High-Throughput Analysis of the T Cell Receptor Beta Chain Repertoire in PBMCs from Chronic Hepatitis B Patients with HBeAg Seroconversion by Yachao Qu, Yong Huang, Di Liu, Yinuo Huang, Zhiyi Zhang, Zhiqiang Mi, Xiaoping An, Yigang Tong, Jun Lu

“…Here, we demonstrate that the 4 patients expressed Vβ12-4 at the highest frequencies of 10.6%, 9.2%, 17.5%, and 7.5%, and Vβ28 was the second most common, with frequencies of 7.8%, 6.7%, 5.3%, and 10.9%, respectively. …”
Get full text

Efficacy and Safety of Sofosbuvir-Based Direct-Acting Antiviral Agents Treatment for Patients with Genotype 3/6 Hepatitis C Virus Infection by Yong-yu Mei, You-ming Chen, Yuan-kai Wu, Xiao-hong Zhang, Wen-xiong Xu

“…Baseline HCV RNA was 6.29 ± 0.89log10 IU/mL. The numbers of GT 3a, 3b, and 6a patients were 10, 12, and 32, respectively. …”
Get full text

Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis by Meng Wang, Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang, Minghao Lu, Zhengtao Hong, Junming Huang, Xiao Zhi

“…The significant correlation among ATP11B, CMTM6, and PD-L1 was confirmed in clinical samples of pancreatic cancer.Conclusions LTX-315 was first identified as a peptide drug inducing PD-L1 downregulation via ATP11B. …”
Get full text

Las potencialidades de las artes en proyectos pedagógicos feministas con infancias. Una alterotopía en el espacio escolar by Juana Viridiana Becerril Fernández

Subjects: Get full text

Raphaël Mathevet et Roméo Bondon, Sangliers, Géographies d’un animal politique, Actes Sud, Arles, 2022, 207 pages. by Richard Raymond

“…Développement Durable et Territoires…”
Get full text

A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD by Tristan X. McCallister, Colin K. W. Lim, Mayuri Singh, Sijia Zhang, Najah S. Ahsan, William M. Terpstra, Alisha Y. Xiong, M. Alejandra Zeballos C, Jackson E. Powell, Jenny Drnevich, Yifei Kang, Thomas Gaj

“…Abstract An abnormal expansion of a GGGGCC (G4C2) hexanucleotide repeat in the C9ORF72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two debilitating neurodegenerative disorders driven in part by gain-of-function mechanisms involving transcribed forms of the repeat expansion. …”
Get full text

A INTIMAÇÃO DA SENTENÇA PENAL CONDENATÓRIA AO RÉU SOLTO ASSISTIDO PELA DEFENSORIA PÚBLICA OU POR ADVOGADO DATIVO by Theodoro Ganzo Aydos

Subjects: “…Intimação da sentença condenatória…”
Get full text

Internal Judicial Independence in the EU and Ghosts from the Socialist Past: Why the Court of Justice Should Not Follow AG Pikamäe in Hann-Invest by Nika Bačić Selanec, Davor Petrić

Subjects: Get full text

Human Factors in AR-Enabled Human-Robot Collaboration for Fabrication-Centric Architectural Design Process: A Co-design Workshop Approach. by Wei Win Loy, Anthony Franze, Jared Donovan, Müge Teixeira, Matt Adcock, Markus Rittenbruch

“…By leveraging the adaptability, creativity, and design judgement of designers with the strength, repeatability, and design precision of robotic assistance, HRC has the potential to create a unified design-fabrication workflow. …”
Get full text

Aspectos da (des)proteção de crianças e adolescentes no Brasil uma leitura sobre as demandas dirigidas aos Conselhos Tutelares by Joana Garcia, Camila Oliveira

Subjects: Get full text

Safety evaluation of the food enzyme protein‐glutamine γ‐glutamyltransferase from the non‐genetically modified Streptomyces mobaraensis strain AE‐BTG by EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Monika Sramkova, Henk Van Loveren, Laurence Vernis, Jaime Aguilera, Magdalena Andryszkiewicz, Natalia Kovalkovicova, Giulio diPiazza, Yi Liu

Subjects: “…EC 2.3.2.13…”
Get full text

Estrategias, adaptación y ruinas. El despertar del arte chino contemporáneo y la búsqueda del diálogo (1978-2018) by Franco Cecchi

Subjects: “…Arte chino contemporáneo…”
Get full text

2003 Handbook of Employment Regulations Affecting Florida Farm Employers and Workers: Migrant and Seasonal Agricultural Worker Protection Act (MSPA) [Federal] by Leo C. Polopolus, Michael T. Olexa, Fritz Roka, Carol Fountain

Subjects: “…FE406…”
Get full text

Oxymatrine inhibits the development of radioresistance in NSCLC cells by reversing EMT through the DcR3/AKT/GSK-3β pathway by Jianming Tang, Yu Cao, Hong Zhang, Rui Wang

Subjects: Get full text

Casnati, María Gabriela. “La referencia al Timeo en Física IV 2.” Areté 25.2 (2013): 231-266. by Juan Diego Bogotá Johnson

“…Ideas y Valores…”
Get full text

IPCC AR5全球气候模式对杨楼流域气温模拟精度评价及预估

Get full text

基于标值更新通信量模型的ATM缓冲区信元丢失率分析方法 by 李骄阳, 刘贤德, 惠晓实

Get full text

Cannabis sativa extracts inhibit LDL oxidation and the formation of foam cells in vitro, acting as potential multi-step inhibitors of atherosclerosis development. by Bruno Musetti, Alejandra Kun, David Menchaca, Alejandra Rodríguez-Haralambides, Javier Varela, Leonor Thomson, Edward M Bahnson

“…The three cannabis extracts inhibited the oxidation of LDL by copper ions and the formation of foam cells by J774.1 cells challenged with oxLDL (ED50 5-12 μg mL-1). …”
Get full text

Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway by Bo Li, Yue Zhang, Runting Yin, Wei Zhong, Rui Chen, Jinchuan Yan

“…The aortic ring assay further demonstrated that CD137 signaling promoted ECc sprouting. Inhibition of VEGFR2 by siRNA or XL184 (cabozantinib) and inhibition of downstream signaling by LY294002 (inhibits AKT activation) and L-NAME (eNOS inhibitor) remarkably abolished proangiogenic effects of CD137 signaling both in vitro and ex vivo. …”
Get full text

Soil Parameter Mapping and Ad Hoc Power Analysis to Increase Blocking Efficiency Prior to Establishing a Long-Term Field Experiment by Doug Collins, Chris Benedict, Andy Bary, Craig Cogger

“…Compared to the west to east blocking pattern, the final blocking pattern chosen resulted in a 7-fold increase in power for OM and a 36% increase in power for weeds.…”
Get full text