NF-κB/AP-1-Targeted Inhibition of Macrophage-Mediated Inflammatory Responses by Depigmenting Compound AP736 Derived from Natural 1,3-Diphenylpropane Skeleton by Van Thai Ha, Heung Soo Beak, Eunji Kim, Kwang-Soo Baek, Muhammad Jahangir Hossen, Woo Seok Yang, Yong Kim, Jun Ho Kim, Sungjae Yang, Jeong-Hwan Kim, Yung Hyup Joo, Chang Seok Lee, Joonho Choi, Hong-Ju Shin, Sungyoul Hong, Song Seok Shin, Jae Youl Cho

“…Therefore, our results strongly suggest that AP736 is a potential anti-inflammatory drug due to its suppression of NF-κB-IKK/IκBα and AP-1-IRAK1/TAK1 signalling, which may make AP736 useful for the treatment of macrophage-mediated skin inflammation.…”
Get full text

Image dataset: UAV images and ground data of one ‘Bingo’ mandarin and two ‘Valencia’ orange rootstock trials conducted in FloridaAg Data CommonsAg Data Commons by Randall P. Niedz, Kim D. Bowman

“…The data will be useful for 1) visualizing the effects of different rootstock selections and varieties on scion growth, effects that may not be fully captured with single measure metrics; and 2) development of image analysis applications and segmentation algorithms that can extract data from the images that are suitable for replacing some or all the ground measures.…”
Get full text

Investigation on high-temperature creep behavior at 300 °C in laser-welded joints of a novel heat-resistant Al alloy of Al–12Ce-0.4Sc by Jie Ning, Chao Feng, Linjie Zhang

Subjects: Get full text

La difficile territorialisation de la gestion de l’eau au Burkina Faso : une lecture au filtre de la théorie de la proximité by Bio Mohamadou Torou, Liza Debevec, Dapola Évariste Constant Da

“…Développement Durable et Territoires…”
Get full text

Insights into corrosion behavior of AlCrFeTi and AlCrFeTiY coating for fuel cladding in static and flowing liquid lead bismuth at 550°C by Jingyi Liang, Wei Zhang, Qingyu Li, Ke Zhao, Jun Xiao, Jijun Yang, Shaoyu Qiu, Sheng Huang

“…Corrosion resistance of AlCrFeTi and AlCrFeTiY coatings were evaluated in static and flowing lead bismuth with oxygen-controlled precondition at 550 °C, both the oxygen concentration of static and flowing liquid lead bismuth was 1 × 10−5 wt%. …”
Get full text

Investigations on tensile fractography and wear characteristics of Al7075-Al2O3-SiC Hybrid Metal Matrix Composites routed through liquid metallurgical techniques by M. Ravikumar, H. N. Reddappa, R. Suresh, Y. S Ram Mohan, C. R. Nagaraja, E. R. Babu

Subjects: “…al7075…”
Get full text

Contribution au renouvellement des connaissances sur le château de Châteauvillain (Haute-Marne) : l’apport d’un diagnostic au « 14 rue de Penthièvre » by Vincent Marchaisseau, Geneviève Daoulas

Subjects: Get full text

Un site interactif au service d’une meilleure connaissance des urgences en France : Le numérique en santé au service des territoires vécus by Katerina Kononovich, Jean-Marc Macé

“…The relevant territory reference is represented in this research by the « lived territory ». This research paper also proposes a projection for 2025 and 2030 of the theoretical needs in medical demography of general practitioners in these operational territories, i.e., « lived territories », in metropolitan France.…”
Get full text

L’éducation au politique sur des questions socialement vives (QSV) liées au développement durable (DD) et aux objectifs de développement durable (ODD) by Alain Legardez, Maryse Cadet-Mieze, Agnieszka Jeziorski

Subjects: “…socially acute questions (SAQs)…”
Get full text

New Insight on the Sublethal Effect of Bt-Cry1Ab in <i>Spodoptera litura</i> (Fabricius): Tissular Distribution of Cry1Ab, Ultrastructural Alterations and the Lysosomal Response by Yan-Jue Wang, Ya-Qin Shen, Ying-Dan Xiao, Xue Yang, Shao-Peng Hao, Jian-Qiu Liu, Xiao-Xue Yang, Kazuei Mita, Ya-Jing Xu

Subjects: Get full text

Emulation of ARISTOTLE and ROCKET AF trials in real-world atrial fibrillation patients results in similar efficacy and safety as original landmark trials: insights from the GARFIELD-AF registry by Ralf E Harskamp, Karen Pieper, A John Camm, Ajay K Kakkar, Jelle C L Himmelreich, Saverio Virdone, Jean-Pierre Bassand, Frank Misselwitz, Freek W A Verheugt, Frank Cools, Harry Gibbs, Antônio C Pereira-Barretto

“…HRs (95% CI) for apixaban versus VKA among ARISTOTLE-eligible users were 0.57 (0.34 to 0.94) for stroke/systemic embolism, 0.76 (0.48 to 1.20) for major bleeding and 0.89 (0.70 to 1.12) for all-cause mortality. …”
Get full text

Colloque « Les Historiens africains-américains et l’écriture de l’histoire au xixe siècle et au début du xxe siècle, quel héritage ? » by Liess Benlalli, Lamia Dzanouni

Get full text

Gazzâlî’nİn mantık İlmİnİ meşrûlaştırmasının mantık tarİHİ açısından değerlendİrİlmesİ by Ferruh Özpilavcı

Subjects: Get full text

Al-5Er-Ti Master Alloy with Both Grain Refinement and Microalloying Effects by Jingrui Ma, Zhiguo Lei, Shengping Wen, Guang Yang, Wu Wei, Hui Huang, Zuoren Nie

Subjects: Get full text

Harry Callahan, « Variations ». Exposition à la Fondation Henri Cartier-Bresson du 7 septembre 2010 au 19 décembre 2010André Kertész, Rétrospective au musée du Jeu de Paume, du 28 septembre 2010 au 6 février 2011 by Jean Kempf

Get full text

Evaluation of Health Science Students&rsquo; Knowledge, Attitudes, and Practices Toward Artificial Intelligence in Northern Saudi Arabia: Implications for Curriculum Refinement and... by ALruwail BF, Alshalan AM, Thirunavukkarasu A, Alibrahim A, Alenezi AM, Aldhuwayhi TZA

Subjects: Get full text

Research on the oxidation sequence of Ni-Al-Pt alloy by combining experiments and thermodynamic calculations by Na Ta, Lijun Zhang, Qin Li

Subjects: Get full text

Challenging the curve: can ChatGPT-generated MCQs reduce grade inflation in pharmacy education by Dalia Almaghaslah

Subjects: “…AI…”
Get full text

Surveillance Following Hepatitis B Surface Antigen Loss: An Issue Requiring Attention by Shuai-Wen Huang, Hong Long, Jia-Quan Huang

Subjects: “…HBsAg loss…”
Get full text

AZİZ AUGUSTİNUS'TA TANRI'YA DUYULAN AŞK VE MUTLULUK İLİŞKİSİ by Seda Özdal

Subjects: Get full text