NEUROlogical Prognosis After Cardiac Arrest in Kids (NEUROPACK) study: protocol for a prospective multicentre clinical prediction model derivation and validation study in children... by Elizabeth S Draper, John Pappachan, Kent Thorburn, David Inwald, Richard Feltbower, Buvana Dwarakanathan, Patrick Davies, Kate Penny-Thomas, James Martin, Rum Thomas, Kevin P Morris, Roger Parslow, Timothy Thiruchelvam, Sophie Skellett, Hari Krishnan Kanthimathinathan, Victoria Hiley, Peter Barry, Sian Cooper, Rohit Saxena, Cormac Breatnach, Barnaby Robert Scholefield, Sarah Evans, Mirjam Kool, Alice J Sitch, Fang Smith, Yamuna Thiru, Richard Levin, Rachel Agbecko, James Weitz, Akash Deep, Sandra Gala-Peralta, Milly Lo, Rachael Barber, Stewart Reid, Siva Oruganti, Kalai Sadasivam, Mark Bebbington

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Empagliflozin Use Is Associated With Lower Risk of All-Cause Mortality, Hospitalization for Heart Failure, and End-Stage Renal Disease Compared to DPP-4i in Nordic Type 2 Diabetes... by Gisle Langslet, Thomas Nyström, Dorte Vistisen, Bendix Carstensen, Emilie Toresson Grip, Paula Casajust, Giorgi Tskhvarashvili, Fabian Hoti, Riho Klement, Kristina Karlsdotter, Mikko Tuovinen, Anne Pernille Ofstad, Maria Lajer, Christina Shay, Lisette Koeneman, Soulmaz Fazeli Farsani, Leo Niskanen, Sigrun Halvorsen

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SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocolsResearch in context by Moreno Ursino, Guillermo Villacampa, Jan Rekowski, Munyaradzi Dimairo, Olga Solovyeva, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Thomas R. Jeffry Evans, Elizabeth Garrett-Mayer, Robert M. Golub, Christina Guo, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Adrian Mander, Lynley V. Marshall, James Matcham, Dhrusti Patel, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Mahtab Rouhifard, Lesley Seymour, Yoshiya Tanaka, Christopher J. Weir, Johann de Bono, Christina Yap

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CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

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Author Correction: Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England by Pablo N. Perez-Guzman, Edward Knock, Natsuko Imai, Thomas Rawson, Cosmo Nazzareno Santoni, Joana Alcada, Lilith K. Whittles, Divya Thekke Kanapram, Raphael Sonabend, Katy A. M. Gaythorpe, Wes Hinsley, Richard G. FitzJohn, Erik Volz, Robert Verity, Neil M. Ferguson, Anne Cori, Marc Baguelin

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Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England by Pablo N. Perez-Guzman, Edward Knock, Natsuko Imai, Thomas Rawson, Cosmo Nazzareno Santoni, Joana Alcada, Lilith K. Whittles, Divya Thekke Kanapram, Raphael Sonabend, Katy A. M. Gaythorpe, Wes Hinsley, Richard G. FitzJohn, Erik Volz, Robert Verity, Neil M. Ferguson, Anne Cori, Marc Baguelin

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Clinical and cost-effectiveness of Knee Arthroplasty versus Joint Distraction for Osteoarthritis (KARDS): protocol for a multicentre, phase III, randomised control trial by Deborah D Stocken, Dennis G McGonagle, David Murray, Catherine Reynolds, Catherine Fernandez, David R Ellard, Andrew Metcalfe, Hemant Sharma, Paul Harwood, Hamish Simpson, Hemant Pandit, Susanne Arnold, Cerys Joyce Tassinari, Ruchi Higham, Isabelle Louise Smith, Ruben Mujica-Mota, Thomas William Hamilton, Julie Croft

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Limited Effect of Future Land‐Use Changes on Human Heat Stress and Labor Capacity by Steven J. DeHertog, Anton Orlov, Felix Havermann, Suqi Guo, Iris Manola, Julia Pongratz, Quentin Lejeune, Carl‐Friedrich Schleussner, Inga Menke, Florian Humpenöder, Alexander Popp, Peter Lawrence, George C. Hurtt, Louise Chini, Inne Vanderkelen, Edouard L. Davin, Thomas Reerink, Sonia I. Seneviratne, Hans Verbeeck, Wim Thiery

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V3+ extends the V3 framework to ensure user-centricity and scalability of sensor-based digital health technologies by Jessie P. Bakker, Roland Barge, Jacob Centra, Bryan Cobb, Chas Cota, Christine C. Guo, Bert Hartog, Nathalie Horowicz-Mehler, Elena S. Izmailova, Nikolay V. Manyakov, Samantha McClenahan, Stéphane Motola, Smit Patel, Oana Paun, Marian Schoone, Emre Sezgin, Thomas Switzer, Animesh Tandon, Willem van den Brink, Srinivasan Vairavan, Benjamin Vandendriessche, Bernard Vrijens, Jennifer C. Goldsack

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Activating Mutation (V617F) in the Tyrosine Kinase JAK2 is Absent in Locally-Confined or Castration-Resistant Prostate Cancer by Lei Gu, Xian-Hua Zhu, Tapio Visakorpi, Kalle Alanen, Tuomas Mirtti, Tina Bocker Edmonston, Marja T. Nevalainen

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Proteomic analysis of murine norovirus-infected Raw 264.7 cells reveals the induction of Ras GTPases by Sung Ho Yun, Md Arif-Ur Rahman, Soo-Bin Nam, Soo Hyeon Kim, Gyuri Kim, Kun Cho, Jong-Soon Choi

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Reconstructing the last common ancestor of all eukaryotes. by Thomas A Richards, Laura Eme, John M Archibald, Guy Leonard, Susana M Coelho, Alex de Mendoza, Christophe Dessimoz, Pavel Dolezal, Lillian K Fritz-Laylin, Toni Gabaldón, Vladimír Hampl, Geert J P L Kops, Michelle M Leger, Purificacion Lopez-Garcia, James O McInerney, David Moreira, Sergio A Muñoz-Gómez, Daniel J Richter, Iñaki Ruiz-Trillo, Alyson E Santoro, Arnau Sebé-Pedrós, Berend Snel, Courtney W Stairs, Eelco C Tromer, Jolien J E van Hooff, Bill Wickstead, Tom A Williams, Andrew J Roger, Joel B Dacks, Jeremy G Wideman

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The high-resolution map of Oxia Planum, Mars; the landing site of the ExoMars Rosalind Franklin rover mission by Peter Fawdon, Csilla Orgel, Solmaz Adeli, Matt Balme, Fred J. Calef, Joel M. Davis, Alessandro Frigeri, Peter Grindrod, Ernst Hauber, Laetitia Le Deit, Damien Loizeau, Andrea Nass, Cathy Quantin-Nataf, Elliot Sefton-Nash, Nick Thomas, Ines Torres, Jorge L. Vago, Matthieu Volat, Sander De Witte, Francesca Altieri, Andrea Apuzzo, Julene Aramendia, Gorka Arana, Rickbir Singh Bahia, Steven G. Banham, Robert Barnes, Alexander M. Barrett, Wolf-Stefan Benedix, Anshuman Bhardwaj, Sarah Jane Boazman, Tomaso R. R. Bontognali, John Bridges, Benjamin Bultel, Valérie Ciarletti, Maria Cristina De Sanctis, Zach Dickeson, Elena A. Favaro, Marco Ferrari, Frédéric Foucher, Walter Goetz, Albert F. C. Haldemann, Elise Harrington, Angeliki Kapatza, Detlef Koschny, Agata M. Krzesinska, Alice Le Gall, Stephen R. Lewis, Tanya Lim, Juan Manuel Madariaga, Benjamin James Man, Lucia Mandon, Nicolas Mangold, Javier Martin-Torres, Joseph D. McNeil, Antonio Molina, Andoni G. Moral, Sara Motaghian, Sergei Nikiforov, Nicolas Oudart, Andrea Pacifici, Adam Parkes Bowen, Dirk Plettemeier, Pantelis Poulakis, Alfiah Rizky Diana Putri, Ottaviano Ruesch, Lydia Sam, Christian Schröder, Christoph Statz, Rebecca Thomas, Daniela Tirsch, Zsuzsanna Toth, Stuart Turner, Martin Voelker, Stephanie C. Werner, Frances Westall, Barry J. Whiteside, Adam Williams, Rebecca M. E. Williams, Jack Wright, Maria-Paz Zorzano

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Clinical validation of an artificial intelligence-based decision support system for diagnosis and risk stratification of heart failure (STRATIFYHF): a protocol for a prospective, m... by Prithwish Banerjee, Guy A MacGowan, Frans H Rutten, Iacopo Olivotto, Petar M Seferović, Jonathan Mant, Djordje G Jakovljevic, Oscar Fernandez, Josep Darbà, Nduka C Okwose, Jose Zamorano, Duncan Edwards, David Sinclair, Lazar Velicki, Amy Groenewegen, Lars S Maier, Dimitris Fotiadis, Sarah Jane Charman, Annamaria Del Franco, Maria Tafelmeier, Andrej Preveden, Cristina Garcia Sebastian, Amy S Fuller, Anne Pauline Nelissen, Petros Malitas, Aikaterini Zisaki, Zoran Bosnic, Petar Vracar, Fausto Barlocco, Marta Jiménez-Blanco Bravo, Nenad Filipovic, Bano Fatima, Williams Kate, Fornaro Alessandra, Milovancev Aleksandra, Ascanio Meritxell, Aguera Ainoa, Pičulin Matej, Flis Borut, Boucharas Dimitrios, Manousos Dimitris, Tsiknakis Manolis, Kassiotis Thomas, Sustersic Tijana, Milicevic Bogdan, Hobbs FD Richard, Kaagman Onno

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Oxidative impact on lipoprotein structure: Insights from dynamic light scattering by Nickolette Kong, Natalia Penaloza, Gustavo Agreda, Angela B. Nguyen, Joseph Gutheinz, Alison Tran, Nhi Nguyen, Tuong Vi Ho, Ana Marin, Birgit Mellis, Richa Chandra

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The Ambivalent Representation of the Orient in T. E. Lawrence’s Seven Pillars of Wisdom: A Triumph (1935) by Sonia Lamrani

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Culture of Critical Discourse on Education and Science by M. B. Sapunov, Kh. G. Tkhagapsoev

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Dark matter influences on wormhole stability in de Rham–Gabadadze–Tolley like massive gravity by Jitendra Kumar, S. K. Maurya, Sweeti Kiroriwal

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A Critique on the Book Strategic Management and Business Policy-Environmental Analysis and Strategy Formulation by Amir Reza Konjkav Monfared

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A state-of-the-art review on the modeling and probabilistic approaches to analysis of power systems integrated with distributed energy resources by Paul Wanjoli, Nabil H. Abbasy, Mohamed M. Zakaria Moustafa

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