-
41
Predicting conversion of Alzheimer’s disease based on multi-modal fusion of neuroimaging and genetic data
Published 2024-12-01“…Abstract Identifying progressive mild cognitive impairment (pMCI) and stable mild cognitive impairment (sMCI) play a significant role in the early diagnosis of Alzheimer’s disease (AD) and can be helpful in early treatment to reduce the risk of conversion to AD. …”
Get full text
Article -
42
Adapting to evolving MRI data: A transfer learning approach for Alzheimer’s disease prediction
Published 2025-02-01“…Integrating 3D magnetic resonance imaging (MRI) with machine learning has shown promising results in healthcare, especially in detecting Alzheimer’s Disease (AD). However, changes in MRI technologies and acquisition protocols often yield limited data, leading to potential overfitting. …”
Get full text
Article -
43
Detection of Alzheimer Disease in Neuroimages Using Vision Transformers: Systematic Review and Meta-Analysis
Published 2025-02-01“… BackgroundAlzheimer disease (AD) is a progressive condition characterized by cognitive decline and memory loss. …”
Get full text
Article -
44
Neurogranin in Alzheimer's Disease: Roles in synaptic function, pathology, and potential as a diagnostic biomarker
Published 2024-09-01“…Postsynaptic protein neurogranin (Ng), which plays a role in synaptic plasticity, learning, and memory, has been identified as the candidate biomarker of Alzheimer's disease (AD). Cortical Amyloid β pathology seems to accelerate the onset of clinical symptoms; therefore, it is potentially valuable for early diagnosis of AD and therapeutic intervention. …”
Get full text
Article -
45
The use of virtual reality in screening for preclinical Alzheimer's disease: A scoping review protocol.
Published 2023-01-01“…<h4>Introduction</h4>Preclinical Alzheimer's disease (AD) represents the earliest phase of AD, often years before the onset of mild cognitive impairment (MCI). …”
Get full text
Article -
46
Parkinson’s disease and exosomes: from pathogenesis to diagnosis and treatment
Published 2021-06-01“… Parkinson’s disease (PD) is considered the second most common neurodegenerative disease after Alzheimer’s disease, with a mean onset age of 55 years. …”
Get full text
Article -
47
Information Geometry and Manifold Learning: A Novel Framework for Analyzing Alzheimer’s Disease MRI Data
Published 2025-01-01“…<b>Background</b>: Alzheimer’s disease is a progressive neurological condition marked by a decline in cognitive abilities. …”
Get full text
Article -
48
Anti-Amyloid Imaging Abnormality in the Era of Anti-Amyloid Beta Monoclonal Antibodies: Recent Updates for the Radiologist
Published 2025-01-01“…This has increased interest in anti-amyloid immunotherapy for Alzheimer’s disease. Anti-amyloid immunotherapy has shown potential to modify the progression of the disease by specifically binding to amyloid β, a key pathological product in Alzheimer’s disease, and eliminating accumulated amyloid plaques in the brain. …”
Get full text
Article -
49
A research landscape analysis on Alzheimer's disease and gerontechnology: Identifying key contributors, hotspots, and emerging trends
Published 2025-03-01“…This paper presents a systematic bibliometric analysis of the research landscape at the intersection of Alzheimer's disease and gerontechnology, identifying key contributors, research hotspots, and emerging trends. …”
Get full text
Article -
50
Multimodal MRI Neuroimaging Biomarkers for Cognitive Normal Adults, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease
Published 2012-01-01“…These advantages have made MRI an important tool to investigate neurodegenerative disorders, including diagnosis, disease progression monitoring, and treatment efficacy evaluation. …”
Get full text
Article -
51
Identification of blood plasma protein ratios for distinguishing Alzheimer's disease from healthy controls using machine learning
Published 2025-02-01“…Liquid biopsy techniques, especially those involving plasma biomarkers, provide a promising noninvasive method for early diagnosis and disease monitoring. In this study, we analyzed the plasma proteomic profiles of 38 healthy individuals, with an average age of 66.5 years, and 22 patients with Alzheimer's disease, with an average age of 79.7 years. …”
Get full text
Article -
52
Interplay between oxidative stress, neuroinflammatory cytokines and melatonin in Alzheimer's disease: Insights from cerebrospinal fluid analysis
Published 2025-01-01“…Abstract: Background: Among neurodegenerative disorders Alzheimer's disease (AD) displays the highest prevalence and the projected increase in its incidence will require new advances in early diagnosis and treatment, particularly for distinguishing AD from other dementias. …”
Get full text
Article -
53
APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease
Published 2025-01-01“…Abstract The ApoE ε4 allele (APOEε4) is a major genetic risk factor for sporadic Alzheimer's disease (AD) and is linked to demyelination and cognitive decline. …”
Get full text
Article -
54
-
55
Alzheimer’s disease may develop from changes in the immune system, cell cycle, and protein processing following alterations in ribosome function
Published 2025-01-01“…Abstract The prevalence of Alzheimer’s disease (AD) is increasing as society ages. …”
Get full text
Article -
56
Identification of Alzheimer’s Disease Progression Stages Using Topological Measures of Resting-State Functional Connectivity Networks: A Comparative Study
Published 2022-01-01“…A total of 54 subjects from Alzheimer’s Disease Neuroimaging Initiative (ANDI) database, divided into healthy control (HC), mild cognition impairment (MCI), and AD groups, were included in this study. …”
Get full text
Article -
57
Enhanced detection of mild cognitive impairment in Alzheimer’s disease: a hybrid model integrating dual biomarkers and advanced machine learning
Published 2025-01-01“…Early diagnosis is the most effective strategy to slow the disease's progression. …”
Get full text
Article -
58
Sleep quality among sample of Egyptian patients with Alzheimer’s disease: risk factors and role of genetic profiling for ACE, ACE 2 and APO E genotypes
Published 2025-01-01“…Abstract Background Most individuals having Alzheimer’s disease generally experience increased frequency of awakenings as well as prolonged wakefulness periods at night. …”
Get full text
Article -
59
Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheimer’s disease: insights from machine learning analyses and WGCNA
Published 2025-01-01“…Abstract Background The mechanism of palmitoylation in the pathogenesis of Alzheimer's disease (AD) remains unclear. Methods This study retrieved AD data sets from the GEO database to identify palmitoylation-associated genes (PRGs). …”
Get full text
Article -
60
Integrating Data Mining, Deep Learning, and Gene Ontology Analysis for Gene Expression-Based Disease Diagnosis Systems
Published 2025-01-01“…To our mind, the implementation of this model promises to significantly improve the efficacy of early diagnosis systems for complex diseases.…”
Get full text
Article