebe Agegn Wudineh, Adefris Getachew Techane, Mekuanint Dessie Lakew, Chuchu Arega Zeleke

“…It presents significant risks to both maternal and fetal health, and the optimal delivery method depends on the severity of prolapse, labor progression, and the well-being of both mother and baby.A 25-year-old woman presented at 38 weeks and 4 days of gestation with vaginal mass protrusion and pain on pushing down. …”
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UDP-Induced Phagocytosis and ATP-Stimulated Chemotactic Migration Are Impaired in STIM1−/− Microglia In Vitro and In Vivo by Hye Min Lim, Heo Woon, Jung Woo Han, Yoshihiro Baba, Tomohiro Kurosaki, Min Goo Lee, Joo Young Kim

“…STIM1 function in immune cell calcium signalling has been studied extensively; however, its role in microglia, innate immune cells in brain, has not been fully understood. …”
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Insights into <i>Solea senegalensis</i> Reproduction Through Gonadal Tissue Methylation Analysis and Transcriptomic Integration by Daniel Ramírez, Marco Anaya-Romero, María Esther Rodríguez, Alberto Arias-Pérez, Robert Mukiibi, Helena D’Cotta, Diego Robledo, Laureana Rebordinos

“…Differential methylation comparisons revealed the highest number of differently methylated CpGs between maturation stages, followed by rearing conditions, and lastly between sexes. …”
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Dielectric Properties and 3D-Printing Feasibility of UV-Curable Resin/Micron Ceramic Filler Composites by Yijia Fu, Wendong Li, Man Xu, Chao Wang, Liyuan Zhang, Guanjun Zhang

“…The experimental results show that spherical fillers with large particle sizes, smooth surfaces, and high permittivity are conducive for reducing the slurry viscosity, increasing curing depth and adjusting the composite’s permittivity over a wide range. We believe that the proposed strategy for material system establishment can improve the 3D printability of high-permittivity composites and promote other applications of the d-FGMs by the stereolithography technique.…”
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Unique North American isolates of severe metastatic hypervirulent Klebsiella pneumoniae strain infections with hepatic abscesses seen in young patients within Texas. by Junaid M Alam, Eric N Riha, Haris Ahmed, Hong M Thai, Kevin Garnepudi, Ramesh B Kesavan, Gnananandh Jayaraman, Anna Sangster, Dylan Curry, Heidi A Butz, Lori Smith, Maureen Vowles, Kelly F Oakeson, Erin L Young, Siva T Sarva

“…<h4>Main results</h4>2020CK-00441 belonged to ST23 type while 2021CK-00720 was a ST65 type isolate. …”
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Comparison of Antioxidant and Alpha-Glucosidase Inhibitory Properties of Moringa peregrina and Ferulago carduchorum Leaf Extracts and Microencapsulation of Superior Plant by Shiva Nouri, Maryam Moslehishad, Seyede Marzieh Hosseini, Mina Etemadi

“…Results of assessing total phenolic content (TPC) using the Folin-Ciocalteu method revealed a strong positive correlation between TPC with antioxidant activity (r = 0.94, p<0.05). …”
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Fortifying plant fortresses: siderophores in defense against Cercospora leaf spot disease in Vigna radiata L. by Anushree Kamath, Abhishek Sharma, Arpit Shukla, Arpit Shukla, Arpit Shukla, Paritosh Parmar, Dhara Patel

“…Siderophores, specialized iron-chelating molecules produced by Bacillus amyloliquefaciens D5, were investigated for their role in enhancing plant defense mechanisms against Cercospora canescens in mung bean (Vigna radiata L.). Siderophores were extracted and purified using Amberlite XAD-4 and applied to plants at concentrations of 5, 10, and 15 µg/mL, followed by pathogen inoculation. …”
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The Effects of Statin Dose, Lipophilicity, and Combination of Statins plus Ezetimibe on Circulating Oxidized Low-Density Lipoprotein Levels: A Systematic Review and Meta-Analysis o... by Tannaz Jamialahmadi, Fatemeh Baratzadeh, Željko Reiner, Luis E. Simental-Mendía, Suowen Xu, Andrey V. Susekov, Raul D. Santos, Amirhossein Sahebkar

“…Evaluation of funnel plot, Begg’s rank correlation, and Egger’s weighted regression tests were used to assess the presence of publication bias. …”
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A review of chemical viscosity reducers for heavy oil: Advances and application strategies by Chenhao Gao, Ruiying Xiong, Jixiang Guo, Wyclif Kiyingi, Hanxuan Song, Li Wang, Wenlong Zhang, Xiangwei Chen

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The New Normal in Pastoral Care: The Enduring Legacy of Media Appropriation in the Post-Pandemic Roman Catholic Church by Giulia Isetti, Michael de Rachewiltz, Harald Pechlaner

“…A comparison of the two waves of interviews shows that in the new normal, there has been an acceleration of the adoption of ICT and AI, primarily for internal communication purposes. …”
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A finite element model for biomechanical characterization of ex vivo peripheral nerve dysfunction during stretch by Nicholas C. Vasas, Adam M. Forrest, Nathaniel A. Myers, Michael B. Christensen, Jenny L. Pierce, Sidney M. Kaufmann, Kimberly B. Lanaghen, Randal C. Paniello, Julie M. Barkmeier‐Kraemer, Jonathan P. Vande Geest

“…To uncover the underlying mechanisms of peripheral nerve injury, our research aims to develop a relationship between biomechanical peripheral nerve damage and function through finite element modeling. …”
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The Global Burden of Polycystic Ovary Syndrome in Women of Reproductive Age: Findings from the GBD 2019 Study by Jiang B

“…Despite its significance, it has been largely overlooked in global health discussions, with persistently high prevalence and incidence rates. …”
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Metabolic Profile in a Cohort of Young Sicilian Patients with Klinefelter’s Syndrome: The Role of Irisin by Stefano Radellini, Valentina Guarnotta, Vincenzo Sciabica, Giuseppe Pizzolanti, Carla Giordano

“…Univariate analysis revealed an inverse correlation between irisin and ISI-Matsuda (r = −0.128; p=0.010). …”
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