Showing 421 - 440 results of 801 for search 'abiogenesis~', query time: 3.69s Refine Results
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    Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq by Nicholas M. Forino, Jia Zheng Woo, Arthur J. Zaug, Arcelia Gonzalez Jimenez, Eva Edelson, Thomas R. Cech, Silvi Rouskin, Michael D. Stone

    Published 2025-01-01
    “…Abstract Biogenesis of human telomerase requires its RNA subunit (hTR) to fold into a multi-domain architecture that includes the template-pseudoknot (t/PK) and the three-way junction (CR4/5). …”
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  8. 428

    Relationship between Dyskerin Expression and Telomerase Activity in Human Breast Cancer by Lorenzo Montanaro, Maria Calienni, Claudio Ceccarelli, Donatella Santini, Mario Taffurelli, Stefano Pileri, Davide Treré, Massimo Derenzini

    Published 2008-01-01
    “…In conclusion, our results indicated that, beside its effect on ribosome biogenesis, the levels of dyskerin in cancer cells modulate telomerase activity through the regulation of TERC levels, independently of TERT expression. …”
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  9. 429

    Intracellular Membrane Contact Sites in Skeletal Muscle Cells by Matteo Serano, Stefano Perni, Enrico Pierantozzi, Annunziatina Laurino, Vincenzo Sorrentino, Daniela Rossi

    Published 2025-01-01
    “…This review explores the key processes in biogenesis and assembly of intracellular membrane contact sites as well as the membrane remodeling that occurs in response to muscle fatigue.…”
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  10. 430

    PfFBXO1 is essential for inner membrane complex formation in Plasmodium falciparum during both asexual and transmission stages by Sreelakshmi K. Sreenivasamurthy, Carlos Gustavo Baptista, Christopher M. West, Ira J. Blader, Jeffrey D. Dvorin

    Published 2025-02-01
    “…We hypothesize that PfFBXO1 is necessary for IMC biogenesis, chromosomal maintenance, vesicular transport, and ubiquitin-mediated translational regulation of proteins in both sexual and asexual stages of P. falciparum.…”
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  11. 431

    Expression Pattern of a Homeotic Gene, HOXA5, in Normal Breast and in Breast Tumors by Gregory S. Henderson, Paul J. van Diest, Horst Burger, Jose Russo, Venu Raman

    Published 2006-01-01
    “…Introduction: Homeotic (HOX) gene products are now known to be functionally associated with breast cancer biogenesis. Recent evidence has indicated that HOXA5 regulates both p53 and progesterone receptor expression levels in breast cancer cells. …”
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  12. 432

    A Phage‐Based Approach to Identify Antivirulence Inhibitors of Bacterial Type IV Pili by Tori M. Shimozono, Nancy J. Vogelaar, Megan T. O'Hara, Zhaomin Yang

    Published 2025-01-01
    “…The bacterial type IV pilus (T4P), an extracellular protein filament that depends on the T4P machinery (T4PM) for its biogenesis, dynamics and function, is a key virulence factor in many significant bacterial pathogens. …”
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  13. 433

    Role of Epigenetics in Modulating Phenotypic Plasticity against Abiotic Stresses in Plants by Fayaz Ahmad Dar, Naveed Ul Mushtaq, Seerat Saleem, Reiaz Ul Rehman, Tanvir Ul Hassan Dar, Khalid Rehman Hakeem

    Published 2022-01-01
    “…By the induction and modulation of various cellular processes like DNA methylation, histone modification, and biogenesis of noncoding RNAs, the plant genome can be activated which can help in achieving a quicker response against various plant stresses. …”
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  14. 434

    Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in Mucopolysaccharidosis VII by Nishan Mandal, Apurba Das, Rupak Datta

    Published 2025-03-01
    “…We found that both autophagosome biogenesis and lysosome-mediated autophagosomal turnover were impaired in the CG2135−/− fly brain. …”
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  15. 435

    Identification of Signal Pathways and Hub Genes of Pulmonary Arterial Hypertension by Bioinformatic Analysis by Rui-Qi Wei, Wen-Mei Zhang, Zhe Liang, Chunmei Piao, Guangfa Zhu

    Published 2022-01-01
    “…Significant KEGG pathway enrichment included ribosome biogenesis in eukaryotes, RNA transport, proteoglycans in cancer, dilated cardiomyopathy, rheumatoid arthritis, vascular smooth muscle contraction, focal adhesion, regulation of the actin cytoskeleton, and hypertrophic cardiomyopathy. …”
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  16. 436

    Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria by Jinyun Chen, Qian Wang, Xuebing Feng, Zhuoya Zhang, Linyu Geng, Ting Xu, Dandan Wang, Lingyun Sun

    Published 2016-01-01
    “…Umbilical cord-derived mesenchymal stem cells (UC-MSCs) could inhibit respiratory mitochondrial biogenesis in activated T cells to downregulate autophagy and consequently decrease T cell apoptosis through mitochondrial transfer and thus may play an important role in SLE treatment.…”
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  17. 437

    Peculiarities of the molecular composition of heterochromatin associated with pronucleoli in mouse embryos by I. O. Bogolyubova, Z. K. Sailau, D. S. Bogolyubov

    Published 2019-03-01
    “…In zygotes, some factors of mRNA biogenesis including splicing factor SC35 (SRSF2) and basal transcription factor TFIID are detectable in the ring chromatin. …”
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  18. 438

    A Comparative Study on Growth Performance, Body Composition, and Liver Tissue Metabolism Rearing on Soybean Lecithin-Enriched Artemia Nauplii and Microdiet in Rock Bream (Oplegnath... by Pian Zhang, Peng Tan, Lei Zhang, Wenliang Zhu, Ruiyi Chen, Ligai Wang, Dongdong Xu

    Published 2023-01-01
    “…Notably, feeding with MD significantly increased ribosome biogenesis-related genes as well as mitochondria synthesis-related gene expression, indicating a high protein anabolism rate and high energy production in liver tissue. …”
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  19. 439

    In vivo Study of the Histone Chaperone Activity of Nucleolin by FRAP by Xavier Gaume, Karine Monier, Françoise Argoul, Fabien Mongelard, Philippe Bouvet

    Published 2011-01-01
    “…Nucleolin is a major nucleolar protein involved in various aspects of ribosome biogenesis such as regulation of polymerase I transcription, pre-RNA maturation, and ribosome assembly. …”
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  20. 440

    Upregulation of PGC-1α Attenuates Oxygen-Glucose Deprivation-Induced Hippocampal Neuronal Injury by Bin Han, Hui Zhao, Xingji Gong, Jinping Sun, Song Chi, Tao Liu, Anmu Xie

    Published 2022-01-01
    “…PPARγ coactivator-1α (PGC-1α) is a master regulator of mitochondrial biogenesis. However, the role and the precise mechanism of how PGC-1α alleviates hippocampal neuronal injury remain unknown. …”
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