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Emerging roles of mitochondrial sirtuin SIRT5 in succinylation modification and cancer development
Published 2025-01-01“…Succinylation represents an emerging class of post-translational modifications (PTMs), characterized by the enzymatic or non-enzymatic transfer of a negatively charged four-carbon succinyl group to the ϵ-amino group of lysine residues, mediated by succinyl-coenzyme A. …”
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YELLOW CAMELLIAS: A REVIEW OF CHEMICAL CONSTITUENTS AND BIOLOGICAL ACTIVITIES
Published 2022-04-01“…Chemical and biological studies have only been carried out on a few species, with the main focus on the Chinese species Camellia nitidissima, but have shown that the main active ingredients of these yellow camellia species include flavonoids, phenolic compounds, saponins, triterpenoids, phytosterols, essential oils, amino acids, and polysaccharides. Many pharmacological studies have proved that the total extracts, fractions, and isolated substances from yellow camellia species possess antioxidant, anticancer, hypolipidemic, hypoglycemic, antiallergic, hepatoprotective, neuroprotective, anxiolytic, and antidepressant activities. …”
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Potential of germanium-based compounds in coronavirus infection
Published 2022-06-01“…They include germanium carboxylates and citrates, complexes of germanium with resveratrol, daphnetin, mangiferin, chrysin, quercetin, ascorbic and nicotinic acids, amino acids, gamma-lactones, germanium-containing spirulina, yeast and others. …”
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Characteristic Profiles of an Original Drink Sap from Male and Female Deglet Nour Palm (Phoenix dactylifera L.) during Collection Period
Published 2016-01-01“…Dry matter, protein, amino acids, and sugar profiles were determined using AFNOR norm, Kjeldahl method, HPLC, and HPAEC-PAD, respectively. …”
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The Dietary Use of Pigeon Pea for Human and Animal Diets
Published 2022-01-01“…Protein, carbohydrates, minerals, vitamins, and essential amino acids are all present in reasonable amounts in both mature and immature PP seeds. …”
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Synthesis, docking, pharmacokinetic prediction, and acetylcholinesterase inhibitory evaluation of N-(2-(piperidine-1-yl)ethyl)benzamide derivatives as potential anti-Alzheimer agen...
Published 2024-12-01“…Docking studies were also performed to investigate the binding mode and determine the interacting amino acids with the corresponding ligands. Finally, the pharmacokinetic (ADME parameters) of the most potent derivative (5d) was predicted and compared with donepezil. …”
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Lowering the affinity of single-chain monovalent BBB shuttle scFc-scFv8D3 prolongs its half-life and increases brain concentration
Published 2025-01-01“…Initially, in silico protein-protein docking analysis was performed to identify amino acids (AAs) likely to contribute to 8D3s TfR binding affinity. …”
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