NOX4 modulates breast cancer progression through cancer cell metabolic reprogramming and CD8+ T cell antitumor activity by Yingying Xiong, Yiming Weng, Shan Zhu, Jian Qin, Jia Feng, Xiaopeng Jing, Chao Luo, Wei Gong, Rui Sun, Min Peng

“…Although NADPH oxidase 4 (NOX4) has been implicated in various oncogenic processes, its exact function in breast cancer progression, metabolic reprogramming, and immune modulation remains unclear.MethodsWe used murine 4T1 and EO771 breast cancer models to generate NOX4 knockout (KO) cell lines via CRISPR/Cas9. …”
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High trophic similarity between non-native common carp and gibel carp in Turkish freshwaters: Implications for management by Sadi Aksu, Özgür Emiroğlu, Paride Balzani, J. Robert Britton, Esengül Köse, Irmak Kurtul, Sercan Başkurt, Oğuzcan Mol, Emre Çınar, Phillip J. Haubrock, Pinar Oztopcu-Vatan, Ali Serhan Tarkan

“…Although the detrimental ecological and economic effects of introducing freshwater fish species have been extensively documented, non-native freshwater fishes continue to be introduced in large numbers globally to enhance fisheries and aquaculture. …”
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Parathyroid carcinoma: impact of preoperative diagnosis on the choice of surgical procedure by Yoshitaka Kawai, Yo Kishimoto, Hisanobu Tamaki, Takashi Fujiwara, Ryo Asato, Koji Ushiro, Shogo Shinohara, Shinpei Kada, Shinji Takebayashi, Tsuyoshi Kojima, Shuya Otsuki, Masakazu Miyazaki, Yohei Kumabe, Koichi Omori

“…Although an intact parathyroid hormone (iPTH) threshold to suspect malignancy has not been established, six cases showed marked iPTH elevation exceeding 8.0 times the upper limit of normal. …”
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Akkermansia muciniphila and its metabolite propionic acid maintains neuronal mitochondrial division and autophagy homeostasis during Alzheimer’s disease pathologic process via GPR4... by Zifan Wang, Cai Wang, Boyu Yuan, Li Liu, Haoming Zhang, Mingqiang Zhu, Hongxia Chai, Jie Peng, Yanhua Huang, Shuo Zhou, Juxiong Liu, Liyong Wu, Wei Wang

“…In addition, short-chain fatty acids (SCFA) produced by intestinal microbiota metabolism have been considered to be important factors affecting central nervous system (CNS) homeostasis. …”
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Challenges in Predicting the Filtration Performance of a Novel Sewn Mask: Scale-up from Filter Holder to Mannequin Measurements by Audrey J. Dang, Benjamin M. Kumfer, J. Tyler Bertroche, Jane Olson Glidden, Christopher R. Oxford, Udayabhanu Jammalamadaka, Mary Ruppert-Stroescu, Alexander R. Scott, Jason A. Morris, Connie Gan, Jesse Hu, Bradley King, David I. A. Dhanraj, Shruti Choudhary, Pratim Biswas, Richard L. Axelbaum, Kathleen W. Meacham, Brent J. Williams

“…Abstract Novel designs and materials for filtering face-piece respirators (FFRs) have been disseminated in response to shortages during the COVID-19 pandemic. …”
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Association between cadherin-related family member 3 rs6967330-A and human rhinovirus-C induced wheezing in children by Hanhaoyu Fu, Ri De, Yu Sun, Yao Yao, Runan Zhu, Dongmei Chen, Yutong Zhou, Qi Guo, Linqing Zhao

“…However, the relation between rs6967330 variants of cadherin-related family member 3 (CDHR3) and wheezing induced by human rhinovirus (HRV)-C has not been determined. Methods A total of 11,756 respiratory specimens collected from hospitalized children with acute respiratory infections (ARIs) between September 2017 and March 2023 were screened for enterovirus (EV)/HRVs by the capillary electrophoresis-based multiplex PCR (CEMP) assay, and those positive only for HRVs were amplified and sequenced for HRV and CDHR3 genotyping. …”
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Expansion and Assessment of a Web-Based 24-Hour Dietary Recall Tool, Foodbook24, for Use Among Diverse Populations Living in Ireland: Comparative Analysis by Grace Bennett, Shuhua Yang, Laura A Bardon, Claire M Timon, Eileen R Gibney

“… BackgroundCurrently, the methods used to collect dietary intake data in Ireland are inflexible to the needs of certain populations, who are poorly represented in nutrition and health data as a result. …”
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Association between adult body shape index and serum levels of the anti-aging protein Klotho in adults: a population-based cross-sectional study of the NHANES from 2007 to 2016 by Li Gong, Jinghan Xu, Yiyang Zhuang, Liwei Zeng, Zhenfei Peng, Yuzhou Liu, Yinluan Huang, Yutian Chen, Fengyi Huang, Chunli Piao

“…Higher ABSI was associated with lower serum Klotho concentrations; however, this association did not seem to be significant in subjects with BMI ≥30 kg/m2.Further study is needed to verify the causality of this association and elucidate the underlying mechanisms.…”
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Impact of Self-Management Clustered Care on Psychological and Birth Outcomes in Gestational Diabetes by Tang S, Wang S, Wu J, Hu S, Lu T, Zhu M, Li J, Xue F

“…Shuting Tang,1,* Song Wang,1,* Jinyan Wu,1 Shoudi Hu,1 Tingting Lu,2 Minli Zhu,2 Jinzhi Li,1 Fang Xue1 1School of Nursing, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Maternity Ward, the First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fang Xue, School of Nursing, Bengbu Medical University, No. 2600 Donghai Avenue, Bengbu, Anhui, People’s Republic of China, Email 0700036@bbmu.edu.cnPurposes: To investigate the effects of a self-management-cluster-based pregnancy care model (SMB-CPCM) on the psychological status and delivery outcomes of pregnant women with gestational diabetes mellitus (GDM).Patients and Methods: A total of 120 pregnant women with GDM who had been filed and had regular obstetric examinations in a tertiary-level hospital in Bengbu City between 1 April 2023 and 1 April 2024 were included in the study using the convenience sampling method. …”
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Penerapan Metode Weighted Product untuk Seleksi Kelulusan Santri pada Sistem Informasi Wisuda Taman Pendidikan Al-Quran (TPA) Universitas Darussalam Gontor by Dihin Muriyatmoko, Triana Harmini, Muhamad Nuradi Arrahmantoro

“…To prioritize the review needs a multi-attribute weight value method, including Weight Product (WP). …”
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Biofilm Formation by Staphylococcus aureus Isolated from Food Contact Surfaces in the Dairy Industry of Jalisco, Mexico by María-Guadalupe Avila-Novoa, Maricarmen Iñíguez-Moreno, Oscar-Alberto Solís-Velázquez, Jean-Pierre González-Gómez, Pedro-Javier Guerrero-Medina, Melesio Gutiérrez-Lomelí

“…Therefore, vigilant food safety practices need to be implemented in the dairy industries regarding FCS to prevent food-borne infections and intoxications due to S. aureus contamination.…”
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AI for IMPACTS Framework for Evaluating the Long-Term Real-World Impacts of AI-Powered Clinician Tools: Systematic Review and Narrative Synthesis by Christine Jacob, Noé Brasier, Emanuele Laurenzi, Sabina Heuss, Stavroula-Georgia Mougiakakou, Arzu Cöltekin, Marc K Peter

“…In addition, traditional evaluation methods struggle to keep pace with AI’s rapid development. To ensure successful AI integration, flexible, fast-tracked assessment processes and proper assessor training are needed to maintain rigorous standards while adapting to AI’s dynamic evolution. …”
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Biological subphenotypes in patients hospitalized with suspected infection in Thailand: a secondary analysis of a prospective observational studyResearch in context by Prapassorn Poolchanuan, Taylor D. Coston, Viriya Hantrakun, Parinya Chamnan, Gumphol Wongsuvan, Pavan K. Bhatraju, Narisara Chantratita, Direk Limmathurotsakul, T. Eoin West, Shelton W. Wright

“…Summary: Background: Subphenotypes of infected patients have been reported in Europe and North America, but few studies have investigated populations in Southeast Asia. …”
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The prevalence and antimicrobial resistance of respiratory pathogens isolated from feedlot cattle in Canada by Porjai Rattanapanadda, Porjai Rattanapanadda, Dana Ramsay, Alyssa Butters, Calvin W. Booker, Sherry J. Hannon, Steve Hendrick, Joyce Van Donkersgoed, Brian N. Warr, Sheryl P. Gow, Paul S. Morley

“…NP swabs were collected from 16 animals in each enrolled group upon entry processing and later in the feeding period. Cattle from the same groups (not necessarily the same animals) were sampled at both timepoints. …”
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A perinatal psychiatry access program to address rural and medically underserved populations using telemedicine by Courtney King, Marie Hayes, Lizmarie Maldonado, Elizabeth Monter, Rubin Aujla, Erin Phlegar, Claire Smith, Liz Parker, Kerry Blome, Amanda Sandford, Edie Douglas, Constance Guille

“…Conclusions Adaptations made to psychiatry access program evident in Moms IMPACTT appear to be successful in meeting the specific needs of birthing people in the state of South Carolina. …”
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Synergistic enhancement of hydrophobic dental adhesives: autonomous strengthening, polymerization kinetics, and hydrolytic resistance by Burak Korkmaz, Erhan Demirel, Qiang Ye, Qiang Ye, Anil Misra, Anil Misra, Candan Tamerler, Candan Tamerler, Candan Tamerler, Paulette Spencer, Paulette Spencer, Paulette Spencer

“…The margin between the composite and tooth is initially sealed by a low-viscosity adhesive, but chemical, physical, and mechanical stresses work synergistically and simultaneously to degrade the adhesive, destroying the interfacial seal and providing an ideal environment for bacteria to proliferate. Our group has been developing self-strengthening adhesives with improved chemical and mechanical characteristics. …”
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Organotin(IV) trifluoromethanesulfonate chemistry: isolation and characterization of novel 1,10-phenanthroline-based derivatives by Cattey, Hélène, Plasseraud, Laurent

“…The reactivity of the hydroxo di-n-butyltin trifluoromethanesulfonato dimer complex [n-Bu2Sn(µ-OH)(H2O)(CF3SO3)]2 (1) toward 1,10-phenanthroline (phen) has been investigated, leading to the formation of two novel di-n-butyltin(IV) trifluoromethanesulfonate complexes [n-Bu2Sn(µ-OH)(phen)]2[CF3SO3]2 (5) and [n-Bu2Sn(phen)2][CF3SO3]2 (6), in which the tin atoms are bis-chelated by one and two bidentate phen ligands, respectively. …”
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Chiral Pesticides in Soil and Water and Exchange with the Atmosphere by Terry F. Bidleman, Andi D. Leone, Renee L. Falconer, Tom Harner, Liisa M.M. Jantunen, Karin Wiberg, Paul A. Helm, Miriam L. Diamond, Binh Loo

“…Estimates of microbial degradation rates for α-HCH in the eastern Arctic Ocean and an arctic lake have been made from the enantiomer fractions (EFs) and mass balance in the water column. …”
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TOPBP1 as a potential predictive biomarker for enhanced combinatorial efficacy of olaparib and AZD6738 in PDAC by Xiao-Mei Tang, Min-Min Shi, Jia-Cheng Wang, Yi-Jin Gu, Yu-Ting Dai, Qin-Xin Yang, Jia Liu, Ling-Jie Ren, Xin-Yun Liu, Chun Yang, Fang-Fang Ma, Ji-Bing Liu, Hong Yu, Da Fu, Yun-Feng Wang

“…DNA topoisomerase II-binding protein 1 (TOPBP1) plays a supportive role in regulating the DDR pathway, and its overexpression has been linked to the tumorigenesis of various cancers. …”
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Role of calcium overload-mediated disruption of mitochondrial dynamics in offspring neurotoxicity due to methylmercury exposure during pregnancy and lactation by Lingxu Kong, Huajie Yang, Jing Yang, Liujiangshan Jiang, Bin Xu, Tianyao Yang, Wei Liu

“…MeHg crosses the placental barrier and accumulates in the brain of the fetus, affecting the growth and development of the central nervous system. Although it has been demonstrated that MeHg induces neuronal calcium overload in the rat cerebral cortex, the role of calcium overload in MeHg-induced neurodevelopmental toxicity remains unclear. …”
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