The Effects of Oral Semaglutide on Hepatic Fibrosis in Subjects with Type 2 Diabetes in Real-World Clinical Practice: A Post Hoc Analysis of the Sapporo-Oral SEMA Study by Hiroya Kitsunai, Yuka Shinozaki, Sho Furusawa, Naoyuki Kitao, Miki Ito, Hiroyoshi Kurihara, Chiho Oba-Yamamoto, Jun Takeuchi, Akinobu Nakamura, Yumi Takiyama, Hiroshi Nomoto

“…Glucagon-like peptide-1 receptor agonists are useful treatment options for MASLD; however, the efficacy of oral semaglutide in treating liver steatosis/fibrosis has not been fully elucidated. Methods: A secondary analysis of a multicenter, retrospective, observational study investigating the efficacy and safety of oral semaglutide in Japanese subjects with type 2 diabetes in a real-world clinical setting (the Sapporo-Oral SEMA study) was conducted. …”
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Cannabis consumption and risk of asthma: a systematic review and meta-analysis by Ajay Malvi, Mahalaqua Nazli Khatib, Ashok Kumar Balaraman, R. Roopashree, Mandeep Kaur, Manish Srivastava, Amit Barwal, G. V. Siva Prasad, Pranchal Rajput, Rukshar Syed, Gajendra Sharma, Sunil Kumar, Mahendra Pratap Singh, Ganesh Bushi, Nagavalli Chilakam, Sakshi Pandey, Manvinder Brar, Rachana Mehta, Sanjit Sah, Abhay M. Gaidhane, Muhammed Shabil, Afukonyo Shidoiku Daniel

“…Abstract Background Cannabis is the third most widely used psychoactive substance globally, and its consumption has been increasing, particularly with the growing trend of legalization for medicinal and recreational use. …”
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Pan-cancer analysis of the transcriptional expression of histone acetylation enzymes in solid tumors defines a new classification scheme for gliomas by Junhao Zhang, Lingbo Li, Aiwei Tang, Chucheng Wang, Yupeng Wang, Yongqi Hu, Guangting He, Guangting He, Wangjun Liao, Wangjun Liao, Wangjun Liao, Rui Zhou

“…IntroductionThe altered expression of genes encoding histone acetyltransferases (HATs) and histone deacetylases (HDACs) has been implicated in the tumorigenesis and progression of various solid tumors. …”
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Sustainable alternative of palm wine analogue from different tiger nut milk-sugar syrup blends for local production by Adindu O. Onyeodili, Gabriel I. Okafor, Chigozie F. Okoyeuzu, Onyekachukwu Chukwuebuka Nduka, Queency N. Okechukwu, Mouandhe Imamou Hassani, Szymon Juchniewicz, Katarzyna Leicht, Charles Odilichukwu R. Okpala, Małgorzata Korzeniowska, Raquel P.F. Guiné

“…Importantly, the tiger nut milk-sugar syrup medium has been pitched with palm wine dreg (inoculum source) between fermentation time 26–30 h, and temperature 29.8°–32°C. …”
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Utilizing multidisciplinary mobile outreach clinics to provide comprehensive diabetic foot care to patients experiencing homelessness by Kris M. Boelitz, MD, Jaeyoung Lee, BS, Michael D. Pepin, BS, Yiming Zhang, MS, Mallory Gibbons, MSN, NP, Frances J. Lagana, DPM, Shahida Balaparya, EdD, MBA, RVT, Lindsey Carr, Jessin Varghese, BS, NP, Caitlin Sorensen, MD, Jessica P. Simons, MD, MPH, Douglas Jones, MS, MD, Andres Schanzer, MD, Tammy T. Nguyen, MD, PhD

“…Results: From June 2020 to November 2023, a total of 241 patients were seen at seven multidisciplinary mobile clinics. All patients received health resources and donated items including new socks and shoes. …”
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TCR transgenic clone selection guided by immune receptor analysis and single-cell RNA expression of polyclonal responders by Nincy Debeuf, Sahine Lameire, Manon Vanheerswynghels, Julie Deckers, Caroline De Wolf, Wendy Toussaint, Rein Verbeke, Kevin Verstaen, Hamida Hammad, Stijn Vanhee, Bart N Lambrecht

“…To overcome this detection problem, adoptive transfer of a cohort of T cells purified from T cell receptor (TCR) transgenic donors has been extensively used but is not readily available for emerging pathogens. …”
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Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease by Lindsey Van Haute, Petra Páleníková, Jia Xin Tang, Pavel A Nash, Mariella T Simon, Angela Pyle, Monika Oláhová, Christopher A Powell, Pedro Rebelo-Guiomar, Alexander Stover, Michael Champion, Charulata Deshpande, Emma L Baple, Karen L Stals, Sian Ellard, Olivia Anselem, Clémence Molac, Giulia Petrilli, Laurence Loeuillet, Sarah Grotto, Tania Attie-Bitach, Jose E Abdenur, Robert W Taylor, Michal Minczuk

“…Within this group, an increasing number of families have been identified, where Mendelian genetic disorders implicate defective mitochondrial RNA biology. …”
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Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) study by MR Gonzalez, C Cardenas-Iniguez, DE Linares, S Wonnum, K Bagot, EJ White, A Cuan, S DiMatteo, YD Akiel, P Lindsley, JC Harris, E Perez-Amparan, TD Powell, Comité Organizador Latino de City Heights (COLCH), G Dowling, D Alkire, WK Thompson, TM Murray

“…The ABCD Study® data has been used in over 1100 peer-reviewed publications since its first data release in 2018. …”
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ECG‐based epileptic seizure prediction: Challenges of current data‐driven models by Sotirios Kalousios, Jens Müller, Hongliu Yang, Matthias Eberlein, Ortrud Uckermann, Gabriele Schackert, Witold H. Polanski, Georg Leonhardt

“…Currently, no such system is available to meet this need. Previous studies suggest that changes in the electrocardiogram (ECG) precede seizures by several minutes. …”
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Ecological risk assessment of future suitable areas for Piper kadsura under the background of climate change by Shimeng Li, Yuanxin Li, Mingli Hu, Mingli Hu, Yankun Li, Yankun Li, Mingrong Yang, Shi Wang, Shi Wang, Wei Yu, Wei Yu, Chunsong Cheng, Qiqing Cheng, Qiqing Cheng

“…The market demand of P. kadsura is huge, but its wild resources are scarce and artificial cultivation methods have not been established, which leads to a situation with strong contradiction and imbalance between supply and demand.MethodsIn this study, 303 sample of distribution data for P. kadsura in China were collected, 33 environmental variables related to terrain, climate and soil were analyzed and the suitable habitats of P. kadsura during various periods were predicted by MaxEnt model and ArcGIS software, aiming to provide a basis for scientific cultivation and effective utilization of resources.ResultsThe results indicated that precipitation and temperature were significant factors in the distribution of P. kadsura. …”
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The association of visceral and subcutaneous fat areas with phenotypic age in non-elderly adults, mediated by HOMA-IR and HDL-C by Yuanhong Liu, Min Xu, Liqing Wang, Linyun Meng, Mengran Li, Shumin Mu

“…Abdominal subcutaneous adipose tissue, visceral adipose tissue, the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR), and high-density lipoprotein cholesterol (HDL-C) have all been shown to correlate with ageing; however, the connections between these factors and PhenoAge are still insufficiently investigated. …”
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Single-cell profiling of SLC family transporters: uncovering the role of SLC7A1 in osteosarcoma by Yan Liao, Junkai Chen, Hao Yao, Ting Zheng, Jian Tu, Weidong Chen, ZeHao Guo, Yutong Zou, Lili Wen, Xianbiao Xie

“…Over the past three decades, therapeutic outcomes have plateaued, underscoring the critical need for innovative therapeutic targets. Solute carrier (SLC) family transporters have been implicated in the malignant progression of a variety of tumors, however, their specific role in osteosarcoma remains poorly understood. …”
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Identification of a transcription factor AoMsn2 of the Hog1 signaling pathway contributes to fungal growth, development and pathogenicity in Arthrobotrys oligospora by Qianqian Liu, Kexin Jiang, Shipeng Duan, Na Zhao, Yanmei Shen, Lirong Zhu, Ke-Qin Zhang, Jinkui Yang

“…Introduction: Arthrobotrys oligospora has been utilized as a model strain to study the interaction between fungi and nematodes owing to its ability to capture nematodes by developing specialized traps. …”
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Blue rings in trees and shrubs as indicators of early and late summer cooling events at the northern treeline by Agata Buchwal, Agata Buchwal, Pawel Matulewski, Ylva Sjöberg, Alma Piermattei, Alma Piermattei, Alan Crivellaro, Alan Crivellaro, Angela Balzano, Maks Merela, Luka Krže, Katarina Čufar, Alexander V. Kirdyanov, Alexander V. Kirdyanov, Tatiana Bebchuk, Tito Arosio, Ulf Büntgen, Ulf Büntgen, Ulf Büntgen

“…However, wood anatomical anomalies that likely reflect temperature-induced reductions in cell wall lignification, the so-called Blue Rings (BRs), have not yet been systematically investigated in trees and shrubs in northern Europe. …”
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Molecular docking and dynamics studies to identify novel active compounds targeting potential breast cancer receptor proteins from an indigenous herb Euphorbia thymifolia Linn [version 3; peer review: 2 approved] by ShamaPrasada K, Reshma Kumarchandra, Vasavi Kumblekar, K Sreedhara Ranganath Pai, Suman Manandhar, Sharada Rai, Rajeshwari Shastry

“…Euphorbia thymifolia L is a widely growing tropical herb that has been reported to have various ethnopharmacological properties. …”
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5-aminolevulinic acid in photodynamic therapy used in dermatology as a method of treating acne vulgaris. by Karolina Sacher, Krystyna Zabojska, Aleksandra Cygnarowicz, Mariola Turemka, Negar Hosseinnejad, Aneta Klaudia Wojtas, Mikołaj Biskupski, Urszula Korotko, Kinga Witowska, Aneta Mandziuk

“…One such indication is precisely the use of 5-aminolevulinic acid in photodynamic therapy for the treatment of acne lesions. The given issue has been widely discussed on the basis of a number of research papers from around the world, whose publications have promising results. …”
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Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration- Tobacco w... by Erfan Tasdighi, Kunal K. Jha, Zeina A. Dardari, Ngozi Osuji, Tanuja Rajan, Ellen Boakye, Michael E. Hall, Carlos J. Rodriguez, Andrew C. Stokes, Omar El Shahawy, Emelia J. Benjamin, Aruni Bhatnagar, Andrew P. DeFilippis, Michael J. Blaha

“…Therefore, there is the need for sufficiently powered well-phenotyped datasets to fully elucidate the CVD risks associated with non-cigarette tobacco products. …”
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Assessment of Attentional Functioning in Health Professionals of a Brazilian Tertiary Referral Hospital for COVID-19 by Eelco van Duinkerken, Guilherme J. Schmidt, Ana Lúcia Taboada Gjorup, Carolina Ribeiro Mello, André Casarsa Marques, Áureo do Carmo Filho, Paula Regina Yuri Fukusawa, Simone Gonçalves de Assis, Júlio Cesar Tolentino, Sergio L. Schmidt

“…The substantial exposure group consisted of participants with 24 hours/week or more direct contact with COVID-19 patients. …”
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Regeneration of Tracheal Tissue in Partial Defects Using Porcine Small Intestinal Submucosa by Nelson Bergonse Neto, Lianna Ferrari Jorge, Julio C. Francisco, Bruna Olandoski Erbano, Barbara Evelin Gonçalves Barboza, Larissa Luvison Gomes da Silva, Marcia Olandoski, Katherine Athayde Teixeira de Carvalho, Luiz Felipe Pinho Moreira, Jose Rocha Faria Neto, Eltyeb Abdelwahid, Luiz Cesar Guarita-Souza

“…An alternative treatment may be the use of porcine small intestinal submucosa (SIS). It has been used as graft material for bioengineering applications and to promote tissue regeneration. …”
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Entomological Investigations, Seasonal Fluctuations and Impact of Bioclimate Factors of Phlebotomines Sand Flies (Diptera: Psychodidae) of an Emerging Focus of Cutaneous Leishmania... by Fatima Zahra Talbi, Abdelhakim El Ouali Lalami, Mouhcine Fadil, Mohamed Najy, Hassan Ech-Chafay, Mohamed Lachhab, Said Lotfi, Nordine Nouayti, Khadija Lahouiti, Chafika Faraj, Abdellatif Janati Idrissi

“…The climatic factor of relative humidity has been judged of being negatively correlated. The wind speed does not have any impact on the relative abundance of all species. …”
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