Hemodiafiltration with endogenous reinfusion for uremic toxin removal in patients undergoing maintenance hemodialysis: a pilot study by Renhua Lu, Yan Fang, Wangshu Wu, Xiaojun Zeng, Tingting Liu, Yue Qian, Yuanyuan Xie, Yijun Zhou, Leyi Gu

“…Objective To delineate the efficacy and safety profile of hemodiafiltration with endogenous reinfusion (HFR) for uremic toxin removal in patients undergoing maintenance hemodialysis (MHD).Methods Patients who have been on MHD for a period of at least 3 months were enrolled. …”
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Results of propagation of Fagus silvatica L. plants in vitro by Mykola Lisovyi, Andrii Ivaniuk

“…A number of experimental studies have been conducted regarding the modification of the main stages of microcloning of Fagus silvatica L., namely: features of decontamination of plant material, initiation of growth and rhizogenesis of explants and adaptation of clones to in vivo conditions. …”
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Effect of Arthrospira platensis (Spirulina) as a dietary supplement during transition period in dairy buffaloes by Giuseppe De Rosa, Vittoria L. Barile, Carmela M.A. Barone, Claudia Lambiase, Francesco Serrapica, Giovanna De Matteis, Emanuela Rossi, Corrado Pacelli

“…To date, no similar research has been reported on the buffalo species. Therefore, we investigated the effect of Spirulina on body condition score (BCS), yield and quality of milk, and oxidative stress response through the assessment of reactive oxygen metabolites (d-ROMs test) and the biological antioxidant potential (BAP test) of twenty-four Italian Mediterranean buffaloes. …”
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Analyzing Iran's Legislative Criminal Policy in Dealing with Environmental Terrorism, Emphasizing the Need for Criminalization and Preventive Measures by behrouz sepehri, Nourooz Kargari, mohammad ashouri, ghassem ghassemi

“…Introduction: environmental security, is a necessary condition for the health and continuity of human life on earth and due to the vital, widespread and inevitable dependence of humans on the environment, if the environmental security is taken away and it is removed from the possibility of healthy living, as a result of the goal or the means of placing the environment, following environmental terrorism, with various methods such as polluting the natural and man-made environment with dangerous substances, extensive and irreparable damage is caused to human life and health And often, the most obvious effects of damage to the safety and health of the environment appear in the form of epidemics, and on the other hand, the cross-border effects of such actions and the possibility of transferring the said effects from through the flow of air or water or the carriers of disease agents to countries and regions beyond the place of the accident, and the possibility of spreading some of these effects on the life and health of future generations, reveals the seriousness of the danger of environmental terrorism, hence, The purpose of this thesis is to explain the vital necessity of legal, technical and specialized contrast, against environmental terrorism in the form of an efficient criminal policy with international interaction, with emphasizing the extent and irreparability of the effects caused by environmental terrorism, and the necessity and importance of preventive measures.Materials and Methods:  In terms of the goal, the current research will cause expansion the legal theories and doctrine and complete the previous theories with the fundamental method of the research results, and also with the practical approach, effective practical solutions to deal with environmental terrorism will be presented, and on the other hand, the materials and information used in the research, They are collected with the library method and after collecting and categorizing the materials and information, with the descriptive-analytical method, the findings and the collected materials are analyzed logically and legally and they are used as the basis of citation to strengthen the approach of the researcher in the relevant subject.Results: In a comprehensive and efficient criminal policy to contrast against environmental terrorism, in addition to criminalizing this criminal phenomenon along with the real conceptology and in addition to recognizing its specific elements, it is expected that with the necessary criminal measures, specialized measures will be taken to identify and criminalize behaviors that it has a preliminary aspect to dangerous crimes, and it is possible that environmental terrorism is also committed through them, and therefore, in order to prevent this criminal phenomenon, criminalize such behaviors in the form of obstruction crimes seems necessary.Discussion: In Iran's criminal system, environmental terrorism has not been considered as an independent criminal behavior, with specific elements and specific conditions, However, due to the inherent of the behaviors related to environmental terrorism, this type of terrorism is inherently reprehensible, and as a rule, it can be included in various legal elements in the criminal laws, and on the other hand, due to the analogy of some elements of this criminal phenomenon with the destruction of the earth, According to jurisprudence, significant examples of environmental terrorism behaviors can be considered as examples of corruption in the land subject to Article 286 of the Islamic Penal Code (approved in 2012). …”
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Dissemination of IncQ1 Plasmids Harboring NTE_KPC-IId in a Brazilian Hospital by Camila Maria dos Santos Boralli, Julian Andres Paganini, Rodrigo Silva Meneses, Camila Pacheco Silveira Martins da Mata, Edna Marilea Meireles Leite, Anita C. Schürch, Fernanda L. Paganelli, Rob J. L. Willems, Ilana L. B. C. Camargo

“…The <i>bla</i>_KPC gene has also been found in <i>non-Tn4401 elements</i> (NTE_KPC). …”
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Novel loci for triglyceride/HDL-C ratio longitudinal change among subjects without T2D by Lihua Wang, Siyu Wang, Jason A. Anema, Vaha A. Moghaddam, Yanli Lu, Shiow Lin, E. Warwick Daw, Allison L. Kuipers, Iva Miljkovic, Michael Brent, Gary J. Patti, Bharat Thygarajan, Joseph M. Zmuda, Michael A. Province, Ping An

“…Our GWAS identified a significant locus at the LPL (P = 1.58e-9) for ΔTHR; this locus has been reported before influencing baseline THR levels. …”
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Generation of Insulin-Producing Cells from Canine Adipose Tissue-Derived Mesenchymal Stem Cells by Takahiro Teshima, Keiji Okamoto, Kazuho Dairaku, Tomokazu Nagashima, Masaki Michishita, Ryohei Suzuki, Hirotaka Matsumoto, Hidekazu Koyama

“…The potential of mesenchymal stem cells (MSCs) to differentiate into nonmesodermal cells such as pancreatic beta cells has been reported. New cell-based therapy using MSCs for diabetes mellitus is anticipated as an alternative treatment option to insulin injection or islet transplantation in both human and veterinary medicine. …”
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Depression and Temporal Lobe Epilepsy: Expression Pattern of Calbindin Immunoreactivity in Hippocampal Dentate Gyrus of Patients Who Underwent Epilepsy Surgery with and without Com... by Luciana D’Alessio, Hector Konopka, Patricia Solís, Laura Scévola, Mónica Fernandez Lima, Claudio Nuñez, Eduardo Seoane, Silvia Oddo, Silvia Kochen

“…Changes in calbindin (CB) expression have been reported in patients with temporal lobe epilepsy (TLE) with controversial implications on hippocampal functions. …”
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Therapeutic effect and potential mechanism of Fufang Danshen dripping pills for stable coronary heart disease: a randomized controlled trial by Li-qin Meng, Li-qin Meng, Pei-ying Huang, Qing-min Li, Yu-chao Feng, Yu-chao Feng, Yu-chao Feng, Ding-jian Li, Guang-long Wu, Bo-wen Ao, Guo-chao Wu, Guo-xiong Zhang, Bo-jun Chen, Bo-jun Chen, Bo-jun Chen

“…By integrating these findings with network pharmacology targets, we highlighted the potential roles of LPL, CD36, FABPpm, L-FABP, LCAT, and CEPT in fat digestion, absorption, and metabolism pathways, suggesting their involvement in FFDS's treatment of SCHD by reducing triglycerides.ConclusionIn individuals with SCHD, the administration of FFDS has been shown to effectively reduce circulating triglyceride levels and decrease the frequency of angina episodes. …”
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Effect of prenatal multiple micronutrient supplementation on birth weight in Ethiopia: protocol for a pragmatic cluster-randomised trial by Joanna Schellenberg, Charles Opondo, Tanya Marchant, Lars Åke Persson, Masresha Tessema, Atkure Defar, Alemneh Kabeta Daba, Girum Taye, Senait Alemayehu, Elias Asfaw, Anene Tesfa, Bedasa Tessema, Kalkidan Zenebe

“…Introduction This programme effectiveness study responds to the need for evidence of the effect on birth weight of switching from iron-folic acid supplementation to multiple micronutrient supplementation as part of routine antenatal care in Ethiopia. …”
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Genome-Wide Profiling of Human Papillomavirus DNA Integration into Human Genome and Its Influence on PD-L1 Expression in Chinese Uygur Cervical Cancer Women by Feng Yang-chun, Wang Sen-yu, Zhang Yuan, Huang Yan-chun

“…Their HPV integration situation has never been reported. We aimed to investigate the integration situation of 20 subtypes of HPV gene into host cell genome in Chinese Uygur cervical cancer patients; meanwhile, we explored the influence of gene integration on PD-L1 expression. …”
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Epigenetics disruptions enabled by porphyrin-derived metal-organic frameworks disarm resistances to sonocatalytic ROS anti-tumor actions by Yan Zhang, Dou Du, Chao Fang, Xin Yu, Yujia Fang, Xinyu Liu, Di Ou, Haohao Yin, Hui Liu, Taixia Wang, Lu Lu, Xiaolong Li, Kun Zhang

“…Ultrasound-triggered Auranofin release from PCN224@Au has been validated to blockade the deubiquitinating process and drive proteasome-mediated target protein degradation. …”
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Isocitrate Dehydrogenase 1 and 2 Mutations in Pediatric Neuroblastoma Patients by Emre LEVENTOGLU, Gurses SAHIN, Sule YESIL, Ceyhun BOZKURT, Nazmiye YUKSEK, Ali FETTAH, Sule TOPRAK, Burcak KURUCU BILGIN, Emre CAPKINOGLU, Nilgun EROGLU, Sibel AKPINAR TEKGUNDUZ, Ayse Ulya ERTEM

“…IDH1 and IDH2 mutations have been found in many types of cancer, such as malignant gliomas, acute myeloid leukemias, chondrosarcoma, and thyroid carcinoma. …”
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Poly (ADP-ribose) (PAR) levels in Peripheral Blood Mononuclear Cells (PBMC) during peri-implantation and early pregnancy in buffalo cows by Giovanna De Matteis, Anna Reale, Michele Zampieri, Emanuela Rossi, Federica Signorelli, Olimpia Barbato, Vittoria Lucia Barile

“…However, further studies are needed to clarify the role of PAR modification during the establishment and maintenance of pregnancy in livestock. …”
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The role of inflammatory system genes in individual differences in nonverbal intelligence by R. F. Enikeeva, A. V. Kazantseva, Yu. D. Davydova, R. N. Mustafin, Z. R. Takhirova, S. B. Malykh, Y. V. Kovas, E. K. Khusnutdinova

“…Gene-by-environment interaction models, which determined interindividual differences in nonverbal intelligence, have been constructed: sibship size (number of children in a family) and smoking demonstrated a modulating effect on association of the TNF/LTA (rs1041981) (β = 2.08; βST = 0.16; p = 0.001) and P2RX7 (rs2230912) (β = –1.70; βST = –0.10; p = 0.022) gene polymorphisms with nonverbal intelligence. …”
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Enhanced myofibroblast differentiation of eMSCs in intrauterine adhesions by Jun Song, Meiqi Li, Yuan Tao, Yumeng Li, Canrong Mai, Jingting Zhang, Lan Yao, Shaoquan Shi, Jianyong Xu

“…Among proposed hypotheses on IUA development, the reduced endometrial regeneration resulting from loss of functional stem cells has been proposed as the key factor affecting the IUA prognosis. …”
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2′-Hydroxycinnamaldehyde induces ROS-mediated apoptosis in cancer cells by targeting PRX1 and PRX2 by Yae Jin Yoon, Yu-Jin Lee, Jiyeon Choi, Seung-Wook Chi, Sangku Lee, Kyung Chan Park, Byoung-Mog Kwon, Dong Cho Han

“…However, the molecular target of HCA for ROS induction has not been identified. In the present study, we identified peroxiredoxin 1 (PRX1) and peroxiredoxin 2 (PRX2) as target proteins of HCA using affinity chromatography, and further confirmed these association using a cellular thermal shift assay (CETSA). …”
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Gambaran Slide Malaria Berdasarkan Sediaan Darah dari Kepulauan Siberut Mentawai Periode Oktober 2011 – Januari 2012 by Adeline Sacharissa Firdaus, Nuzulia Irawati, Arni Amir

“…Research done by microscopic examination of thick and thin blood preparations from peripheral blood samples that had been daubed with Giemsa staining to determine how the incidence, distribution of malaria by sex, distribution of malaria by species and Parasite Count. …”
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Beyond identification of familial hypercholesterolemia: Improving downstream visits and treatments in a large health care system by Harin Lee, Tarun Kadaru, Ruth Schneider, Taylor Triana, Carol Tujardon, Colby Ayers, Mujeeb Basit, Zahid Ahmad, Amit Khera

“…Several electronic health record (EHR) algorithms have been developed to improve identification of patients with FH. …”
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Security and religion in democratizing Tunisia: re-enacting surveillance through religious narratives and gendered dynamics by Fabrizio Leonardo Cuccu, Alessandra Bonci

“…Despite a process of democratization that started in 2011 and has often been described as successful (Stepan, 2012; Freedom House, 2015; Bugeja, 2016), until the recent backsliding process, some Tunisian national institutions have undergone little or no change. …”
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