Genetic Polymorphism and Expression of CXCR4 in Breast Cancer by Marina Okuyama Kishima, Karen Brajão de Oliveira, Carolina Batista Ariza, Carlos Eduardo Coral de Oliveira, Roberta Losi Guembarovski, Bruna Karina Banin Hirata, Felipe Campos de Almeida, Glauco Akelinghton Freire Vitiello, Kleber Paiva Trugilo, Alda Fiorina Maria Losi Guembarovski, Walter Jorge Sobrinho, Clodoaldo Zago Campos, Maria Angelica Ehara Watanabe

“…CXCR4 genetic polymorphisms, as well as their expression level, have been associated with cancer development and prognosis. …”
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Integration of Transcriptomics and Metabolomics Provides Insight into the Growth-Promoting Functions of <i>Solanum khasianum</i> Endophyte in <i>Medicago sativa</i> by Jiahui Li, Shijia Zhou, Jiaru Fang, Qihang Cai, Yanbo Yang, Zhenghai Sun, Liping Li, Weiwei Li

“…<i>Alternaria alstroemeriae</i> has often been used as a pathogenic bacterium in previous studies, and studies on the growth-promoting effects of <i>A. alstroemeriae</i> are rare. …”
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Intracardiac Fibrinolysis and Endothelium Activation Related to Atrial Fibrillation Ablation with Different Techniques by Orsolya Hajas, Zsuzsa Bagoly, Noémi K Tóth, Réka Urbancsek, Alexandra Kiss, Kitti B Kovács, Ferenc Sarkady, Attila Nagy, Anna V. Oláh, László Nagy, Marcell Clemens, László Csiba, Zoltán Csanádi

“…The effect of pulmonary vein isolation (PVI) on fibrinolytic and endothelial activation with currently applied periprocedural anticoagulation has not been explored. We measured markers of fibrinolysis and endothelium activation before and after PVI with the second-generation cryoballoon (Cryo), pulmonary vein ablation catheter (PVAC-Gold), and irrigated radiofrequency (IRF). …”
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Wound irrigation and peritoneal lavage with antiseptic/antibiotic solution before wound closure during gastrointestinal surgery: a systematic review and meta-analysis by Motoi Uchino, Koji Tamura, Shinsuke Nomura, Seiichi Shinji, Keita Kouzu, Hiroji Shinkawa, Tomohiro Ishinuki, Toru Mizuguchi, Hiroki Ohge, Seiji Haji, Junzo Shimizu, Yasuhiko Mohri, Chizuru Yamashita, Yuichi Kitagawa, Katsunori Suzuki, Motomu Kobayash, Masahiro Kobayashi, Yuki Hanai, Hiroshi Nobuhara, Hiroki Imaoka, Masahiro Yoshida, Toshihiko Mayumi, Hiroki Ikeuchi, on behalf of SSI Prevention Guideline Committee in Japan Society for Surgical Infection

“…Although it has recently been reported that washing with antiseptic/antibiotic solution can prevent SSI in clean surgery, the clinical impact in gastrointestinal surgery is still uncertain. …”
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MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty – protocol for a double-blind, randomised controlled proof-of... by Andrew Clegg, James Wason, Miles Witham, Nina Wilson, Claire J Steves, Helen C Hancock, Avan A P Sayer, Leanne Marsay, Claire McDonald, Thomas von Zglinicki, Katherine J Rennie, Penny Bradley, Stephen Connolly, Shaun Hiu, Laura Robertson, Laura Simms, Alison J Steel, Bryony Storey

“…Introduction Skeletal muscle dysfunction is central to both sarcopenia and physical frailty, which are associated with a wide range of adverse outcomes including falls and fractures, longer hospital stays, dependency and the need for care. Resistance training may prevent and treat sarcopenia and physical frailty, but not everyone can or wants to exercise. …”
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South to south collaboration: advancing quality of abortion care through health care professionals exchange program by Abraham Fessehaye Sium, Wondimu Gudu, Abrham Getachew, Diomede Ntasumbumuyange, Polyphile Nithinyurwa, Tamrat Endale Woldemichael, Delayehu Bekele

“…Abstract Background South-South Cooperation (SSC) is recognized as a vital component of goal 17 – ‘Partnerships for the goals’ within the SDGs and countries in the global south has been utilizing this cooperation mainly in research. …”
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Perbedaan Efek Daya Hambat Jus Kulit Buah Manggis dengan Air Rebusan Kulit Buah Manggis sebagai Antibakteri terhadap Bakteri Gram-Positif (Staphylococcus aureus dan Streptococcus p... by Nani Hendriani, Netti Suharti, Julizar .

“…Six paper disks treated with before mentioned treatment was putted on a petri dish which previously has been isolated with both of those bacteria incubated for 24 hour at temperature of 37º celcius. …”
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The Role of EGFR/PI3K/Akt/cyclinD1 Signaling Pathway in Acquired Middle Ear Cholesteatoma by Wei Liu, Hongmiao Ren, Jihao Ren, Tuanfang Yin, Bing Hu, Shumin Xie, Yinghuan Dai, Weijing Wu, Zian Xiao, Xinming Yang, Dinghua Xie

“…Epidermal growth factor (EGF) is one of the most important cytokines which has been shown to play a critical role in cholesteatoma. …”
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Genomic adaptation of Clostridium perfringens to human intestine by Ke Wu, Juan Wang, Zelin Yan, Yanyan Zhu, Shaolin Wang, Bo Fu, Chengtao Sun, Ruichao Li, Edward M. Fox, Séamus Fanning, Li Bai, Yang Wang, Yizhi Tang, Zhe Yin, Rong Zhang, Hongning Wang

“…However, genomic investigation of C. perfringens isolates from the human population has been lacking. This study aims to fill this knowledge gap by examining the genomic characteristics of C. perfringens isolates from 699 individuals at a provincial hospital in China. …”
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THE АNAPA AMPELOGRAPHIC COLLECTION IS THE LARGEST CENTER OF VINE GENE POOL ACCUMULATION AND RESEARCH IN RUSSIA by M. I. Pankin, V. S. Petrov, A. A. Lukianova, E. T. Ilnitskaya, G. E. Nikulushkina, A. G. Kovalenko, V. А. Bolshakov

“…The collection has given birth to twenty seven varieties and elite forms, of which twelve varieties have been sent to the State Committee for the Testing of New Varieties of Agricultural Plants (Pluto, Muzhestvenniy (Courageous), Gordiy (Proud), Maran, Varvarovsky, Harmony, Progress, Gorniy (Mountaneous), Saturn, Dimitry, Vladimir, Kurchansky). …”
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Robust and Long-Lasting Immunity and Protection in Mice Induced by Lipopolyplex-Delivered mRNA Vaccines Expressing the Prefusion Protein of Respiratory Syncytial Virus by Xuchang Shan, Ruiwen Han, Xueting Cheng, Jialuo Bing, Zhenyong Qi, Shucai Sun, Tangqi Wang, Qiaohong Chu, Yao Deng, Desheng Zhai, Wenjie Tan

“…Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in infants and children. mRNA vaccines based on the lipopolyplex (LPP) platform have been previously reported, but they remain unapplied in RSV vaccine development. …”
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Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity by Yang Wang, Jianguo Xu, Wanchun You, Haitao Shen, Xiang Li, Zhengquan Yu, Haiying Li, Gang Chen

“…However, in experimental subarachnoid hemorrhage (SAH), the role of Rufy3 has not been investigated. Consequently, we aimed to investigate the potential role of Rufy3 in an in vivo model of SAH-induced early brain injury (EBI). …”
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The effects of altitude training on hormonal response in professional cyclists by Raphael Faiss, Bastien Krumm, Basile Moreillon, Lena Mettraux, Julian Wackernell, James Spragg, Martin Faulhaber

“…., increase in hemoglobin mass (Hbmass)), improved oxygen delivery or peripheral adaptations at the muscle level have been thoroughly investigated in the past decades. …”
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Functional interaction between receptor tyrosine kinase MET and ETS transcription factors promotes prostate cancer progression by Elisa Carouge, Clémence Burnichon, Martin Figeac, Shéhérazade Sebda, Nathalie Vanpouille, Audrey Vinchent, Marie‐José Truong, Martine Duterque‐Coquillaud, David Tulasne, Anne Chotteau‐Lelièvre

“…However, the collaboration of these factors in prostate cancer progression has not yet been investigated. Here, we show, using cell models of advanced prostate cancer, that ETS translocation variant 1 (ETV1) and transcriptional regulator ERG (ERG) transcription factors (members of the ETS family) promote tumour properties, and that activation of MET signalling enhances these effects. …”
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Study on the Regulated Cell Death of Hypertrophic H9c2 Cells Induced by Au:Ag Nanoparticles by Galindo-Padrón AG, Lorenzo-Anota HY, Rueda-Munguía M, García-Carrasco A, Gaitán López M, Vázquez-Garza E, Campos-González E, Lozano O, Cholula-Díaz JL

“…Andrés G Galindo-Padrón,1,&ast; Helen Yarimet Lorenzo-Anota,2,3,&ast; Mayte Rueda-Munguía,2,3 Alejandra García-Carrasco,1 Mabel Gaitán López,1 Eduardo Vázquez-Garza,2 Enrique Campos-González,4 Omar Lozano,2,3,5 Jorge L Cholula-Díaz1 1School of Engineering and Sciences, Tecnologico de Monterrey, Monterrey, Nuevo Leon, Mexico; 2Institute for Obesity Research, Tecnologico de Monterrey, Monterrey, Nuevo Leon, Mexico; 3School of Medicine and Health Sciences, Tecnologico de Monterrey, Monterrey, Nuevo Leon, Mexico; 4Departamento de Física, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac, Mexico; 5Cátedra de Cardiología y Medicina Vascular, Tecnologico de Monterrey, Monterrey, Nuevo León, México&ast;These authors contributed equally to this workCorrespondence: Omar Lozano; Jorge L Cholula-Díaz, Email omar.lozano@tec.mx; jorgeluis.cholula@tec.mxBackground and Aim: Over the past years, noble metal-based nanoparticles have been extensively investigated for their applications in nanomedicine. …”
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Clinicopathologic characteristics, therapeutic modalities and survival outcomes of plasmablastic lymphoma: A real-world study by Yan-Hua Zheng, Kun Xie, Hong-Yuan Shen, Zhuo Wan, Shan Gao, Wen-Rui Sun, Guang-Xun Gao, Li Liu, Juan Feng

“…Neither a standardized regimen nor a consensus for PBL treatment has been established. Material and methods We retrospectively analyzed the clinicopathologic characteristics, therapeutic modalities and survival outcomes of 418 patients registered in the Surveillance, Epidemiology, and End Results (SEER) database from 2008 to 2016 and 21 (19 treated) patients in our institution. …”
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Pengembangan Auto-AI Model Generatif Analisis Kompleksitas Waktu Algoritma Untuk Data Multi-Sensor IoT Pada Node-RED Menggunakan Extreme Learning Machine by Imam Cholissodin, Dahnial Syauqy, Dwi Ady Firmanda, Ibrahim Aji, Edy Rahman, Syazwandy Harahap, Fernando Septino

“…Namun dengan perkembangan teknologi komputer untuk AI, Machine Learning maupun Deep Learning, algoritma dengan basis AI tersebut, dalam penelitian ini dikembangkan untuk menemukan solusi general persamaan model T(n) secara otomatis dari desain algoritma sederhana atau kompleks. …”
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Engineering a live-attenuated porcine reproductive and respiratory syndrome virus vaccine to prevent RNA recombination by rewiring transcriptional regulatory sequences by Liwei Li, Jinxia Chen, Zhengda Cao, Ziqiang Guo, Jiachen Liu, Yanjun Zhou, Guangzhi Tong, Fei Gao

“…The prevalence and variation of porcine reproductive and respiratory syndrome virus (PRRSV) in China have been increasing in complexity due to extensive interlineage recombination. …”
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Seasonal variations and comparative nutritional composition of hatchery-reared, hatchery-released, and wild black rockfish (Sebastes schlegelii) by Liu Wang, Liu Wang, Yunhai He, Xu Wei, Xinyan Liang, Xinyan Liang, Ruonan Zhang, Ruonan Zhang, Qi Liu, Qi Liu, Chenqi Wang, Chenqi Wang, Jinfeng Chen, Jinfeng Chen, Meiyuan Li, Meiyuan Li, Zhi Ma, Shaodong Qu

“…Stock enhancement has been launched in response to wild populations decline. …”
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Exogenous cystine increases susceptibility of drug-resistant Salmonella to gentamicin by promoting oxidation of glutathione metabolism and imbalance of intracellular redox levels by Junyuan Du, Junyuan Du, Zhiyi Wu, Zhiyi Wu, Chunyang Zhu, Chunyang Zhu, Heng Yang, Heng Yang, Feike Zhao, Feike Zhao, Binghu Fang, Binghu Fang

“…Through the application of metabolomics, the underlying metabolic mechanisms by which cystine exerts its effects on Salmonella have been elucidated, offering a novel perspective in the domain of metabolic reprogramming aimed at counteracting drug resistance. …”
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