Total immunoglobulin E levels in induced sputum reflect asthma control status by Wenhui Chen, Xiaofang Liu, Xiujuan Yao, Yanghe Hao, Zhuo Zhou, Chengshuo Wang, Ming Wang, Luo Zhang

“…Whether local immunoglobulin E (IgE) in induced sputum reflects asthma control status has not been investigated. Methods Patients with asthma were classified as well controlled, partly controlled, and uncontrolled asthma (UCA) according to Global Initiative for Asthma 2022 guidelines. …”
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Case report: Deciphering the clinical significance of a novel partial BRCA1 exon 10 duplication in a patient with triple-negative breast cancer by Alice Faversani, Debora Manuelli, Davide Barteselli, Giulia Melloni, Carlo Santaniello, Luigi Corsaro, Luigi Corsaro, Davide Sacco, Davide Sacco, Davide Clerici, Laura Gargiulo, Fulvio Ferrara, Lucy Costantino

“…Although new ClinGen ENIGMA guidelines have been produced to provide tools for the accurate interpretation of variants in the BRCA1 and BRCA2 genes, defining the clinical significance of copy number variants, particularly duplications, remains a challenging goal that requires complex approaches to accurately determine the role of such variants. …”
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Evaluation of mechanical and thermal performance of jute and coconut fiber-reinforced epoxy composites with rice husk ash for wall insulation applications by Md. Ahtesham Akhter, Dipayan Mondal, Arup Kumar Debnath, Md. Ashraful Islam, Md. Sanaul Rabbi

“…Furthermore, the heat transfer analysis has been studied analytically by considering two types of wall insulation configurations (type 1 and type 2). …”
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Kaempferol protects against high-salt-induced hypertension and vascular endothelial injury by inhibiting ferroptosis through the ATF4/ACSL4 pathway by Qiuer Liang, Minghao Chen, Guangtian Chen, Pengli Xu, Lai Kwan Lam, Pengcheng Xie, Ting Xie, Wanqing Tu, Tianhao Liu, Xiaopeng Peng, Haoyao Yuan, Liguo Chen, Ya Xiao

“…To date, no specific treatments have been developed for high-salt-induced hypertensive vascular damage, emphasizing the need to elucidate its underlying molecular mechanisms for therapeutic innovation. …”
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Wild pink bayberry free phenolic extract induces mitochondria-dependent apoptosis and G0/G1 cell cycle arrest through p38/MAPK and PI3K/Akt pathway in MDA-MB-231 cancer cells by Wen Xia, Er-sheng Gong, Yanyun Lin, Bisheng Zheng, Wenhan Yang, Tong Li, Sheng Zhang, Peng Li, Rui-hai Liu

“…Polyphenol-rich foods have been shown to be good for cancer prevention as powerful antioxidants. …”
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The Pro12Ala Polymorphism of PPAR-γ Gene Is Associated with Sepsis Disease Severity and Outcome in Chinese Han Population by Guoda Ma, Haiyang Wang, Guixi Mo, Lili Cui, You Li, Yiming Shao, Xin Liu, Yuliu Xie, Jia Li, Jiawu Fu, Hua Tao, Bin Zhao, Liangqing Zhang, Keshen Li

“…Therefore, PPAR-γ has been suggested as a candidate gene for sepsis. In the present study, we investigated the association between the Pro12Ala polymorphism of PPAR-γ and sepsis in a Han Chinese population. …”
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Globular-shaped Aβ oligomers have diverse mechanisms for promoting Aβ aggregations with the facilitation of fibril elongation by Hiroto Nakano, Sadao Hikishima, Makoto Mori, Jota Minamikawa, Daiki Muramatsu, Yasuhiro Sakashita, Tokuhei Ikeda, Moeko Noguchi-Shinohara, David B. Teplow, Kenjiro Ono

“…We also showed that the molecular interaction of gAβO was altered by the presence and amount of MF seeds in the reaction buffers, indicating that complex interactions would exist among different Aβ species. …”
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Yiqi Juanshen decoction alleviates renal interstitial fibrosis by targeting the LOXL2/PI3K/AKT pathway to suppress EMT and inflammation by Kaiyue Tan, Jingwei Deng, Yi Liu, Yudi Zhang, Yu Xiong, Su Yuan, Jun Liu, Zhiwei Chen, Yuanyuan Liu, Wenfu Cao

“…This study evaluates YQJSD’s effectiveness in ameliorating RIF and explores the underlying molecular mechanisms using the unilateral ureteral obstruction (UUO) model. YQJSD has been shown to effectively reduce serum creatinine and blood urea nitrogen levels, decrease extracellular matrix deposition, and down-regulate the expression of α-SMA, COL4α1, Fibronectin (FN). …”
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Sport innovation structure landscape in Switzerland and abroad by Christelle Ganné-Chedeville, Solange Emmenegger, Hippolyt Kempf, Cornel Gübeli

“…In order to reinforce sport actors, push innovation and better transfer knowledge into practice, an analysis has been conducted to understand the structures and models existing which support sport in research and innovation. …”
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Metabolic dysfunction-associated fatty liver disease and risk of nephrolithiasis: a sizeable cross-sectional study by Shengqi Zheng, Tianchi Hua, Guicao Yin, Wei Zhang, Xiaoxiang Wang, Lezhong Qi, Xiayong Jing, Qibing Fan, Xiaoping Yu, Yifan Li

“…ObjectiveMetabolic dysfunction-associated fatty liver disease (MAFLD) and nephrolithiasis are two common metabolic diseases, but their relationship has not yet been thoroughly studied. Therefore, this study aimed to explore the association between MAFLD and nephrolithiasis and to assess the effect of MAFLD on the risk of nephrolithiasis.Materials and methodsThis cross-sectional study included 96,767 adults from China. …”
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Evaluation of low cryptococcal antigen titer as determined by the lateral flow assay in serum and cerebrospinal fluid among HIV-negative patients: a retrospective diagnostic accura... by Xuan Wang, Jia-Hui Cheng, Ling-Hong Zhou, Jun-Hao Zhu, Rui-Ying Wang, Hua-Zhen Zhao, Ying-Kui Jiang, Li-Ping Huang, Ching-Wan Yip, Chun-Xing Que, Min Zhu, Li-Ping Zhu

“…Although the cryptococcal antigen (CrAg) lateral flow assay (LFA) has been widely used in clinical settings due to its high sensitivity and specificity, the diagnostic value of a low CrAg LFA titers remains unclear. …”
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Taxifolin increased semen quality of Duroc boars by improving gut microbes and blood metabolites by Yexun Zhou, Yexun Zhou, Liang Chen, Hui Han, Hui Han, Bohui Xiong, Ruqing Zhong, Yue Jiang, Lei Liu, Haiqing Sun, Jiajian Tan, Xiaowei Cheng, Martine Schroyen, Yang Gao, Yong Zhao, Hongfu Zhang

“…Taxifolin (TAX), as a natural flavonoid, has been widely focused on due to its strong anti-oxidation, anti-inflammation, anti-virus, and even anti-tumor activity. …”
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Attributing heatwave-related mortality to climate change: a case study of the 2009 Victorian heatwave in Australia by Sarah E Perkins-Kirkpatrick, Linda Selvey, Philipp Aglas-Leitner, Nina Lansbury, Samuel Hundessa, Dáithí Stone, Kristie L Ebi, Nicholas John Osborne

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Simultaneous GC-FID Quantification of Main Components of Rosmarinus officinalis L. and Lavandula dentata Essential Oils in Polymeric Nanocapsules for Antioxidant Application by Perla Giovanna Silva-Flores, Luis Alejandro Pérez-López, Verónica Mayela Rivas-Galindo, David Paniagua-Vega, Sergio Arturo Galindo-Rodríguez, Rocío Álvarez-Román

“…The essential oils (EO) of R. officinalis and L. dentata have been widely used due to their antioxidant activity. …”
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Genetic Polymorphisms of Interleukin-1 Alpha and the Vitamin D Receptor in Mexican Mestizo Patients with Intervertebral Disc Degeneration by Salvador Cervin Serrano, Dalia González Villareal, Maribel Aguilar-Medina, Jose Guillermo Romero-Navarro, Jose Geovanni Romero Quintana, Eliakym Arámbula Meraz, Ignacio Osuna Ramírez, Veronica Picos-Cárdenas, Julio Granados, Iris Estrada-García, Guzman Sánchez-Schmitz, Rosalío Ramos-Payán

“…Several conditions, such as occupational activities, gender, age, and obesity, have been associated with IDD. However, the development of this disease has strong genetic determinants. …”
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Denervation as a Common Mechanism Underlying Different Pulmonary Vein Isolation Strategies for Paroxysmal Atrial Fibrillation: Evidenced by Heart Rate Variability after Ablation by Kejing Wang, Dong Chang, Zhenliang Chu, Yanzong Yang, Lianjun Gao, Shulong Zhang, Yunlong Xia, Yingxue Dong, Xiaomeng Yin, Peixin Cong, Jingjing Jia

“…Segmental and circumferential pulmonary vein isolations (SPVI and CPVI) have been demonstrated to be effective therapies for paroxysmal atrial fibrillation (PAF). …”
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Increase in disturbance-induced canopy gaps leads to reorganization of Central European bird communities by Anne Graser, Claudia Frank, Friederike Kunz, Andreas Schuldt, Cornelius Senf, Christoph Sudfeldt, Sven Trautmann, Johannes Kamp

“…How those changes affect biodiversity has, however, rarely been quantified over larger spatial and longer temporal scales, mostly because concurrent datasets on biodiversity trends and forest disturbances are rare. …”
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The Role of Matrix Metalloproteinases (MMP-2 and MMP-9) in Ageing and Longevity: Focus on Sicilian Long-Living Individuals (LLIs) by Patrizia Cancemi, Anna Aiello, Giulia Accardi, Rosalia Caldarella, Giuseppina Candore, Calogero Caruso, Marcello Ciaccio, Laura Cristaldi, Francesca Di Gaudio, Valentina Siino, Sonya Vasto

“…Extracellular matrix metalloproteinases (MMPs) are a group of proteins that activate substrates by enzymatic cleavage and, on the basis of their activities, have been demonstrated to play a role in ageing. Thus, in order to gain insight into the pathophysiology of ageing and to identify new markers of longevity, we analysed the activity levels of MMP-2 and MMP-9 in association with some relevant haematochemical parameters in a Sicilian population, including long-living individuals (LLIs, ≥95 years old). …”
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Intermittent auscultation fetal monitoring during labour: A systematic scoping review to identify methods, effects, and accuracy. by Ellen Blix, Robyn Maude, Elisabeth Hals, Sezer Kisa, Elisabeth Karlsen, Ellen Aagaard Nohr, Ank de Jonge, Helena Lindgren, Soo Downe, Liv Merete Reinar, Maralyn Foureur, Aase Serine Devold Pay, Anne Kaasen

“…<h4>Conclusion</h4>Although IA is the recommended method, no trials have been published that evaluate protocols on how to perform it. …”
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Migration, race, and gender: the policing of subversive solidarity actors in Morocco by Sébastien Bachelet, Maria Hagan

“…The policing of racialised migrant people in Morocco and across the Maghreb has been violent since the 1990s. The intimidation of those who support migrant people and seek to denounce human rights abuses against them has become an important dimension of border control. …”
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