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Age-Adjusted Schedules of Venetoclax and Hypomethylating Agents to Treat Extremely Elderly Patients with Acute Myeloid Leukemia
Published 2022-01-01“…Recently, the United States FDA has approved venetoclax, a selective oral BCL-2 inhibitor, for use in conjunction with hypomethylating agents (azacitidine or decitabine) or low-dose cytarabine as a first-line treatment option for those AML patients ineligible for standard induction chemotherapy. …”
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142
Large-scale post-disaster user distributed coverage optimization based on multi-agent reinforcement learning
Published 2022-08-01“…In order to quickly restore emergency communication services for large-scale post-disaster users, a distributed intellicise coverage optimization architecture based on multi-agent reinforcement learning (RL) was proposed, which could address the significant differences and dynamics of communication services caused by a large number of access users, and the difficulty of expansion caused by centralized algorithms.Specifically, a distributed k-sums clustering algorithm considering service differences of users was designed in the network characterization layer, which could make each unmanned aerial vehicle base station (UAV-BS) adjust the local networking natively and simply, and obtain states of cluster center for multi-agent RL.In the trajectory control layer, multi-agent soft actor critic (MASAC) with distributed-training-distributed-execution structure was designed for UAV-BS to control trajectory as intelligent nodes.Furthermore, ensemble learning and curriculum learning were integrated to improve the stability and convergence speed of training process.The simulation results show that the proposed distributed k-sums algorithm is superior to the k-means in terms of average load efficiency and clustering balance, and MASAC based trajectory control algorithm can effectively reduce communication interruptions and improve the spectrum efficiency, which outperforms the existing RL algorithms.…”
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143
Oral antihypertensive agents and diuretics in the management of hypertension in postpartum women: a systematic review and meta-analysis
Published 2024-12-01“…Objective In the puerperium, women with hypertensive disease of pregnancy remain at risk for maternal complications. The antihypertensive agent prescribed antepartum is usually continued postpartum; however, evidence regarding the most effective treatment is lacking. …”
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State-of-the-Art Management of Complications of Myeloma and Its Treatment
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Complications of tattoos and tattoos removal: state-of-the-art in Italy
Published 2016-07-01Get full text
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Adaptive Control for Multi-Agent Systems Governed by Fractional-Order Space-Varying Partial Integro-Differential Equations
Published 2024-12-01“…This paper investigates a class of multi-agent systems (MASs) governed by nonlinear fractional-order space-varying partial integro-differential equations (SVPIDEs), which incorporate both nonlinear state terms and integro terms. …”
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Could Infectious Agents Play a Role in the Onset of Age-related Macular Degeneration? A Scoping Review
Published 2025-03-01“…Topic: This scoping review aims to summarize the current state of knowledge on the potential involvement of infections in age-related macular degeneration (AMD). …”
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153
Towards more efficient, more specific, and safer MRI contrast agents: a Portuguese–French collaborative journey
Published 2025-01-01“…More recently, manganese porphyrin complexes have been investigated with the objective of visualizing the tissue redox state based on the Mn(II)/Mn(III) redox switch, which can be followed not only in classical 1H detection but also in 19F MRI.…”
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A Turbo‐Charging System‐Like Contrast Agent for MRI‐Guided STING Pathway‐Activated Cancer Immunotherapy
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Iron Oxide Nanoparticle-Based T<sub>1</sub> Contrast Agents for Magnetic Resonance Imaging: A Review
Published 2024-12-01“…It consolidates findings from multiple studies, discussing current T<sub>1</sub> contrast agents (CAs), the synthesis techniques for IONPs, the theoretical principles for designing IONP-based MRI CAs, and the key factors that impact their T<sub>1</sub> contrast efficacy, such as nanoparticle size, morphology, surface modifications, valence states, and oxygen vacancies. …”
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Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common Cold
Published 2013-01-01“…This was done before Levi-Montalcini’s clarification of PEA’s mechanism of action, analyzing the role of PEA as an anti-inflammatory agent. We will review in depth these studies, as the results support the effectiveness and safety of PEA in flu and respiratory infections.…”
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Establishment and validation of HPLC methods for the determination of folic acid and parabens antimicrobial agents on folic acid oral solution
Published 2025-01-01“…Both the Chinese Pharmacopoeia and the United States Pharmacopoeia use high performance liquid chromatography for the determination of folic acid, but the quantitative methods of parabens are different. …”
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The use of agencies by the Ministry of Internal Affairs of the Ukrainian SSR to control academic historical science in Soviet Ukraine (1953)
Published 2022-06-01“…Through the agent, who worked in this structure, state security officials tried to influence the personnel of the Institute and the main areas of its scientific activity. …”
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Altruistic aging: The evolutionary dynamics balancing longevity and evolvability
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Biostimulants with glycine betaine or kelp extract alleviate heat stress in red raspberry (Rubus idaeus)
Published 2025-01-01Get full text
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