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54321
Unlocking the Potential of Receptor-Based Approaches in Diabetes Treatment
Published 2025-01-01“…Liraglutide, a GLP-1 receptor agonist, has been shown to effectively lower glucagon levels and promote weight loss. …”
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54322
The effect of rust layer damage on the corrosion resistance of Q420 bridge steels
Published 2025-01-01“…A new experimental method has been introduced in this work to achieve different levels of artificial damage on the rust layer. …”
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54323
The value of inflammation-related indicators in chemotherapy efficacy and disease-free survival of triple-negative breast cancer
Published 2025-02-01“…Inflammation-related indicators has been recognized as outcome predictors in triple-negative breast cancer (TNBC). …”
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54324
Genome-wide identification of short-chain dehydrogenases/reductases genes and functional characterization of ApSDR53C2 in melanin biosynthesis in Arthrinium phaeospermum
Published 2025-01-01“…A short-chain dehydrogenase/reductase gene has been shown to maintain the osmotic pressure of the appressorium by synthesizing fungal melanin to penetrate the plant epidermis and cause disease. …”
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54325
Evaluation of the Antimicrobial Activity of Phytochemicals from Tea and Agarwood Leaf Extracts against Isolated Bacteria from Poultry and Curd
Published 2023-01-01“…In fact, new antibiotic compounds are needed in this urgent scenario; phytoremediation is the oldest but most effective method, and research on the antibacterial properties of several types of medicinal plants has already been conducted. …”
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54326
WT1 Peptide Cancer Vaccine for Patients with Hematopoietic Malignancies and Solid Cancers
Published 2007-01-01“…The power of a tumor-associated-antigen (TAA)-derived cancer vaccine may be enhanced in combination with stronger adjuvants, helper peptide, molecular-target-based drugs, or some chemotherapy drugs, such as gemcitabine, which has been revealed to suppress regulartory T-cell function. …”
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54327
Humanities education reform exploration and practice under outcomes-based education (OBE)
Published 2020-03-01“…The concept of outcomes-based education (OBE) was first put forward in 1981 by the educator W. Spady, and has been widely valued and applied in a rapid speed. …”
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54328
Environmental Factors Affecting the Phytoplankton Composition in the Lake of Tibetan Plateau
Published 2025-01-01“…Due to the high altitude, unique geographical location, difficult accessibility and low temperature, the environmental factors influencing phytoplankton composition have rarely been investigated in the Selin Co Lake, which is the largest lake in the Tibetan Plateau. …”
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54329
Adeno-associated virus mediated artificial circular RNA for triggering cancer immunotherapy to treat prostate cancer
Published 2025-01-01“…Naturally occurring circular RNAs (circRNAs) are structurally stable and have been proved to serve as highly efficient miR-sponges and protein-sponges in cancer cells.MethodsWe chemically synthesized circRNA (ScircRNA) in vitro to achieve therapeutic dysfunction by targeting specific miRNAs. …”
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54330
The search for a blood-based biomarker for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS): from biochemistry to electrophysiology
Published 2025-02-01“…However, for clinical application, the specificity of these biomarkers to ME/CFS needs to be explored in more disease controls, and their practicality/logistics considered. …”
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54331
Enhancing Learners’ Engagement and Performance in Learning through E-Resources and Services: National Open University of Nigeria Students as Beneficiaries
Published 2024-12-01“… Enhancement of performance on learning among learners has been on the increase due to digital information and technologies provided by libraries, because of its backbone in academic pursuit. …”
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54332
Exhaustion of CD8pos central memory regulatory T cell differentiation is involved in renal allograft rejection
Published 2025-01-01“…The pathogenesis of graft deterioration in case of rejection involves the exhaustive differentiation of both CD8pos T cell subsets, but the causal mechanisms have not yet been identified.MethodsIn this study, we separately investigated the differentiation of CD8posTregs/Tresps in 134 stable KTR with no evidence of renal graft rejection, in 41 KTR diagnosed with biopsy-confirmed rejection at enrolment and in 5 patients who were unremarkable at enrolment, but developed rejection within three years of enrolment. …”
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54333
3D nanocomposites of β-TCP-H3BO3-Cu with improved mechanical and biological performances for bone regeneration applications
Published 2025-01-01“…Several characterization techniques have been used to investigate the various characteristics of fabricated porous composites. …”
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54334
Determination of Polyphenol Components of Korean Prostrate Spurge (Euphorbia supina) by Using Liquid Chromatography—Tandem Mass Spectrometry: Overall Contribution to Antioxidant Ac...
Published 2014-01-01“…The Korean prostrate spurge Euphorbia supina is a weed that has been used in folk medicine in Korea against a variety of diseases. …”
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54335
Systematic Review and Meta-Analysis of the Y-Balance Test Lower Quarter: Reliability, Discriminant Validity, and Predictive Validity
Published 2021-10-01“…# Background Deficits in dynamic neuromuscular control have been associated with post-injury sequelae and increased injury risk. …”
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54336
Preliminary study on domestication of coconut crab (Birgus latro)
Published 2007-07-01“… Preliminary study on domestication of coconut crab (Birgus latro) had been done since June - November 2004 and December - 2005 February 2006. …”
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54337
Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM
Published 2025-01-01“…For instance, inhibiting Netrin-1 has been shown to suppress tumor growth and epithelial-mesenchymal transition (EMT) characteristics in endometrial cancer. …”
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54338
Understanding stakeholder views of the use of digital therapeutic interventions within children and young people’s mental health services
Published 2025-02-01“…BackgroundProviding the growing number of children and young people seeking mental health support with timely access to care poses a significant challenge. …”
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54339
Neural Correlates of Social Perception Deficit in Schizophrenia: An Event-related Potential Study
Published 2025-01-01“…Background: Deficits in emotion recognition have been shown to be closely related to social-cognitive functioning in schizophrenic. …”
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54340
Methodological aspects in gastroenteric methane evaluation trial in water buffalo
Published 2023-11-01“… Methane (CH 4) is a potent greenhouse gas, and ruminants constitute a significant source of agricultural contributions. It has been hypothesized that the host’s genome ultimately controls rumen microbial communities, but numerous samples are needed to achieve robust results. …”
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