-
21
-
22
Rosiglitazone, a Ligand to PPARγ, Improves Blood Pressure and Vascular Function through Renin-Angiotensin System Regulation
Published 2019-01-01“…In this work, we hypothesized that RGZ exerts a PPARγ–dependent regulation of blood pressure through modulation of angiotensin-converting enzyme (ACE)-type 2 (ACE2)/angiotensin-(1-7)/angiotensin II type-2 receptor (AT2R) axis in an experimental model of high blood pressure. …”
Get full text
Article -
23
-
24
Renin–angiotensin–aldosterone system activation in plasma as marker for prognosis in critically ill patients with COVID-19: a prospective exploratory study
Published 2025-01-01“…After seven days in the ICU, Ang I, Ang II, Ang III and Ang IV concentrations decreased, while ACE and ACE2 levels increased. …”
Get full text
Article -
25
-
26
Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms
Published 2025-02-01“…While live-attenuated vaccines are a highly effective modality, they pose a risk of adverse effects, including virulence reversion. …”
Get full text
Article -
27
-
28
Different lysine-to-methionine ratios in a low-protein diet affect the microbiome and metabolome, influencing the jejunal barrier function in Tibetan sheep
Published 2025-02-01“…The feeding trial lasted 100 days, including a 10-day acclimation period and a 90-day experimental period.ResultsThe hematoxylin–eosin (H&E) sections showed that the LP-L group had a significantly increased villus height compared to the LP-M and LP-H groups (p < 0.05). …”
Get full text
Article -
29
-
30
-
31
Adherence to guidelines for creatinine and potassium monitoring and discontinuation following renin–angiotensin system blockade: a UK general practice-based cohort study
Published 2017-01-01“…Objectives To examine adherence to serum creatinine and potassium monitoring and discontinuation guidelines following initiation of treatment with ACE inhibitors (ACEI) or angiotensin receptor blockers (ARBs); and whether high-risk patients are monitored.Design A general practice-based cohort study using electronic health records from the UK Clinical Practice Research Datalink and Hospital Episode Statistics.Setting UK primary care, 2004–2014.Subjects 223 814 new ACEI/ARB users.Main outcome measures Proportion of patients with renal function monitoring before and after ACEI/ARB initiation; creatinine increase ≥30% or potassium levels >6 mmol/L at first follow-up monitoring; and treatment discontinuation after such changes. …”
Get full text
Article -
32
-
33
Antineutrophil Cytoplasmic Antibody Vasculitis after Coronary Artery Bypass Grafting
Published 2024-01-01Get full text
Article -
34
Silent Spontaneous Uterine Rupture at 36 Weeks of Gestation
Published 2015-01-01Get full text
Article -
35
-
36
-
37
Investigating the impact of Multiwalled Carbon Nanotubes exposure on enzymatic activities and histopathological variations in Swiss albino mice
Published 2025-01-01“…Hematoxylin and Eosin (H&E) staining of tissue samples was done along with a histopathological examination. During a 14-day exposure, ACE, NADPH Oxidase, ALT, and AST enzyme levels were significantly higher in the exposed groups (0.45 µg and 0.90 µg) than in the control group (p < 0.05). …”
Get full text
Article -
38
-
39
Effect of Allium cepa L. on Lipopolysaccharide-Stimulated Osteoclast Precursor Cell Viability, Count, and Morphology Using 4′,6-Diamidino-2-phenylindole-Staining
Published 2014-01-01“…Osteoclast precursor cells (RAW 264.7) were stimulated by Pg LPS (1 μg/mL) and E. coli LPS (1 μg/mL) in the presence or absence of different concentrations of AcE (10–1000 μg/mL) for 5 days at 37°C/5% CO2. Resazurin reduction and total protein content assays were used to detect cell viability. …”
Get full text
Article -
40
Negative effects of adverse childhood experiences and absence of positive childhood experiences on healthcare employees: survey findings built on 10 years of trauma-informed develo...
Published 2025-01-01“…This study sought to describe the prevalence of Adverse Childhood Experiences (ACEs) and Positive Childhood Experiences (PCEs) and their association with present-day workplace and wellbeing outcomes among a sample of healthcare teammates overall, as well as specifically among nurses. …”
Get full text
Article