Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients by Suzanne Samarani, Patrick Sagala, Prevost Jantchou, Guy Grimard, Christophe Faure, Colette Deslandres, Devendra K. Amre, Ali Ahmad

“…We investigated activation status, cytotoxic potential, and gut homing ability of the peripheral blood Natural Killer (NK) cells in Crohn disease (CD) patients. …”
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Risk Factors Predicting Recurrent Small Intestinal Resection for Crohn’s Disease of the Terminal Ileum by Hanna Binder, Hugh J Freeman

“…Univariate and multivariate analyses of multiple demographic, clinical, laboratory and pathological variables revealed two apparent statistically significant independent risk factors for a second intestinal resection: steroid treatment, likely an indirect indication of more severe disease activity; and the presence of an internal fistula, consistent with the emerging concept of a relatively more aggressive clinical form of Crohn’s disease.…”
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Short-Term Efficacy of Exclusive Enteral Nutrition in Pediatric Crohn’s Disease: Practice in China by Youyou Luo, Jindan Yu, Hong Zhao, Jingan Lou, Feibo Chen, Kerong Peng, Jie Chen

“…Patients who were followed up for more than 2 months with mild to moderate disease were included. Basic demographics, history, physical examination, the pediatric Crohn disease activity index (PCDAI), laboratory findings, endoscopic findings, and adverse effects were recorded. …”
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Assessment of Serum Dynamic Thiol/Disulfide Homeostasis and Oxidative/Nitrosative Stress in Patients with Crohn’s Disease by Ancel Aysun Bağdaş, Sezgin Barutçu, Ahmet Saracaloğlu, Abdullah Tuncay Demiryürek

“…Background/Aims: Crohn’s disease (CD) is a major subtype of chronic relapsing inflammatory gastrointestinal disorders. …”
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Diagnostic and Clinical Significance of Serum Levels of D-Lactate and Diamine Oxidase in Patients with Crohn’s Disease by Jierui Cai, Hong Chen, Meiling Weng, Shuyu Jiang, Jie Gao

“…Background. Crohn’s disease (CD) is a chronic intestinal inflammatory disease. …”
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Funding the New Biologics – CCOHTA Report on the Cost Effectiveness of Infliximab for Crohn’s Disease: Pearls and Pitfalls by John K Marshall

“…Because the analysis was performed from the perspective of a Canadian provincial ministry of health, only direct medical costs were considered. Patients with active Crohn’s disease are likely to incur significant indirect costs, which could be mitigated by this medication. …”
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Magnetic Resonance Imaging of the Small Bowel in Crohn’s Disease: A Systematic Review and Meta-Analysis by Osman Ahmed, David Mario Rodrigues, Geoffrey C. Nguyen

“…MR imaging provides a reliable alternative in detecting small bowel activity in patients with Crohn’s disease. Its advantages include high diagnostic accuracy and no radiation exposure while its disadvantages include high cost and limited availability.…”
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The simplified GLIM criteria for assessment of malnutrition and its correlation with clinical outcomes in Crohn’s disease patients by Xiaomei Song, Xiaomei Song, Xiaomei Song, Xiaoxin Zhou, Xiaoxin Zhou, Hao Wang, Hong Guo, Jian Yang, Jian Yang

“…The malnourished group had significantly higher Crohn’s Disease Activity Index (CDAI) scores compared to the non-malnourished group (p < 0.001). …”
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Biological markers of disease activity in inflammatory bowel diseases by Edyta Szymanska, Sylwia Szymanska, Maciej Dadalski, Jaroslaw Kierkus

“…However, fast, reliable, and non-invasive biological markers have been used for years for diagnosis as well as for disease activity monitoring. Currently, commonly used faecal calprotectin is the only biomarker approved and recommended by the European Crohn’s and Colitis Organization (ECCO). …”
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Biologic Agents in Crohn’s Patients Reduce CD4+ T Cells Activation and Are Inversely Related to Treg Cells by Eliane Aparecida Rosseto-Welter, Leticia D’argenio-Garcia, Filipa Blasco Tavares Pereira Lopes, Ana Eduarda Zulim Carvalho, Fernando Flaquer, Vanessa Severo-Lemos, Claudia Concer Viero Nora, Flavio Steinwurz, Lucas Pires Garcia Oliveria, Thiago Aloia, Luiz Vicente Rizzo, Cristóvão Luis Pitangueira Mangueira, Karina Inacio Carvalho

“…Crohn’s disease (CD) is a chronic inflammatory disease with a complex interface of broad factors. …”
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Up-to-date overview of imaging techniques in the diagnosis and management of inflammatory bowel diseases by Katarzyna B. Biernacka, Dobromiła Barańska, Piotr Grzelak, Elżbieta Czkwianianc, Katarzyna Szabelska-Zakrzewska

“…Radiological examination occupies a significant role, complementary to endoscopic studies, in the diagnostic process of inflammatory bowel disease (IBD). Both ulcerative colitis and Crohn’s disease, due to multiple remissions and relapses, require repetitive examinations to evaluate the disease extent, severity, and response to pharmacological treatment. …”
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Role of autophagy defects and significance of adherent-invasive <i>Escherichia coli</i> in Crohn's disease development by I. V. Mayev, D. N. Andreev, D. V. Rakitina, Yu. P. Baykova

“…To present new data on a role of molecular genetic disorders of innate immunity at Crohn's disease (CD), and to demonstrate the role of adherent-invasive Escherichia coli (AIEC) as the microorganisms potentially involved in CD development.Summary. …”
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Serum Levels of Lipopolysaccharide and 1,3-β-D-Glucan Refer to the Severity in Patients with Crohn’s Disease by Yanmin Guo, Guangxi Zhou, Chong He, Wenjing Yang, Zhenkun He, Zhanju Liu

“…Interactions between the host and gut microbial community contribute to the pathogenesis of Crohn’s disease (CD). In this study, we aimed to detect lipopolysaccharide (LPS) and 1,3-β-D-glucan (BG) in the sera of CD patients and clarify the potential role in the diagnosis and therapeutic approaches. …”
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Comparative analysis of enteroscopy, computed tomography enterography, and intestinal ultrasound for the evaluation of small bowel Crohn’s disease by Bo Peng, Zhongcheng Liu, Zicheng Huang, Huixian Lin, Zhiyue Wang, Qin Guo

“…Background: The comparable evaluation of computed tomography enterography (CTE), enteroscopy, and intestinal ultrasound in small bowel Crohn’s disease (CD) is imprecise. Objectives: The purpose of this study was to analyze the findings of enteroscopy, CTE, and intestinal ultrasound to determine the advantages and disadvantages of each method for the evaluation of small bowel CD. …”
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Responsiveness and clinical utility of PROMIS instruments in pediatric Crohn's disease: insights from a longitudinal study by Sara Azevedo, Sara Azevedo, Maria Miguel Oliveira, Maria Miguel Oliveira, Paulo Nogueira, Paulo Nogueira, Paulo Nogueira, Ana Isabel Lopes, Ana Isabel Lopes

“…PROMIS pediatric measures assessed PROs. Disease activity was evaluated using the pediatric Crohn's disease activity index (PCDAI) and clinical markers. …”
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Antitumor Necrosis Factor-Alpha (TNF-α) Infliximab-Induced Pleural Effusion and Pericarditis in Crohn’s Disease by Ashley Fonseca, Julee Sunny, Lina M. Felipez

“…Crohn’s disease (CD) is a chronic inflammatory disease that can be associated with intestinal and extraintestinal manifestations. …”
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Outcomes of Pediatric Patients with Crohn’s Disease Received Infliximab or Exclusive Enteral Nutrition during Induction Remission by Yao Lv, Yue Lou, Gan Yang, Youyou Luo, Jingan Lou, Qi Cheng, Jindan Yu, Youhong Fang, Hong Zhao, Kerong Peng, Jie Chen

“…Medical records of newly diagnosed, therapy naïve pediatric patients with CD received with IFX or EEN as induction therapy were retrospectively enrolled. Pediatric Crohn’s disease activity index (PCDAI), Crohn’s disease endoscopic index of severity (CDEIS), and other clinical data were compared pre- and postinduction therapy in two groups. …”
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Inflammatory Bowel Disease and Statins by V. V. Genkel, I. I. Shaposhnik

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The use of oral topically acting glucocorticosteroids in the treatment of inflammatory bowel disease by P. Rutgeerts

“…Glucocorticosteroids are the mainstay of treatment of active Crohn's disease and ulcerative colitis. These drugs however carry important cosmetic short-term side effects and when used long-term they induce severe irreversible complications. …”
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Immune Thrombocytopenic Purpura (ITP) as an Uncommon Extraintestinal Complication of Crohn’s Disease: Case Vignette and Systematic Literature Review by Raisa Epistola, Tiffanie Do, Ritika Vankina, Daniel Wu, James Yeh, Michael W. Fleischman, Jennifer M. Lee

“…While the association of immune thrombocytopenic purpura (ITP) and inflammatory bowel disease (IBD) has been described in a few case reports, management of ITP as an extraintestinal manifestation of Crohn’s disease (CD) is less studied. …”
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