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A Review of Antibiotic Efficacy in COVID-19 Control
Published 2023-01-01“…Numerous studies have shown that mitochondria, as the center of cell biogenesis, are vulnerable to drugs, especially antibiotics. …”
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A mutation in RNA polymerase imparts resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism
Published 2025-02-01“…The CEF-resistant rpoC G1122D mutant evades these metabolic perturbations, and repression of the BCAA and pyrimidine pathways may function to restrict membrane biogenesis, which is beneficial when cell wall synthesis is impaired. …”
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Yeast Methylotrophy: Metabolism, Gene Regulation and Peroxisome Homeostasis
Published 2011-01-01“…These features have made methylotrophic yeasts attractive hosts for the production of heterologous proteins and useful model organisms for the study of peroxisome biogenesis and degradation. In this paper, we describe recent insights into the molecular basis of yeast methylotrophy.…”
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Impacts of Hyaluronan on Extracellular Vesicle Production and Signaling
Published 2025-01-01“…The goal of this review is to present a comprehensive summary of the research on HA and its related receptors and enzymes in extracellular vesicle biogenesis and the cellular responses to vesicles bearing these extracellular matrix modulators. …”
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Does Adiponectin Act as an Antiangiogenic Factor in B-Cell Chronic Lymphocytic Leukemia?
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The role of Nrf2 transcription factors in various physiological and pathological states
Published 2024-07-01“…Initially recognized for its role in cellular response to oxidative stress, Nrf2 is now known to be involved in a variety of regulatory process, including metabolic regulation, autophagy, protein homeostasis (proteostasis), and mitochondrial biogenesis. The expression of Nrf2 target genes is highly dependent on stimulus activation and interactions with transcription factors, activators, and repressors. …”
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Protein Machineries Involved in the Attachment of Heme to Cytochrome c: Protein Structures and Molecular Mechanisms
Published 2013-01-01“…This posttranslational process, known as Cyt c biogenesis or Cyt c maturation, ensures the stereospecific formation of the thioether bonds between the heme vinyl groups and the cysteine thiols of the apoCyt heme binding motif. …”
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Emerging role of exosomes in cancer therapy: progress and challenges
Published 2025-01-01“…Abstract This review highlights recent progress in exosome-based drug delivery for cancer therapy, covering exosome biogenesis, cargo selection mechanisms, and their application across multiple cancer types. …”
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The Mitochondrial Aminoacyl tRNA Synthetases: Genes and Syndromes
Published 2014-01-01“…This is because protein components of the RC are encoded by both mitochondrial and nuclear genomes and are essential in all cells. In addition, the biogenesis and maintenance of mitochondria, including mitochondrial DNA (mtDNA) replication, transcription, and translation, require nuclear-encoded genes. …”
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Biology of extracellular vesicles and the potential of tumor-derived vesicles for subverting immunotherapy of cancer
Published 2025-01-01“…EVs are heterogeneous in size, biogenesis, molecular/genetic content and functions. …”
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Signal Transduction of Sphingosine-1-Phosphate G Protein—Coupled Receptors
Published 2006-01-01Get full text
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TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles
Published 2025-02-01“…Nevertheless, whether TGF-β signaling coordinates EV biogenesis is a relevant topic that remains minimally explored. …”
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