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54881
Epidemiological Dynamics of Extended-Spectrum β-Lactamase- or AmpC β-Lactamase-Producing Escherichia coli Screened in Apparently Healthy Chickens in Uganda
Published 2021-01-01“…The dynamics of extended-spectrum β-lactamase- (ESBL-) and AmpC β-lactamase-producing bacteria (which are deadly groups of antimicrobial-resistant bacteria) have not been well understood in developing countries. This raises major concerns to antimicrobial resistance (AMR) control. …”
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54882
Contemporary survival outcomes of congenital systemic-to-pulmonary shunt in children with borderline pulmonary vascular resistant index compared to Eisenmenger syndrome
Published 2024-07-01“…Treatment options for PAH-CHD-predominantly left-to-right (L-R) shunt in children with borderline-high pulmonary vascular resistant index (PVRi) have been debated. We aimed to assess the treatment and survival of children with PAH-CHD-predominantly L-R shunt with borderline to high PVRi, using Eisenmenger syndrome (ES) for comparison. …”
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54883
The association between salivary oxytocin, age, and puberty in children with and without OCD
Published 2024-11-01“…Abstract The oxytocin system has been thought to contribute to obsessive-compulsive disorder (OCD). …”
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54884
The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network
Published 2025-01-01“…IntroductionMixed Lineage Kinase Domain-Like Protein (MLKL), as the executor of necroptosis and a critical factor in the inflammation, has been shown to be associated with the progression of hemorrhagic stroke. …”
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54885
Pregnancy Loss Was Associated With the Increased Risk of Cardiovascular Diseases in Middle-Aged Women: Evidence From the China Health and Retirement Longitudinal Study
Published 2025-01-01“…Objectives: Significant associations between pregnancy loss and risk of future maternal cardiovascular disease (CVD) have been found in Western countries, but the association in China is still unclear. …”
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54886
Dietary protein requirement of Chinese hook snout carp (Opsariichthys bidens) and transcriptomic analysis of the liver in response to different protein diets
Published 2025-03-01“…The Chinese hook snout carp (Opsariichthys bidens) is a newly developed economic fish species for its good taste, high nutritional content, and suitability for aquaculture in southeastern China, but its dietary protein requirement has not been investigated. In this study, the fish (initial weight 12.45 ± 0.21 g) were fed five isoenergetic diets with varying protein levels (35–47 %, P35-P47) for 65 days. …”
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54887
Determining the effect of frailty on survival in advanced ovarian cancer: study protocol for a prospective multicentre national cohort study (FOLERO)
Published 2025-02-01“…Background and purpose: There is an urgent need to improve patient-selection to surgical treatment in advanced ovarian cancer as our results showed that cytoreductive surgery was without effect or even detrimental in a yet unknown subgroup of women. …”
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54888
Effects of public roads on wildlife-vehicle collisions in two protected areas, Hluhluwe-iMfolozi Park and iSimangaliso Wetland Park, in KwaZulu-Natal, South Africa
Published 2025-01-01“…As vehicle traffic density is increasing globally, particularly in Africa, where little research on the ecological impact of linear infrastructure has been done, the impact of roads on wildlife in protected areas must be determined. …”
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54889
Recent plastic technologies development of basal texture control to improve the property of wrought Mg alloys-a review
Published 2025-01-01“…Consequently, the initial dense basal texture has been decreased, the basal slip systems are significantly activated, and plasticity is greatly improved. …”
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54890
Hubungan Keteraturan Penggunaan Kortikosteroid Inhalasi dengan Tingkat Kontrol Asma Pasien Berdasarkan ACT di Poliklinik Paru RSUP Dr. M. Djamil Padang
Published 2016-01-01“…The level of asthma control can be assessed</em><em> by </em><em> using </em><em>Asthma Control Test</em><em> </em><em> (</em><em>ACT</em><em>)</em><em> questionnaire, this method is subjective but its validity has been tested. T</em><em>he objective of t</em><em>his study </em><em>was </em><em>to determine the association between regularity of inhaled corticosteroids application and patient’s level of asthma control based on ACT in the Lung Clinic of Dr. …”
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54891
Exploring the Mechanism of Skeletal Muscle in a Tacrolimus-Induced Posttransplantation Diabetes Mellitus Model on Gene Expression Profiles
Published 2020-01-01“…Tacrolimus (Tac or FK506) is a widely used immunosuppressant that has been reported to be a risk factor for PTDM and to further induce complications in heart and skeletal muscles, but the mechanism is still largely unknown. …”
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54892
Ursodeoxycholic acid relieves clinical severity of COVID-19 in patients with chronic liver diseases
Published 2025-02-01“…BackgroundThe potential effect of ursodeoxycholic acid (UDCA) on the clinical outcomes of SARS-CoV-2 in patients with chronic liver diseases has been a subject of ongoing debate since the onset of the SARS-CoV-2 pandemic in 2019. …”
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54893
Characteristics of TPT initiation and completion among people living with HIV
Published 2024-01-01“…Despite the successful scale-up of TPT in Malawi, monitoring and evaluation have been suboptimal. We utilized the Malawi Population-Based HIV Impact Assessment (MPHIA) 2020–2021 survey data to estimate TPT uptake and completion among self-reported HIV-positive persons. …”
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54894
Periodontal Indices as Predictors of Cognitive Decline: Insights from the PerioMind Colombia Cohort
Published 2025-01-01“…<b>Background</b>: Poor oral health and periodontitis have been epidemiologically linked to cognitive decline and mild cognitive impairment (MCI) in older adults. …”
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54895
Status of seawater intrusion in Mexico: A review
Published 2025-02-01“…New hydrological insights for the region: Seawater intrusion has been documented in Mexican coastal states since the 1970s. …”
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54896
Targeting sphingosine 1-phosphate receptor 3 inhibits T-cell exhaustion and regulates recruitment of proinflammatory macrophages to improve antitumor efficacy of CAR-T cells agains...
Published 2023-08-01“…However, the functional significance of S1PR3 in T-cell-based immunotherapies and the molecular mechanisms have not been fully understood.Methods Here, we studied the combination of EpCAM-specific CAR T-cell therapy with pharmacological blockade of S1PR3 against solid tumor. …”
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54897
Performance of the 2023 diagnostic criteria for MOGAD: real-world application in a Chinese multicenter cohort of pediatric and adult patients
Published 2025-01-01“…Abstract Background The clinical phenotypes of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) have been found to overlap with several other diseases. …”
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54898
Meta Analysis of Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and its association with folate and colorectal cancer
Published 2025-01-01“…MTHFR, a key enzyme in folate metabolism, has been widely studied in relation to neural tube defects and hypertension, but its role in colorectal cancer remains underexplored. …”
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54899
Little Red Dots: Rapidly Growing Black Holes Reddened by Extended Dusty Flows
Published 2025-01-01“…The James Webb Space Telescope (JWST) observations have revolutionized extragalactic research, particularly with the discovery of little red dots (LRDs), which have been discovered as a population of dust-reddened broad-line active galactic nuclei (AGNs). …”
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54900
Targeting RGMb interactions: Discovery and preclinical characterization of potent anti-RGMb antibodies blocking multiple ligand bindings
Published 2024-12-01“…Therapeutic efficacy with durable responses has been demonstrated with several antibody drugs that block key immune checkpoint receptors, including PD-1, PD-L1, and CTLA-4. …”
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