Combination Ciprofloxacin and Metronidazole for Active Crohn’s Disease by Susan L Greenbloom, A Hillary Steinhart, Gordon R Greenberg

“…Recent experimental evidence underscores the contribution of intestinal bacteria to the inflammatory process of Crohn's disease. This open study examined the efficacy and safety of combination ciprofloxacin and metronidazole for patients with active Crohn's disease of the ileum and/or colon. …”
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Impact of Disease Activity on the Quality of Life of Crohn’s Disease Patients by T Michael Vallis, Geoffrey K Turnbull

“…Crohn’s disease (CD) patients often suffer severe symptoms that impair their quality of life. …”
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The Crohn’s Disease Activity Index, Its Derivatives and the Inflammatory Bowel Disease Questionnaire: A Review of Instruments to Assess in Crohn’s Disease by Eric M Yoshida

“…The Crohn’s Disease Activity Index (CDAI) has been used to measure Crohn’s activity for over a quarter of a century. …”
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Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity by Jingyun Cheng, Hui Xie, Hao Yang, Ke Wang, Guobin Xu, Guangyao Wu

“…To explore the feasibility of computed tomography enterography (CTE) in the quantitative evaluation of the activity of Crohn’s disease (CD). Methods. There were 49 CD patients with whole clinical, enteroscopy, and CTE data to be analyzed retrospectively. …”
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Assessment of the usefulness of imaging studies and biomarkers in the activity of Crohn’s disease by Grażyna Piotrowicz, Agnieszka Klufczyńska, Piotr Banaszkiewicz, Łukasz Dorosz, Grażyna Rydzewska

Subjects: “…crohn’s disease activity index…”
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Oral 5-Aminosalicyclic Acid Versus 6-Methylprednisolone in Active Crohn's Disease by Jürgen Schölmerich, Harro Jenss, Franz Hartmann, Hanne Döpfer, The German 5-ASA Study Group

“…The response to 5-aminosalicylic acid (5-ASA) in active Crohn's disease was studied in comparison to methylprednisolone in a 24 week randomized double-blind multicentre study. …”
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3D-EAUS and MRI in the Activity of Anal Fistulas in Crohn’s Disease by Maria Eleonora Alabiso, Francesca Iasiello, Gianluca Pellino, Aniello Iacomino, Luca Roberto, Antonio Pinto, Gabriele Riegler, Francesco Selvaggi, Alfonso Reginelli

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The Role of MR Enterography in Assessing Crohn’s Disease Activity and Treatment Response by Matthew P. Moy, Jenny Sauk, Michael S. Gee

“…MR enterography (MRE) has become the primary imaging modality in the assessment of Crohn’s disease (CD) in both children and adults at many institutions in the United States and worldwide, primarily due to its noninvasiveness, superior soft tissue contrast, and lack of ionizing radiation. …”
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Corrigendum to “Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity” by Jingyun Cheng, Hui Xie, Hao Yang, Ke Wang, Guobin Xu, Guangyao Wu

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The effects of hyperbaric treatment on perianal fistula activity in patients with Crohn’s disease by Grażyna Piotrowicz, Jacek Kot, Andrzej Babicki, Piotr Banaszkiewicz, Adam Piotrowicz, Magdalena Rzeszutek, Agata Rudnik, Piotr Zientara, Joanna Adamska-Mieruszewska, Grażyna Rydzewska

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Open Trial of Cyclosporine in Patients with Severe Active Crohn's Disease Refractory to Conventional Therapy by Kevork M. Peltekian, C. Noel Williams, Allan S. MacDonald, Peter D. Roy, Elizabeth Czolpinska

“…T he remaining 10 patients all improved within four weeks as measured by three different clinical indices: Crohn's Disease Activity Index, Simple Index of Crohn's Disease Activity and Mean Score of Therapeutic Goals (MSTG). …”
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The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease by Paulina Jakubczyk, Piotr Widera, Justyna Helis, Maciej Michalik, Aleksandra Buczek, Hubert Bigajski, Aleksandra Banaś, Olga Bilczewska, Wiktoria Janik, Marta Handschuh

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Nutrition and Crohn's Disease: An Overview by C Ó'Moráin

“…Elemental diets contain glutamine and arginine, which have a direct effect on intestinal mucosa and improve immune function. Patients with active Crohn's disease have increased intestinal permeability; treatment with an elemental diet improves the permeability defect.…”
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Role of Cyclosporine in Crohn's Disease by CN Williams

“…A prospective, placebo controlled, international trial of cyclosporine A in patients with steroid-resistant Crohn's disease was recently published. All patients in this study had active Crohn's disease (Crohn's disease activity index greater than 150). …”
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Biologics in Paediatric Crohn's Disease by Oliver Gouldthorpe, Anthony G. Catto-Smith, George Alex

“…Crohn's disease affects increasing numbers of children worldwide. …”
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Ileocaecal Intussusception with a Lead Point: Unusual MDCT Findings of Active Crohn’s Disease Involving the Appendix by Ebru Ozan, Gokce Kaan Atac, Egemen Akincioglu, Mete Keskin, Kamil Gulpinar

“…Unlike intussusceptions in children, which are idiopathic in 90% of cases, adult intussusceptions have an identifiable cause (lead point) in the majority of cases. Crohn’s disease (CD) may affect any part of the gastrointestinal tract, including the appendix. …”
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A review of magnetic resonance enterography based Crohn’s disease activity indices in paediatric patients by Roma B. Herman, Paulina Dumnicka, Krzysztof Fyderek

“…Magnetic resonance enterography (MRE) is a commonly used method for non-invasive diagnosing and following of inflammatory bowel disease (IBD). Numerous reviews that compare and discuss MRE-based Crohn’s disease (CD) activity indices for adults have been published; however, no reviews of this kind have been published for children. …”
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Interrelationships of the Intestinal Microbiome, Trimethylamine N-Oxide and Lipopolysaccharide-Binding Protein with Crohn’s Disease Activity by Yelena Laryushina, Nadezhda Samoilova-Bedych, Lyudmila Turgunova, Alexandr Marchenko, Yermek Turgunov, Samat Kozhakhmetov, Maxat Suieubayev, Nurislam Mukhanbetzhanov, Nadezhda Kabdulina

“…Crohn’s disease (CD) is a multifactorial inflammatory bowel disease whose pathogenetic mechanisms are a field of ongoing study. …”
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Budesonide in the Management of Patients with Crohn’s Disease by ABR Thomson, Daniel Sadowski, Robert Jenkins, Gary Wild

“…The evidence presented here is that budesonide (Entocort, Astra Pharma) 9 mg/day is superior to placebo and equivalent to systemically active glucocorticosteroids in achieving disease remission in patients with active Crohn's disease, and in prolonging the recurrence time of symptomatic disease. …”
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Laparoscopic Surgery for Recurrent Crohn's Disease by Antonino Spinelli, Matteo Sacchi, Piero Bazzi, Nicoletta Leone, Silvio Danese, Marco Montorsi

“…In spite of the recent improvements in drug therapy, surgery still represents the most frequent treatment for Crohn's disease (CD) complications. Laparoscopy has been widely applied over the last twenty years in colorectal surgery and was associated with lower postoperative pain, shorter hospitalization, faster return to daily activities, and better cosmetic results. …”
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