甲基转移酶3对人脑血管平滑肌细胞基因表达及增殖和迁移功能的影响 Effects of Methyltransferase 3 on Gene Expression, Proliferation, and Migration Functions of Human Brain Vascular Smooth Muscle Cells... by 孟晨曦1，孙洪英2，张佳2，毛戬2，杨阳3，策乐木格3 (MENG Chenxi1, SUN Hongying2, ZHANG Jia2, MAO Jian2, YANG Yang3, Celemuge3 )

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The First Infant Bloodstream Infection Caused by Pantoea dispersa in China: A Case Report and Literature Review by Yu W, Sun Z, Wang M, Li Z, Zhang C, Sun Y, Wang S

“…Wenwen Yu,1,2 Zhaohui Sun,3 Mengyuan Wang,1,2 Zheng Li,1,2 Chunyan Zhang,1,2 Yanmeng Sun,1,2 Shifu Wang1,2 1Department of Clinical Microbiology, Children’s Hospital Affiliated to Shandong University, Jinan Children’s Hospital, Jinan, 250022, People’s Republic of China; 2Shandong Provincial Clinical Research Center for Children’s Health and Disease, Jinan, 250022, People’s Republic of China; 3Department of Ultrasound, Zhaoyuan People’s Hospital, Yantai, People’s Republic of ChinaCorrespondence: Shifu Wang, Email wshfu709@163.comAbstract: Pantoea is a prevalent environmental Gram-negative bacterium comprising over 20 distinct species. …”
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Synergistic Effects of FGF-18 and TGF-β3 on the Chondrogenesis of Human Adipose-Derived Mesenchymal Stem Cells in the Pellet Culture by Liangjie Huang, Lingxian Yi, Chunli Zhang, Ying He, Liangliang Zhou, Yan Liu, Long Qian, Shuxun Hou, Tujun Weng

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Forest Fire Clustering: A Novel Tool for Identifying Star Members of Clusters by Xingyin Wei, Jing Chen, Su Zhang, Feilong He, Yunbo Zhao, Xuran He, Yongjie Fang, Xinhao Chen, Hao Yang

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White Matter Injury in Central Nervous System Disorders by Zheng L, Wang X, Li P, Hao Y, Zhang H, Chen H, Zheng Z

“…Ling Zheng, Xiaoyu Wang, Peng Li, Yuwen Hao, Hao Zhang, Haoyue Chen, Zuncheng Zheng Department of Rehabilitation Medicine, The Affiliated Taian City Central Hospital of Qingdao University, Taian, 271000, People’s Republic of ChinaCorrespondence: Zuncheng Zheng, Email zhengzc1965@126.comAbstract: As the aging process accelerates and living conditions improve, central nervous system (CNS) diseases have become a major public health problem. …”
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Effects of Food on the Pharmacokinetics and Safety of HA121-28 Tablet, a Novel Multi-Targeting Tyrosine Kinase Inhibitor, in Healthy Chinese Subjects: A Phase I Clinical Trial by Liu Y, Li X, Zhang M, Men Y, Wang Y, Zhu X, Zheng L

“…Yixian Liu,1,2,* Xiaoyu Li,1,2,* Mengyu Zhang,1,2 Yuchun Men,1,2 Ying Wang,1,2 Xiaohong Zhu,1,2 Li Zheng1,2 1Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China; 2Clinical Trial Center, NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li Zheng, Cancer Center, West China Hospital, Sichuan University, No. 5 Telecom Road, Wuhou District, Chengdu, 610041, People’s Republic of China, Email zhengli@wchscu.cnPurpose: HA121-28, a novel multi-targeting tyrosine kinase inhibitor, has dual efficacy against tumor growth and neovascularization. …”
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Design of pH-Responsive Nanomaterials Based on the Tumor Microenvironment by Liu Y, Si L, Jiang Y, Jiang S, Zhang X, Li S, Chen J, Hu J

“…Yunheng Liu,1,* Longqing Si,1,* Yuxuan Jiang,1,* Shaojing Jiang,2 Xiaokang Zhang,1 Song Li,1 Jing Chen,1 Jinghui Hu2 1School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China; 2Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Chen, School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email chenjingbyyxy@163.com Jinghui Hu, Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email bykfhjh@163.comAbstract: The metabolic activity of tumor cells leads to the acidification of the surrounding microenvironment, which provides new strategies for the application of nanotechnology in cancer therapy. …”
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A Nomogram Based on Laboratory Data, Inflammatory Bowel Disease Questionnaire and CT Enterography for Activity Evaluation in Crohn’s Disease by Zhang H, Shen Y, Cao B, Zheng X, Zhao D, Hu J, Wu X

“…Han Zhang,1,* Yi Shen,1,* Bo Cao,2 Xiaomin Zheng,1 Dehan Zhao,3 Jing Hu,4 Xingwang Wu1 1Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China; 2Department of Radiology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, People’s Republic of China; 3Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, Anhui, 230022, People’s Republic of China; 4Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Hu, The First Affiliated Hospital of Anhui Medical University, Department of Gastroenterology, Hefei, Anhui, 230022, People’s Republic of China, Tel +86 139-5510-7753, Email hujing810@163.com Xingwang Wu, The First Affiliated Hospital of Anhui Medical University, Department of Radiology, Hefei, Anhui, 230022, People’s Republic of China, Tel +86 153-7533-0696, Email duobi2004@126.comBackground: Accurately assessing the activity of Crohn’s disease (CD) is crucial for determining prognosis and guiding treatment strategies for CD patients.Objective: This study aimed to develop and validate a nomogram for assessing CD activity.Methods: The semi-automatic segmentation method and PyRadiomics software were employed to segment and extract radiomics features from the spectral CT enterography images of lesions in 107 CD patients. …”
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GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia by Lai L, Wu H, Peng L, Zhang Z, Wu X, Zheng S, Su Z, Chu H

“…Lingzhi Lai,1 Hao Wu,1 Liang Peng,2 Zhen Zhang,3 Xinfan Wu,1 Shuo Zheng,3 Zekang Su,3 Hongxing Chu3 1Maoming People’s Hospital, Maoming, Guangdong, People’s Republic of China; 2The First People’s Hospital of Guiyang, Guiyang, Guizhou, People’s Republic of China; 3Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong, People’s Republic of ChinaCorrespondence: Hongxing Chu, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, People’s Republic of China, Tel +86-13533856675, Email chuhongxing22@smu.edu.cnPurpose: Limb ischemia is a refractory disease characterized by insufficient angiogenesis and tissue necrosis. …”
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Silent magnetic resonance angiography diagnostic value of intracranial unruptured aneurysms by Bin Lv, Tingyang Zhang, Ning Wang, Lu Liu, Mingyu Li, Meng Li, Mingguang Sun, Xiao Zang, Xinfeng Liu, Rongju Zhang, Xiangyu Cao, Zhihua Du, Jun Wang, Jinhao Lyu, Xueyang Wang, Qi Duan, Fangfang Guo, Xin Lou, Chenglin Tian

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Construction and Validation of a Model for Predicting Fear of Childbirth: A Cross-Sectional Population Study via Machine Learning by Zhang ZL, Chen KJ, Chen H, Zhu MM, Gu JJ, Jiang LS, Zheng L, Zhou SG

“…Zhi-Lin Zhang,* Kang-Jia Chen,* Hui Chen,* Miao-Miao Zhu, Jing-Jing Gu, Li-Shuai Jiang, Lan Zheng, Shu-Guang Zhou Department of Gynecology and Obstetrics, Maternal and Child Medical Center of Anhui Medical University, The Fifth Affiliated Clinical College of Anhui Medical University, Anhui Women and Children’s Medical Center, Hefei, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shu-Guang Zhou, Email zhoushuguang@ahmu.edu.cn; Lan Zheng, Email zhenglan2022@163.comBackground: Fear of childbirth (FOC) is a psychological state of fear and distress that pregnant women experience when they approach labor. …”
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Transarterial Chemoembolization Plus Radiofrequency Ablation and Iodine-125 Seed Implantation for Hepatocellular Carcinoma in High-Risk Locations: A Propensity Score-Matched Analys... by Zhang G, Ren Y, Liu J, Cao Y, Xiong F, Liang B, Zheng C, Kan X

“…Guilin Zhang,1– 3,* Yanqiao Ren,1– 3,* Jiayun Liu,1– 3 Yanyan Cao,1– 3 Fu Xiong,1– 3 Bin Liang,1– 3 Chuansheng Zheng,1– 3 Xuefeng Kan1– 3 1Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Hubei Provincial Clinical Research Center for Precision Radiology & Interventional Medicine, Wuhan, 430022, People’s Republic of China; 3Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuefeng Kan; Chuansheng Zheng, Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, Hubei province, 430022, People’s Republic of China, Email xkliulang1314@163.com; hqzcsxh@sina.comBackground & Aims: The effect of transarterial chemoembolization (TACE) plus radiofrequency ablation (RFA) (TACE-RFA) for hepatocellular carcinoma (HCC) in high-risk locations is not satisfactory. …”
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A Rare Q-Fever Infection Diagnosed Using Metagenomic Next-Generation Sequencing in Liver Transplantation Patient: A Case Report and Literature Review by Niu X, Qiu S, Zheng Y, Li L, Tian E, Liu J, Gai W, Zhang Q, Jin H

“…Xinxin Niu,1,* Shuang Qiu,1,* Yafeng Zheng,2,* Li Li,1 Eryun Tian,1 Jie Liu,1 Wei Gai,2 Qing Zhang,1 Hailong Jin1 1Department of Organ Transplantation, The Third Medical Center of Chinese PLA General Hospital, Beijing, People’s Republic of China; 2WillingMed Technology (Beijing) Co., Ltd, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qing Zhang; Hailong Jin, Department of Organ Transplantation, The Third Medical Center of Chinese PLA General Hospital, Beijing, 100039, People’s Republic of China, Email zqy6920@sina.com; jhl309@sina.comAbstract: Q fever is a zoonotic disease caused by the Gram-negative bacterium Coxiella burnetii, typically transmitted through exposure to infected animal secretions. …”
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Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies by Mengdi Zhang, Haiying Qiu, Zheyi Han, Yazhong Ma, Jingjing Hou, Jingwei Yuan, Haiyan Jia, Menglu Zhou, Hongjie Lu, Yan Wu

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Differences in Rhizosphere Microbial Community Structure and Composition in Resistance and Susceptible Wheat to Fusarium Head Blight by Han Li, Mingshuang Tang, Tao Zheng, Ming Yang, Youning Wang, Yating Shuai, Yan Li, Yibo Zhang, Dongfang Ma

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Bioinformatics-Based Exploration of the Ability of Ginkgetin to Alleviate the Senescence of Cardiomyocytes After Myocardial Infarction and Its Cardioprotective Effects by Li H, Wei D, Cao H, Han Y, Li L, Liu Y, Qi J, Wu X, Zhang Z

“…Han Li,1,* Dongsheng Wei,2,* Huimin Cao,2 Yelei Han,1 Luzhen Li,1 Yuting Liu,1 Jiajie Qi,1 Xinyue Wu,1 Zhe Zhang2,3 1The First School of Clinical Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, 110847, People’s Republic of China; 2Key Laboratory of Ministry of Education for TCM Viscera-State Theory and Applications, Liaoning University of Traditional Chinese Medicine, Shenyang, 110847, People’s Republic of China; 3Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, 110032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhe Zhang, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33 Beiling Street, Shenyang, 110032, People’s Republic of China, Tel +86-18102459155, Email pedtrainzhzh7676@163.comPurpose: Myocardial infarction (MI) is a prevalent cardiovascular disorder affecting individuals worldwide. …”
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Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research by Chen H, Fu S, Zhi X, Wang Y, Liu F, Li Y, Ren F, Zhang J, Ren L, Wang Y

“…Hao Chen,1,* Shifang Fu,2,* Xiaoyu Zhi,2 Yu Wang,2 Fanqi Liu,2 Yuetong Li,2 Fengjiao Ren,2 Junfeng Zhang,1,3,4 Longsheng Ren,1 Yanguo Wang2 1Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China; 2Rehabilitation Department, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300250, People’s Republic of China; 3Rehabilitation Center, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, People’s Republic of China; 4National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, 300381, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yanguo Wang, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300250, People’s Republic of China, Email tjwangyanguo@163.comAbstract: Tactile perception is one of the important ways through which humans interact with the external environment. …”
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Comparison of prognosis for T4b rectal cancer with different pelvic compartment involvement treated using neoadjuvant chemoradiotherapy and implications for refinement of the curre... by Yang-zi Zhang, Maxiaowei Song, Shuai Li, Jian Tie, Xiang-gao Zhu, Yong-heng Li, Ai-wen Wu, Yong Cai, Wei-hu Wang

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A Machine Learning Model for Predicting Prognosis in HCC Patients With Diabetes After TACE by Wu L, Chen L, Zhang L, Liu Y, Ouyang D, Wu W, Lei Y, Han P, Zhao H, Zheng C

“…Linxia Wu,1– 3,* Lei Chen,1– 3,* Lijie Zhang,1,4,* Yiming Liu,1,5,* Die Ouyang,1 Wenlong Wu,5,6 Yu Lei,5,6 Ping Han,1 Huangxuan Zhao,1– 3 Chuansheng Zheng1– 3 1Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430022, People’s Republic of China; 2Department of Interventional Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430022, People’s Republic of China; 3Hubei Provincial Clinical Research Center for Precision Radiology & Interventional Medicine, Wuhan, Hubei Province, 430022, People’s Republic of China; 4Department of Interventional Radiology, The Fifth Medical Center of Chinese, PLA General Hospital, Beijing, 100039, People’s Republic of China; 5Department of Interventional Radiology, Auto Valley Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430056, People’s Republic of China; 6Department of Interventional Radiology, Jinyinhu Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430048, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuansheng Zheng; Huangxuan Zhao, Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430022, People’s Republic of China, Email hqzcsxh@sina.com; zhao_huangxuan@sina.comPurpose: Type II diabetes mellitus (T2DM) has been found to increase the mortality of patients with hepatocellular carcinoma (HCC). …”
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Huanglian Ejiao Decoction Alleviates Ulcerative Colitis in Mice Through Regulating the Gut Microbiota and Inhibiting the Ratio of Th1 and Th2 Cells by Tang J, Hu Y, Fang J, Zhu W, Xu W, Yu D, Zheng Z, Zhou Q, Fu H, Zhang W

“…Jingyi Tang,1,2,* Yingnan Hu,1,3,* Jintao Fang,1,* Weihan Zhu,1,* Wenjun Xu,1 Dian Yu,1 Zhipeng Zheng,4 Qiujing Zhou,4 Huiying Fu,4 Wei Zhang1,4 1The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, 310053, People’s Republic of China; 2Lanxi Hospital of Traditional Chinese Medicine, Jinhua, 321100, People’s Republic of China; 3The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510510, People’s Republic of China; 4The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310005, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Zhang; Huiying Fu, Email zhangweils1968@163.com; fhy131@126.comBackground: Huanglian-ejiao decoction (HED) is a Chinese traditional medicinal formula evolved from the Shanghan Lun (Treatise on Febrile Diseases). …”
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